Paid Clinical Trials in Kansas City, MO
As of June 2026, 489 paid clinical trials are recruiting in Kansas City, Missouri. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Kansas City offers studies at sites including University of Kansas Cancer Center - North for conditions such as Heart Failure, Breast Cancer, Malignant Solid Neoplasm, Atrial Fibrillation. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Kansas City
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Kansas City has approximately 489 recruiting research studies across a wide range of therapeutic areas. Missouri hosts Washington University School of Medicine in St. Louis and University of Kansas Medical Center's Missouri partners, known for oncology, genomics, and rare-disease research.
Top Research Study Locations in Kansas City
Researchers run research studies in Kansas City, MO at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Kansas Cancer Center - North | Stage IV Lung Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 55 |
| Children's Mercy Hospital | Bronchopulmonary Dysplasia, Congenital Heart Disease (CHD), Hypertension | 52 |
| Children's Mercy Hospitals and Clinics | Neuroblastoma, Amblyopia, B Acute Lymphoblastic Leukemia | 44 |
| University Health Truman Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 | 37 |
| University of Kansas Cancer Center - Briarcliff | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Recurrent Lung Non-Small Cell Carcinoma | 35 |
| Saint Luke's Hospital of Kansas City | Heart Failure, Aortic Valve Disease, Breast Cancer | 35 |
| Research Medical Center | Atrial Fibrillation, Stroke, Anatomic Stage I Breast Cancer AJCC v8 | 16 |
| Saint Luke's Cancer Institute | Breast Cancer, Breast Neoplasms, Metastatic Breast Cancer | 15 |
| Kansas City Veterans Affairs Medical Center | Chronic Lymphocytic Leukemia, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma | 13 |
| Children's Mercy Kansas City | ALL, Childhood, Behavior, Health, Bronchiolitis Acute | 12 |
| Children's Mercy | Acute Brain Injury, Acute Respiratory Distress Syndrome, Angelman Syndrome | 10 |
| Kansas City VA Medical Center, Kansas City, MO | Metastatic Prostate Cancer, Adult Growth Hormone Deficiency, Atherosclerosis | 7 |
| Kansas City VA Medical Center | Heart Failure, Atherosclerotic Cardiovascular Disease in Patients With ESKD, Eosinophilic Esophagitis (EoE) | 7 |
| Research Medical Center Clinic | Atrial Fibrillation, Stroke, Aortic Stenosis | 7 |
| St. Luke's Hospital of Kansas City | Amyloid Cardiomyopathy, Amyloidosis, Aortic Stenosis | 7 |
| The Children's Mercy Hospital | Acute Liver Failure, Acute Liver Injury, Alagille Syndrome | 7 |
| Kansas City Research Institute | Chronic Idiopathic Constipation (CIC), EPP, Liver Fibrosis | 6 |
| Saint Luke's Hospital | HPV-unrelated Head and Neck Squamous Cell Carcinoma, Intra-uterine Device Placement, Mitral Valve Prolapse | 5 |
| University of Kansas Medical Center | Smoking Reduction, Idiopathic Pulmonary Fibrosis (IPF), Severe Sepsis | 5 |
| Clinical Trial Site | Angelman Syndrome, Breast Cancer, ER Positive Breast Cancer | 4 |
| Children's Mercy Research Institute | Anorexia Nervosa, Atypical, Binge Eating, Bulimia Nervosa | 4 |
| Children's Mercy Adelle Hall Campus | Cerebroside Lipidosis Syndrome, Gaucher Disease, Glucocerebrosidase Deficiency Disease | 4 |
| AMR Clinical | Healthy Adults, Metabolic Dysfunction-Associated Steatotic Liver Disease, Osteoarthritis | 3 |
| AMR Kansas City | Diabetic Peripheral Neuropathic Pain, RSV Infection | 3 |
| Children's Mercy Hospital and Clinics | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Alagille Syndrome | 3 |
| MidAmerica Cancer Care | Advanced Melanoma, Large B-cell Lymphoma, Myelodysplastic Syndromes | 3 |
| North Kansas City Hospital | Heart Failure, Lumbar Spinal Stenosis, Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma | 3 |
| Saint Luke's Mid America Heart Institute | Cardiovascular Diseases, Tricuspid Valve Disease, Heart Failure | 3 |
| St. Luke's Hospital | Cardiovascular Diseases, Heart Diseases, Heart Failure | 3 |
| University Health | Hypovolemia, Overweight and Obesity, PreDiabetes | 3 |
| KC Care Health Center | HIV Infections, ART, Noncompliance, Patient | 3 |
| Kansas City Physician Partners | Radiographic Axial Spondyloarthritis, Arthritis, Rheumatoid, Psoriatic Arthritis | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Alliance for Multispecialty Research - Kansas City | Atherosclerotic Cardiovascular Disease, Obesity, Overweight | 2 |
| Children's Mercy Hospital Kansas City | Cerebral Palsy, Dyskinetic, Cerebral Palsy, Dystonic-Rigid, Dystonia | 2 |
| Children's Mercy Hospital Kansas City - Cardiology | Heart Failure (Pediatric), Left Ventricular Systolic Dysfunction | 2 |
| Children's Mercy Hospital Kansas City - Nephrology | Chronic Kidney Disease, Proteinuria, Children | 2 |
| Clinical Research Consultants | Atherosclerotic Cardiovascular Disease in Patients With ESKD, Chronic Kidney Disease | 2 |
| Clinical Research Consultants, LLC | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Diabetic Kidney Disease (DKD) | 2 |
| GSK Investigational Site | HIV Infections | 2 |
| HCA Midwest Division | Early Breast Cancer, Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer | 2 |
| Mid-America Gastro-Intestinal Consultants | Crohn's Disease, Ulcerative Colitis | 2 |
| Moyes Eye Center | Corneal Endothelial Decompensation, Fuchs Endothelial Corneal Dystrophy, Primary Open Angle Glaucoma | 2 |
| Saint Luke's Hospital of Kansas City Mid America | Aortic Stenosis, Aortic Stenosis, Calcific, Aortic Stenosis, Severe | 2 |
| Saint Luke's Hospital of Kansas City/MidAmerica Heart and Lung Surgeons | Left Ventricular Fibrosis, Mitral Valve Prolapse, Mitral Valve Regurgitation | 2 |
| Saint Lukes Mid America Heart Institute | Coronary Artery Disease, Heart Failure With Preserved Ejection Fraction (HFpEF) | 2 |
| The University of Kansas Cancer Center - North | Advanced NSCLC, Breast Cancer, Lung Cancer | 2 |
| Truman Medical Centers | Anatomic Stage IV Breast Cancer AJCC v8, Cardiotoxicity, Elevated CA15-3 or CEA or CA27-29 | 2 |
| University of Kansas Cancer Center | Cutaneous Melanoma, Stage II, Stage III Fallopian Tube Cancer, Stage III Ovarian Cancer | 2 |
| University of Missouri-Kansas City | Diabetes, Food Security, Nutrition Security | 2 |
Active & Upcoming Studies in Kansas City (2026)
Recruiting trials in Kansas City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (157 active studies)
- Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer · Phase 2 · National Cancer Institute (NCI)
- DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy · Phase 3 · Boehringer Ingelheim
Cardiovascular (60 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Diabetes & metabolic (23 active studies)
- Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans · University of Missouri, Kansas City
- Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus · Phase 2 · Hanmi Pharmaceutical Company Limited
Pediatric (21 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Neurology & pain (12 active studies)
- A Feasibility Trial of Virtual Reality Neurofeedback for Adolescents With Migraine · Children's Mercy Hospital Kansas City
- Impact of Steerable Delivery Sheaths on Successful Closure of LA A With AMULET · Kansas City Heart Rhythm Research Foundation
HIV / STI (7 active studies)
Vaccines (6 active studies)
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Mental health & behavior (6 active studies)
- PTSD Screening in Pregnant Black Women · Emory University
- Clinic-level Implementation of mHealth to Improve HIV Viral Suppression for Patients With Substance Use Disorders · University of Wisconsin, Madison
Eye & vision (6 active studies)
- A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease · Phase 3 · AbbVie
- Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma · Phase 4 · Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,
Common conditions studied in Kansas City
- Heart Failure (18 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Breast Cancer (13 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Malignant Solid Neoplasm (8 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Atrial Fibrillation (7 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
- Neuroblastoma (7 active studies). Recruiting Neuroblastoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Myeloid Leukemia (6 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
Leading research sponsors in Kansas City
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Mercy Hospital Kansas City
- Children's Oncology Group
- SWOG Cancer Research Network
Local regulations and guidelines
Clinical trials in Missouri are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Missouri research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Kansas City. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Kansas City
Hipa.ai aggregates every recruiting study in Kansas City from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Kansas City?
There are approximately 489 recruiting clinical trials in Kansas City, Missouri listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Kansas City pay participants?
Most recruiting trials in Kansas City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Kansas City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Kansas City?
The most common conditions under active study in Kansas City include Heart Failure (18), Breast Cancer (13), Malignant Solid Neoplasm (8), Atrial Fibrillation (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Kansas City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Kansas City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Kansas City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Kansas City?
Recruiting research sites in Kansas City include University of Kansas Cancer Center - North, Children's Mercy Hospital, Children's Mercy Hospitals and Clinics, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Kansas City right now?
The largest active categories in Kansas City are Cancer & tumors (157), Cardiovascular (60), Diabetes & metabolic (23). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.