Depression Clinical Trials in North Charleston, SC
As of June 2026, 3 paid clinical trials are recruiting for Depression in North Charleston, South Carolina. Depression studies test rapid-acting antidepressants including ketamine derivatives, psilocybin-assisted therapy, and neuromodulation approaches. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in North Charleston
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3 clinical trials for Depression
·Clear filters·↓ Download CSVA Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
About research studies in North Charleston
North Charleston has approximately 55 recruiting research studies across a wide range of therapeutic areas. South Carolina hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in North Charleston
Researchers run research studies in North Charleston, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Coastal Carolina Research Center | Attention-Deficit/Hyperactivity Disorder, Chronic Idiopathic Constipation (CIC), Chronic Low-back Pain | 9 |
| Coastal Carolina Research Ctr | Obesity, Overweight | 3 |
| Coastal Carolina Research Center - Main | Gout, Tophaceous Gout | 2 |
| MUSC Shawn Jenkins Children's Hospital - Cardiology | Heart Failure (Pediatric), Left Ventricular Systolic Dysfunction | 2 |
| Monroe Biomedical Research | Asthma, Urinary Incontinence | 2 |
| Monroe Biomedical Research Charleston | Chronic Obstructive Pulmonary Disease, Type II Diabetes Mellitus | 2 |
| North Charleston, South Carolina | Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2 | 2 |
| Autobahn Site #128 | Major Depressive Disorder | 1 |
| Carolina Endocrine Associates Llc /ID# 259640 | Hypothyroidism | 1 |
| Charleston ENT & Allergy | Chronic Rhinosinusitis Without Nasal Polyps | 1 |
| Charleston ENT and Allergy | Chronic Spontaneous Urticaria (CSU) | 1 |
| Coastal Carolina Res Ctr | Knee Osteoarthritis (OA), Obesity | 1 |
| Coastal Carolina Research | Major Depressive Disorder | 1 |
| Coastal Carolina Research Center - North Charleston /ID# 257227 | Migraine | 1 |
| Coastal Carolina Research Center, LLD | Knee Osteoarthritis | 1 |
| Enveda Investigative Site | Asthma | 1 |
| HCA - Trident Medical Center | Atrial Fibrillation | 1 |
| Kailera Clinical Site | Obesity | 1 |
| Kymera Investigative Site | Eosinophilic Asthma | 1 |
| Local Institution - 0418 | Plaque Psoriasis | 1 |
| Low Country Urology Clinics | Non-Muscle Invasive Bladder Neoplasms | 1 |
| Low county Urology Clinics | Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma | 1 |
| Lowcountry Lung and Critical Care | Chronic Obstructive Pulmonary Disease | 1 |
| Lowcountry Lung and Critical Care PA | Chronic Obstructive Pulmonary Disease | 1 |
| Lowcountry Orthopaedics and Sports Medicine | Degenerative Disc Disease | 1 |
Active & Upcoming Studies in North Charleston (2026)
Recruiting trials in North Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Diabetes & metabolic (7 active studies)
- Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events · Phase 1 · Novo Nordisk A/S
- A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain · Phase 3 · Novo Nordisk A/S
Cancer & tumors (5 active studies)
- A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer · Phase 3 · UroGen Pharma Ltd.
- Sacral Neuromodulation for Male Overactive Bladder (MOAB) · Axonics, Inc.
Cardiovascular (5 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Neurology & pain (4 active studies)
- Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy · Phase 3 · Vertex Pharmaceuticals Incorporated
- Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine · Phase 3 · AbbVie
Mental health & behavior (2 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse · Phase 2 · Eli Lilly and Company
Pediatric (2 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Common conditions studied in North Charleston
- Obesity (5 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Asthma (3 active studies). Asthma research tests biologic therapies targeting IL-4, IL-5, and TSLP pathways for moderate-to-severe and eosinophilic disease.
- Atopic Dermatitis (2 active studies). Atopic dermatitis studies test IL-13 inhibitors, JAK inhibitors, and next-generation topical therapies for moderate-to-severe eczema.
- Atrial Fibrillation (2 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
- Binge-Eating Disorder (2 active studies). Recruiting Binge-Eating Disorder studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Chronic Obstructive Pulmonary Disease (2 active studies). COPD research evaluates biologic therapies, triple-inhaler combinations, and new anti-inflammatory agents to reduce exacerbations.
Leading research sponsors in North Charleston
- Novo Nordisk A/S
- AbbVie
- AstraZeneca
- Axsome Therapeutics, Inc.
- Bayer
Local regulations and guidelines
Clinical trials in South Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. South Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in North Charleston. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in North Charleston
Hipa.ai aggregates every recruiting study in North Charleston from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in North Charleston?
There are approximately 55 recruiting clinical trials in North Charleston, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in North Charleston pay participants?
Most recruiting trials in North Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in North Charleston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in North Charleston?
The most common conditions under active study in North Charleston include Obesity (5), Asthma (3), Atopic Dermatitis (2), Atrial Fibrillation (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in North Charleston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in North Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in North Charleston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in North Charleston?
Recruiting research sites in North Charleston include Coastal Carolina Research Center, Coastal Carolina Research Ctr, Coastal Carolina Research Center - Main, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in North Charleston right now?
The largest active categories in North Charleston are Diabetes & metabolic (7), Cancer & tumors (5), Cardiovascular (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.