Mental health Clinical Trials in North Charleston, SC

As of June 2026, 3 paid clinical trials are recruiting for Mental health in North Charleston, South Carolina. Mental health research covers new pharmacotherapies, psychotherapies, and digital interventions for depression, anxiety, PTSD, bipolar disorder, and sleep — including treatments for treatment-resistant cases. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

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3 clinical trials for Mental health

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About research studies in North Charleston

North Charleston has approximately 55 recruiting research studies across a wide range of therapeutic areas. South Carolina hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.

Top Research Study Locations in North Charleston

Researchers run research studies in North Charleston, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
Coastal Carolina Research CenterAttention-Deficit/Hyperactivity Disorder, Chronic Idiopathic Constipation (CIC), Chronic Low-back Pain9
Coastal Carolina Research CtrObesity, Overweight3
Coastal Carolina Research Center - MainGout, Tophaceous Gout2
MUSC Shawn Jenkins Children's Hospital - CardiologyHeart Failure (Pediatric), Left Ventricular Systolic Dysfunction2
Monroe Biomedical ResearchAsthma, Urinary Incontinence2
Monroe Biomedical Research CharlestonChronic Obstructive Pulmonary Disease, Type II Diabetes Mellitus2
North Charleston, South CarolinaIdiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 22
Autobahn Site #128Major Depressive Disorder1
Carolina Endocrine Associates Llc /ID# 259640Hypothyroidism1
Charleston ENT & AllergyChronic Rhinosinusitis Without Nasal Polyps1
Charleston ENT and AllergyChronic Spontaneous Urticaria (CSU)1
Coastal Carolina Res CtrKnee Osteoarthritis (OA), Obesity1
Coastal Carolina ResearchMajor Depressive Disorder1
Coastal Carolina Research Center - North Charleston /ID# 257227Migraine1
Coastal Carolina Research Center, LLDKnee Osteoarthritis1
Enveda Investigative SiteAsthma1
HCA - Trident Medical CenterAtrial Fibrillation1
Kailera Clinical SiteObesity1
Kymera Investigative SiteEosinophilic Asthma1
Local Institution - 0418Plaque Psoriasis1
Low Country Urology ClinicsNon-Muscle Invasive Bladder Neoplasms1
Low county Urology ClinicsUpper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma1
Lowcountry Lung and Critical CareChronic Obstructive Pulmonary Disease1
Lowcountry Lung and Critical Care PAChronic Obstructive Pulmonary Disease1
Lowcountry Orthopaedics and Sports MedicineDegenerative Disc Disease1

Active & Upcoming Studies in North Charleston (2026)

Recruiting trials in North Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Common conditions studied in North Charleston

  • Obesity (5 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
  • Asthma (3 active studies). Asthma research tests biologic therapies targeting IL-4, IL-5, and TSLP pathways for moderate-to-severe and eosinophilic disease.
  • Atopic Dermatitis (2 active studies). Atopic dermatitis studies test IL-13 inhibitors, JAK inhibitors, and next-generation topical therapies for moderate-to-severe eczema.
  • Atrial Fibrillation (2 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
  • Binge-Eating Disorder (2 active studies). Recruiting Binge-Eating Disorder studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Chronic Obstructive Pulmonary Disease (2 active studies). COPD research evaluates biologic therapies, triple-inhaler combinations, and new anti-inflammatory agents to reduce exacerbations.

Leading research sponsors in North Charleston

  • Novo Nordisk A/S
  • AbbVie
  • AstraZeneca
  • Axsome Therapeutics, Inc.
  • Bayer

Local regulations and guidelines

Clinical trials in South Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. South Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in North Charleston. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in North Charleston

Hipa.ai aggregates every recruiting study in North Charleston from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in North Charleston?

There are approximately 55 recruiting clinical trials in North Charleston, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in North Charleston pay participants?

Most recruiting trials in North Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in North Charleston?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in North Charleston?

The most common conditions under active study in North Charleston include Obesity (5), Asthma (3), Atopic Dermatitis (2), Atrial Fibrillation (2), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in North Charleston?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in North Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in North Charleston?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in North Charleston?

Recruiting research sites in North Charleston include Coastal Carolina Research Center, Coastal Carolina Research Ctr, Coastal Carolina Research Center - Main, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in North Charleston right now?

The largest active categories in North Charleston are Diabetes & metabolic (7), Cancer & tumors (5), Cardiovascular (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

Browse more clinical trials

Related healthcare resources in South Carolina

Trials by condition in North Charleston

Conditions in Mental health (North Charleston, SC)