Study of DONQ52 in Active Celiac Disease
for Celiac Disease
Drug: DONQ52
Sites in Rochester +56 more locations
Sponsor: Chugai Pharmaceutical
Sex: All·Age: 18 - 75
Code: NCT07239336·Phase 2·Recruiting·Listed Nov 2025
Clinical Trials at Mayo Clinic - Rochester
As of August 2026, 29 paid clinical trials are recruiting at Mayo Clinic - Rochester, located at 5360 KINGSBURY PL NW, ROCHESTER, MN 55901-2192, phone (507) 284-2511 in Rochester, Minnesota. Active studies at this site cover conditions such as Malignant Solid Neoplasm, Heart Failure and Multiple Myeloma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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29 clinical trials at Mayo Clinic - Rochester
·Clear filters·A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
for Chronic Spontaneous Urticaria (CSU)
Drug: Remibrutinib
Sites in Rochester, Minneapolis +126 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18+
Code: NCT06868212·Phase 3·Recruiting·Listed Mar 2025
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
for Moderate Aortic Valve Stenosis
Drug: Ataciguat
Sites in Rochester, Maplewood +67 more locations
Sponsor: Kardigan, Inc.
Sex: All·Age: 50+
Code: NCT07001800·Phase 2, Phase 3·Recruiting·Listed Jun 2025
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
for Non Small Cell Lung Cancer
Sites in Rochester, Minneapolis +42 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06312137·Phase 3·Recruiting·Listed Mar 2024
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
for Amyloidosis
Drug: Acoramidis
Sites in Rochester +39 more locations
Sponsor: Eidos Therapeutics, a BridgeBio company
Sex: All·Age: 18 - 75
Code: NCT06563895·Phase 3·Recruiting·Listed Aug 2024
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
for Glioma
Sites in Rochester +41 more locations
Sponsor: Nuvation Bio Inc.
Sex: All·Age: 18+
Code: NCT05303519·Phase 3·Recruiting·Listed Mar 2022
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
for Triple Negative Breast Cancer
Sites in Rochester +25 more locations
Sponsor: Day One Biopharmaceuticals, Inc.
Sex: All·Age: 18+
Code: NCT05377996·Phase 1, Phase 2·Recruiting·Listed May 2022
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
for Metastatic Breast Cancer
Sites in Rochester, Minneapolis +29 more locations
Sponsor: LeonaBio
Sex: All·Age: 18+
Code: NCT05696626·Phase 3·Recruiting·Listed Jan 2023
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Rochester, Minneapolis +42 more locations
Sponsor: Kura Oncology, Inc.
Sex: All·Age: 18+
Code: NCT05735184·Phase 1·Recruiting·Listed Feb 2023
KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)
for GIST - Gastrointestinal Stromal Tumor
Sites in Rochester +16 more locations
Sponsor: Kumquat Biosciences Inc.
Sex: All·Age: 18+
Code: NCT07406633·Phase 2·Recruiting·Listed Feb 2026
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
for Lymphoma, Non-Hodgkin's
Drug: LY4584180
Sites in Rochester +20 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07226843·Phase 1·Recruiting·Listed Nov 2025
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
for Ovarian Neoplasms
Sites in Rochester +18 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07213791·Phase 1·Recruiting·Listed Oct 2025
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
for Cytomegalovirus Prophylaxis
Sites in Rochester, Minneapolis +16 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: Up to 17
Code: NCT07199465·Phase 1·Recruiting·Listed Sep 2025
Diagnosing Epilepsy To EffeCT Change
for Epilepsy
Sites in Rochester, Minneapolis +17 more locations
Sponsor: Epiminder America, Inc.
Sex: All·Age: 18 - 75
Code: NCT07110337·Recruiting·Listed Aug 2025
A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )
for Lymphoma, Non-Hodgkin
Sites in Rochester +22 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07101328·Phase 1·Recruiting·Listed Aug 2025
Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up
for Epilepsy
Sites in Rochester +15 more locations
Sponsor: Epiminder America, Inc.
Sex: All·Age: 18 - 75
Code: NCT07110454·Recruiting·Listed Aug 2025
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)
for Non-small Cell Lung Cancer (NSCLC)
Sites in Rochester, Minneapolis +8 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06170788·Phase 3·Recruiting·Listed Dec 2023
A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma
for Diffuse Large B-cell Lymphoma (DLBCL)
Drug: Odronextamab
Sites in Rochester +19 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT06091865·Phase 3·Recruiting·Listed Oct 2023
Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
for Recurrent Ovarian Cancer
Drug: Cemiplimab
Sites in Rochester +8 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: Female·Age: 18+
Code: NCT03564340·Phase 1, Phase 2·Recruiting·Listed Jun 2018
A Study Assessing HMB-002 in Participants With Von Willebrand Disease
for Von Willebrand Disease (VWD)
Sites in Rochester +12 more locations
Sponsor: Hemab ApS
Sex: All·Age: 16 - 69
Code: NCT06754852·Phase 1, Phase 2·Recruiting·Listed Jan 2025
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
for Autosomal Recessive Polycystic Kidney (ARPKD)
Sites in Rochester +5 more locations
Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Sex: All·Age: 28 Days - 18
Code: NCT04782258·Phase 3·Recruiting·Listed Mar 2021
A Study of Bleeding and Treatment in Participants With Von Willebrand Disease
for Von Willebrand Disease (VWD)
Sites in Rochester +12 more locations
Sponsor: Hemab ApS
Sex: All·Age: 16+
Code: NCT06610201·Recruiting·Listed Sep 2024
A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
for Solid Tumor Malignancies
Sites in Rochester +14 more locations
Sponsor: Kumquat Biosciences Inc.
Sex: All·Age: 18+
Code: NCT06994806·Phase 1·Recruiting·Listed May 2025
Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)
for Tricuspid Regurgitation
Sites in Rochester, Minneapolis +8 more locations
Sponsor: VDyne, Inc.
Sex: All·Age: 18+
Code: NCT05848284·Recruiting·Listed May 2023
Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection
for Viral Pneumonia
Sites in Rochester +21 more locations
Sponsor: Synairgen Research Ltd.
Sex: All·Age: 18+
Code: NCT06999603·Phase 2·Recruiting·Listed May 2025
A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)
for VEXAS
Drug: Pacritinib
Sites in Rochester +8 more locations
Sponsor: Swedish Orphan Biovitrum
Sex: All·Age: 18+
Code: NCT06782373·Phase 2·Recruiting·Listed Jan 2025
A Study of CTD402 in T-ALL/LBL Patients
for Acute Lymphocytic Leukemia Refractory
Sites in Rochester +7 more locations
Sponsor: Imviva Bio
Sex: All·Age: 12+
Code: NCT07070219·Phase 1, Phase 2·Recruiting·Listed Jul 2025
Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors
for Solid Tumors
Sites in Rochester +5 more locations
Sponsor: Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.
Sex: All·Age: 18 - 75
Code: NCT06963281·Phase 1·Recruiting·Listed May 2025
Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)
for High Grade Neuroendocrine Neoplasms
Sites in Rochester +1 more location
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+
Code: NCT06926634·Phase 2·Recruiting·Listed Apr 2025
Common conditions studied in Rochester
- Malignant Solid Neoplasm (19 active studies)
- Heart Failure (16 active studies)
- Multiple Myeloma (16 active studies)
- Ovarian Cancer (15 active studies)
- Breast Cancer (14 active studies)
- Healthy (14 active studies)
Leading research sponsors in Rochester
- Mayo Clinic
- National Cancer Institute (NCI)
- AstraZeneca
- Eli Lilly and Company
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Rochester?
There are approximately 1,200 recruiting clinical trials in Rochester, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Rochester pay participants?
Most recruiting trials in Rochester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Rochester?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Rochester?
The most common conditions under active study in Rochester include Malignant Solid Neoplasm (19), Heart Failure (16), Multiple Myeloma (16), Ovarian Cancer (15), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Rochester?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Rochester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Rochester?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Rochester?
Recruiting research sites in Rochester include Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic Rochester, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Rochester right now?
The largest active categories in Rochester are Cancer & tumors (371), Cardiovascular (93), Neurology & pain (69). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Mayo Clinic - Rochester?
Mayo Clinic - Rochester is located at 5360 KINGSBURY PL NW, ROCHESTER, MN 55901-2192. Use the Google Maps link in the intro above to get directions.
How do I contact Mayo Clinic - Rochester?
You can reach Mayo Clinic - Rochester by phone at (507) 284-2511. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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