Paid Clinical Trials in Santa Ana, CA

As of June 2026, 64 paid clinical trials are recruiting in Santa Ana, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Santa Ana offers studies at sites including Syrentis Clinical Research for conditions such as Obesity, Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Trials by specialty in Santa Ana

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About research studies in Santa Ana

Santa Ana has approximately 64 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.

Top Research Study Locations in Santa Ana

Researchers run research studies in Santa Ana, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
Syrentis Clinical ResearchAlzheimer Disease, Alzheimers Disease, AD9
Southern California Clinical ResearchObesity, Overweight, Alopecia Areata4
Orange County Retina Medical GroupAge-related Macular Degeneration (AMD), Geographic Atrophy (GA), Geographic Atrophy Secondary to Age-related Macular Degeneration4
Santa Ana, CaliforniaIdiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 23
Wolverine Clinical TrialsHidradenitis Suppurativa, Osteoarthritis, Overweight or Obesity3
89bio Clinical Study SiteMetabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis2
Orange County Retina Med GroupNeovascular Age-Related Macular Degeneration, Neovascular Age-related Macular Degeneration2
Oruka Therapeutics Investigative SitePlaque Psoriasis2
Paje OptometricMyopia, Juvenile Myopia, Myopia Progression2
SDS Clinical Trials, Inc.Narcolepsy Type 1, OSA2
Southern California Dermatology, Inc.Alopecia, Areata Alopecia, Hair Diseases2
TakedaIdiopathic Hypersomnia, Narcolepsy Type 22
Southern California DermatologyDermatitis, Atopic, Dermatitis Atopic2
Akerman MedBacterial Vaginosis, Fungal Vaginal Infections1
Anthos InvestigativeAtrial Fibrillation (AF)1
Artiva Investigational Site Santa AnaIIM, Idiopathic Inflammatory Myopathies (IIMs), Myositis1
Clemente Clinical ResearchDiabetic Foot Ulcer, Wound Heal1
Clinical Study SiteNon-Small Cell Lung Cancer1
Helping Hands Medical Associates INCCardiovascular Disease and Lipoprotein(a)1
InvestigativeHidradenitis Suppurativa1
Kailera Clinical SiteObesity1
Local Institution - 007-898-CAdvanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer1
Local Institution - 0136Bipolar Disorder Type I With Mania1
Novartis Investigative SiteAtopic Dermatitis1
Paragon RX ClinicalOsteoarthritis, Knee1

Active & Upcoming Studies in Santa Ana (2026)

Recruiting trials in Santa Ana grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Common conditions studied in Santa Ana

  • Obesity (4 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
  • Idiopathic Hypersomnia (3 active studies). Recruiting Idiopathic Hypersomnia studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Narcolepsy Type 1 (3 active studies). Recruiting Narcolepsy Type 1 studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Narcolepsy Type 2 (3 active studies). Recruiting Narcolepsy Type 2 studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Overweight (3 active studies). Recruiting Overweight studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Alzheimer Disease (2 active studies). Alzheimer's research investigates anti-amyloid antibodies, tau-targeted therapies, and lifestyle interventions aimed at slowing cognitive decline.

Leading research sponsors in Santa Ana

  • Eli Lilly and Company
  • Axsome Therapeutics, Inc.
  • AstraZeneca
  • Hoffmann-La Roche
  • Pfizer

Local regulations and guidelines

Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Santa Ana. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Santa Ana

Hipa.ai aggregates every recruiting study in Santa Ana from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Santa Ana?

There are approximately 64 recruiting clinical trials in Santa Ana, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Santa Ana pay participants?

Most recruiting trials in Santa Ana compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Santa Ana?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Santa Ana?

The most common conditions under active study in Santa Ana include Obesity (4), Idiopathic Hypersomnia (3), Narcolepsy Type 1 (3), Narcolepsy Type 2 (3), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Santa Ana?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Santa Ana on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Santa Ana?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Santa Ana?

Recruiting research sites in Santa Ana include Syrentis Clinical Research, Southern California Clinical Research, Orange County Retina Medical Group, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Santa Ana right now?

The largest active categories in Santa Ana are Diabetes & metabolic (8), Eye & vision (7), Neurology & pain (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

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Related healthcare resources in California

Trials by condition in Santa Ana