Paid Clinical Trials in San Jose, CA
As of August 2026, 80 paid clinical trials are recruiting in San Jose, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
San Jose offers studies at sites including Kaiser Permanente-Santa Teresa-San Jose for conditions such as Asthma, Major Depressive Disorder, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in San Jose
Trials by drug in San Jose
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70 clinical trials
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
A Study of NTX-1472 in Social Anxiety Disorder
A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Computer-Assisted Hair Restoration Study Using ARTAS System
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
E-Mindfulness Approaches for Living After Breast Cancer
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
Top Research Study Locations in San Jose
Researchers run research studies in San Jose, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Kaiser Permanente-Santa Teresa-San Jose | Breast Cancer, Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 | 32 |
| Stanford Cancer Center South Bay | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 11 |
| Lumos Clinical Research Center | Migraine, Episodic Migraine, Migraine Prophylaxis | 4 |
| Lumos Clinical Research Center | Major Depressive Disorder, Schizophrenia, Chronic Migraine | 3 |
| 3003 North First Street #221 | Extraocular Muscle Dysfunction, Graves Ophthalmopathy, Ocular Motility Disorders | 2 |
| Kaiser Permanente | Barrett Esophagus, Barretts Esophagus With Dysplasia, Cardiovascular Diseases | 2 |
| Kaiser Permanente San Jose | Clostridioides Difficile Associated Disease, Lumbar Spinal Stenosis | 2 |
| Neurocrine Clinical Site | Major Depressive Disorder | 2 |
| Prodigy Psychiatric Group | Attention Deficit Disorder (ADD), Attention Deficit Disorder With Hyperactivity (ADHD), Attention Deficit Hyperactivity Disorder (ADHD) | 2 |
| Vanda Investigational Site | Major Depressive Disorder (MDD), Nausea and Vomiting, Obesity | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, NASH - Nonalcoholic Steatohepatitis | 1 |
| Aligos Investigational Site | Chronic Hepatitis B Infection | 1 |
| Allergy and Asthma Associates of Santa Clara Valley Research Center | Asthma | 1 |
| Autobahn | Major Depressive Disorder | 1 |
| Enveda Investigative Site | Asthma | 1 |
| Kaiser Permanente - San Jose Medical Center | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Kaiser Permanente San Jose Emergency Department | Heart Failure | 1 |
| Kaiser Permanente Skyport Medical Offices | Primary IgA Nephropathy | 1 |
| Le's Aesthetics | Androgenic Alopecia | 1 |
| Lumos Clinical Research Center LLC | Depressive Disorder, Major | 1 |
| Ngoc Nguyen M.D. | Glaucoma, Glaucoma, Open Angle, Normal Tension Glaucoma (NTG) | 1 |
| Planned Parenthood Mar Monte | Contraception | 1 |
| Retension Clinical Site | Uncontrolled Hypertension | 1 |
| SOAR Clinical Study Site | Social Anxiety Disorder (SAD) | 1 |
| San Jose Clinical Trials, LLC | Type 1 Diabetes | 1 |
Active & Upcoming Studies in San Jose (2026)
Recruiting trials in San Jose grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (38 active studies)
- Distance-Based Exercise to Preserve Function and Prevent Disability · Alliance for Clinical Trials in Oncology
- Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial · Phase 3 · Alliance for Clinical Trials in Oncology
Neurology & pain (5 active studies)
- A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years · Phase 3 · AbbVie
- Long-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With Migraine · Phase 3 · AbbVie
Diabetes & metabolic (4 active studies)
- A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use · Phase 3 · Vanda Pharmaceuticals
- SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes · Phase 2 · SAb Biotherapeutics, Inc.
Mental health & behavior (3 active studies)
- A Study of NTX-1472 in Social Anxiety Disorder · Phase 2 · Newleos Therapeutics, Inc.
- Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU) · Bristol-Myers Squibb
Cardiovascular (3 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension · Phase 2 · Retension Pharmaceuticals. Inc.
HIV / STI (1 active study)
Eye & vision (1 active study)
- DSLT in Normal Tension Glaucoma (NTG) Asian Eyes · Ngoc Nguyen Inc.
Common conditions studied in San Jose
- Asthma (4 active studies)
- Major Depressive Disorder (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Breast Cancer (3 active studies)
- Lung Non-Small Cell Carcinoma (3 active studies)
- Stage IIIB Lung Cancer AJCC v8 (3 active studies)
Leading research sponsors in San Jose
- National Cancer Institute (NCI)
- NRG Oncology
- Alliance for Clinical Trials in Oncology
- SWOG Cancer Research Network
- AbbVie
Frequently asked questions
How many paid clinical trials are currently recruiting in San Jose?
There are approximately 80 recruiting clinical trials in San Jose, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Jose pay participants?
Most recruiting trials in San Jose compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Jose?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Jose?
The most common conditions under active study in San Jose include Asthma (4), Major Depressive Disorder (4), Anatomic Stage II Breast Cancer AJCC v8 (3), Breast Cancer (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Jose?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Jose on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Jose?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Jose?
Recruiting research sites in San Jose include Kaiser Permanente-Santa Teresa-San Jose, Stanford Cancer Center South Bay, Lumos Clinical Research Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Jose right now?
The largest active categories in San Jose are Cancer & tumors (38), Neurology & pain (5), Diabetes & metabolic (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.