Paid Clinical Trials in Newport Beach, CA
As of August 2026, 183 paid clinical trials are recruiting in Newport Beach, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Newport Beach offers studies at sites including Hoag Memorial Hospital Presbyterian for conditions such as Breast Cancer, Breast Neoplasms, Advanced Solid Tumor, Asthma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Newport Beach
Trials by drug in Newport Beach
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Newly added in Newport Beach
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
SLR-108 PET Imaging in Subjects With Metastatic Solid Tumors
A Study of BL1332 on Capsaicin-Induced Ocular Pain in Healthy Trial Participants
Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study
A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study
A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.
171 clinical trials
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
Top Research Study Locations in Newport Beach
Researchers run research studies in Newport Beach, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Hoag Memorial Hospital Presbyterian | Advanced Solid Tumor, Breast Cancer, Non Small Cell Lung Cancer | 52 |
| USC Norris Oncology/Hematology-Newport Beach | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 15 |
| Hoag Memorial Hospital | Type 1 Diabetes, Advanced Solid Tumor, Advanced Solid Tumors | 10 |
| NewportNativeMD, Inc. | Asthma, Diffuse Cutaneous Systemic Sclerosis, Interstitial Lung Disease | 6 |
| Eye Research Foundation | Dry Eye Disease (DED), Macular Edema, Moderate to Severe Glabellar Lines | 6 |
| City of Hope Newport Beach | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 5 |
| City of Hope at Newport Beach Fashion Island | Lung Non-Small Cell Carcinoma, Metastatic Pancreatic Adenocarcinoma, Multiple Myeloma | 5 |
| Hoag Family Cancer Institute | Advanced Metastatic Castration Resistant Prostate Cancer, Advanced NET of GI Origin, Advanced or Metastatic Solid Tumors | 5 |
| Hoag | Benign Liver Tumor, Genetic Predisposition, Liver Neoplasms | 5 |
| Hoag Hospital | Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder), Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder) | 4 |
| Hoag Hospital Newport Beach | Anaplastic Lymphoma Kinase-positive, Crohn's Disease, Non-small Cell Lung Cancer | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| GSK Investigational Site | Asthma, Pulmonary Disease, Chronic Obstructive | 2 |
| Hoag Gynecologic Oncology | Cervical Cancer, Endometrioid Ovarian Cancer, Fallopian Tube Cancer | 2 |
| Hoag Memorial Hospital Presbyterian;Hoag Center for Research and Education | Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 2 |
| Radin Cardiovascular Medical Group | Heart Failure, Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | 2 |
| University Dermatology Trials | Dermatitis Atopic | 2 |
| Newport Native MD, Inc. | COPD, Asthma | 2 |
| Amy Patel Jain MD | Thyroid Eye Disease | 1 |
| CREST-XT | Open-angle Glaucoma (OAG) | 1 |
| California Orbital Consultants | Non-Arteritic Anterior Ischemic Optic Neuropathy | 1 |
| Crinetics Study Site | Neuroendocrine Neoplasm, Neuroendocrine Tumors, SST2-positive Neuroendocrine Neoplasms | 1 |
| Donald S Mowlds, MD A Professional Corporation | Capsular Contracture Associated With Breast Implant, Capsular Contracture Grade III, Capsular Contracture Grade IV | 1 |
| Eye Research Foundation Inc. | Glaucoma, Open-Angle, Ocular Hypertension | 1 |
| Eye research foundation, Inc. | Ocular Hypertension (OH), Primary Open Angle Glaucoma (POAG) | 1 |
Active & Upcoming Studies in Newport Beach (2026)
Recruiting trials in Newport Beach grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (83 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- Study of Oral MRT-2359 With Apalutamide in Prostate Cancer · Phase 2 · Monte Rosa Therapeutics, Inc
Eye & vision (10 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
Cardiovascular (9 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention · Phase 4 · Duke University
Diabetes & metabolic (7 active studies)
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
- A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study) · Aqua Medical, Inc.
Neurology & pain (5 active studies)
Vaccines (1 active study)
- Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. · Phase 2 · Vasomune Therapeutics, Inc.
Mental health & behavior (1 active study)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
Pediatric (1 active study)
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
Common conditions studied in Newport Beach
- Breast Cancer (6 active studies)
- Breast Neoplasms (6 active studies)
- Advanced Solid Tumor (5 active studies)
- Asthma (5 active studies)
- Non-small Cell Lung Cancer (5 active studies)
- Non Small Cell Lung Cancer (4 active studies)
Leading research sponsors in Newport Beach
- AstraZeneca
- National Cancer Institute (NCI)
- City of Hope Medical Center
- SWOG Cancer Research Network
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Newport Beach?
There are approximately 183 recruiting clinical trials in Newport Beach, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Newport Beach pay participants?
Most recruiting trials in Newport Beach compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Newport Beach?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Newport Beach?
The most common conditions under active study in Newport Beach include Breast Cancer (6), Breast Neoplasms (6), Advanced Solid Tumor (5), Asthma (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Newport Beach?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Newport Beach on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Newport Beach?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Newport Beach?
Recruiting research sites in Newport Beach include Hoag Memorial Hospital Presbyterian, USC Norris Oncology/Hematology-Newport Beach, Hoag Memorial Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Newport Beach right now?
The largest active categories in Newport Beach are Cancer & tumors (83), Eye & vision (10), Cardiovascular (9). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.