Paid Clinical Trials in Santa Barbara, CA
As of August 2026, 68 paid clinical trials are recruiting in Santa Barbara, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Santa Barbara offers studies at sites including Ridley-Tree Cancer Center for conditions such as Basic Science: Visual Attention in Healthy Participants, Fallopian Tube Cancer, Neovascular Age-Related Macular Degeneration (nAMD), Prostate Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Santa Barbara
Trials by drug in Santa Barbara
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Newly added in Santa Barbara
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
57 clinical trials
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
Galleri® in the Medicare Population.
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System
Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study
Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)
A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01
Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
Top Research Study Locations in Santa Barbara
Researchers run research studies in Santa Barbara, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Ridley-Tree Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8 | 11 |
| Sansum Clinic | Carcinoma, Non-Small-Cell Lung, Prostate Cancer, Acinar Cell Carcinoma | 10 |
| Santa Barbara Cottage Hospital | Acute Myeloid Leukemia, Adrenal Gland Pheochromocytoma, Aortic Stenosis | 10 |
| Sansum Diabetes Research Institute | Type 2 Diabetes Mellitus, Diabetes (DM), Diabetes (Insulin-requiring, Type 1 or Type 2) | 5 |
| University of California, Santa Barbara | Basic Science: Visual Attention in Healthy Participants, Basic Science: Neural Representations of Location, Attention | 5 |
| California Retina Consultants | Geographic Atrophy Secondary to Age-related Macular Degeneration, Neovascular Age-Related Macular Degeneration (nAMD), Neovascular Age-related Macular Degeneration | 4 |
| California Retina Consultants CRC | Diabetic Retinopathy, DR, Neovascular Age-related Macular Degeneration, Wet Macular Degeneration | 2 |
| Adverum Clinical | Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD | 1 |
| California Retina Consultants (CRC) | Neovascular Age-Related Macular Degeneration (nAMD) | 1 |
| California Retina Consultants- Santa Barbara | Diabetic Retinopathy, NPDR - Non Proliferative Diabetic Retinopathy | 1 |
| Cancer Center of Santa Barbara | Malignant Neoplasm | 1 |
| Central Valley Surg Ctr | Lumbar Spinal Stenosis | 1 |
| Coastal Surgery Center | Lumbar Spinal Stenosis | 1 |
| Cognixion | ALS (Amyotrophic Lateral Sclerosis) | 1 |
| Cognixion HQ | ALS (Amyotrophic Lateral Sclerosis), SCI - Spinal Cord Injury, Stroke | 1 |
| Cottage Health Research Institute | Aneurysm, Brain, Stroke, Thromboses, Intracranial | 1 |
| Cottage Health System - Santa Barbara Pulmonary Associates | Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension, Pulmonary Hypertension | 1 |
| Exelixis Clinical | Clear Cell Renal Cell Carcinoma (ccRCC), Colorectal Cancer (CRC), Drug-Drug Interaction (DDI) | 1 |
| SCRI - Sansum Clinic | Endometrioid Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer | 1 |
| Samsun Clinic - Ridley-Tree Cancer Center | Urinary Bladder Neoplasms, Urothelial Cancer | 1 |
| Sansum Clinic (Ridley Tree) | Lung Neoplasm Malignant | 1 |
| Sansum Clinic, Sutter Health | Diabetes, Nutrition | 1 |
| Santa Barbara Outpatient Surgery Center LLC | Lumbar Spinal Stenosis | 1 |
| Sutter Sansum Clinic | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Sutter Valley Hospitals Santa Barbara | Cancer | 1 |
Active & Upcoming Studies in Santa Barbara (2026)
Recruiting trials in Santa Barbara grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (30 active studies)
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
Cardiovascular (8 active studies)
- A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH) · Phase 3 · Insmed Incorporated
- Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) · Phase 3 · Insmed Incorporated
Diabetes & metabolic (6 active studies)
- MiniMed Fit Payload Wear Pediatric Study · Medtronic MiniMed, Inc.
- Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System · Insulet Corporation
Eye & vision (6 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study · Phase 3 · Ocular Therapeutix, Inc.
Neurology & pain (3 active studies)
- Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple Vision Pro · Cognixion
- Stroke Thrombectomy and Aneurysm Registry · Medical University of South Carolina
Pediatric (1 active study)
- MiniMed Fit Payload Wear Pediatric Study · Medtronic MiniMed, Inc.
Common conditions studied in Santa Barbara
- Basic Science: Visual Attention in Healthy Participants (3 active studies)
- Fallopian Tube Cancer (3 active studies)
- Neovascular Age-Related Macular Degeneration (nAMD) (3 active studies)
- Prostate Cancer (3 active studies)
- Pulmonary Arterial Hypertension (3 active studies)
- Pulmonary Hypertension (3 active studies)
Leading research sponsors in Santa Barbara
- NRG Oncology
- University of California, Santa Barbara
- AbbVie
- Children's Oncology Group
- Novartis Pharmaceuticals
Frequently asked questions
How many paid clinical trials are currently recruiting in Santa Barbara?
There are approximately 68 recruiting clinical trials in Santa Barbara, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Santa Barbara pay participants?
Most recruiting trials in Santa Barbara compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Santa Barbara?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Santa Barbara?
The most common conditions under active study in Santa Barbara include Basic Science: Visual Attention in Healthy Participants (3), Fallopian Tube Cancer (3), Neovascular Age-Related Macular Degeneration (nAMD) (3), Prostate Cancer (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Santa Barbara?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Santa Barbara on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Santa Barbara?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Santa Barbara?
Recruiting research sites in Santa Barbara include Ridley-Tree Cancer Center, Sansum Clinic, Santa Barbara Cottage Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Santa Barbara right now?
The largest active categories in Santa Barbara are Cancer & tumors (30), Cardiovascular (8), Diabetes & metabolic (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.