Amygdala-Prefrontal in Fear Extinction
for Fear Extinction
1 location in St Louis
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+
Code: NCT07800455·Recruiting·Listed Sep 2, 2026
Clinical Trials at Washington University School of Medicine
As of September 2026, 429 paid clinical trials are recruiting at Washington University School of Medicine, located at Washington University School of Medicine, 1 Children's Pl, St. Louis, MO 63110, phone (314) 454-6215 in St Louis, Missouri. Active studies at this site cover conditions such as Breast Cancer, Prostate Cancer and Colorectal Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in St Louis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study)
for Healthy Adult
1 location in St Louis
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07800481·EARLY_Phase 1·Recruiting·Listed Sep 2, 2026
A Trial to Assess the Efficacy and Safety of Engasertib in Participants With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT)
for Hereditary Hemorrhagic Telangiectasia
Sites in St Louis +3 more locations
Sponsor: Vaderis Therapeutics AG
Sex: All·Age: 18+
Code: NCT07743671·Phase 3·Recruiting·Listed Aug 4, 2026
432 clinical trials at Washington University School of Medicine
·Clear filters· Get a weekly email when new trials open in St Louis, MO.
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
for Moderate to Severe Chronic Obstructive Pulmonary Disease
Drug: PF-07275315
Sites in St Louis +60 more locations
Sponsor: Pfizer
Sex: All·Age: 35 - 80
Code: NCT07363694·Phase 2, Phase 3·Recruiting·Listed Jan 2026
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
for Clostridoides Difficile Associated Disease
Sites in St Louis +139 more locations
Sponsor: Pfizer
Sex: All·Age: 65+·Accepts healthy volunteers
Code: NCT07282665·Phase 3·Recruiting·Listed Dec 2025
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
for CRC (Colorectal Cancer)
Drug: Bevacizumab
Sites in St Louis, Columbia +73 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT07284849·Phase 3·Recruiting·Listed Dec 2025
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
for Breast Neoplasms
Sites in St Louis +31 more locations
Sponsor: Eli Lilly and Company
Sex: Female·Age: 18+
Code: NCT07287098·Phase 2·Recruiting·Listed Dec 2025
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
for Squamous Cell Carcinoma of Head and Neck
Drug: Amivantamab
Sites in St Louis +46 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT07276399·Phase 3·Recruiting·Listed Dec 2025
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
for Carcinoma, Transitional Cell
Sites in St Louis, Springfield +60 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07218380·Phase 3·Recruiting·Listed Oct 2025
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
for Crohn's Disease
Drug: Duvakitug
Sites in St Louis, Liberty +123 more locations
Sponsor: Sanofi
Sex: All·Age: 16 - 80
Code: NCT07184931·Phase 3·Recruiting·Listed Sep 2025
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
for Triple Negative Breast Cancer
Sites in St Louis +120 more locations
Sponsor: Gilead Sciences
Sex: All·Age: 18+
Code: NCT05633654·Phase 3·Recruiting·Listed Dec 2022
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
for Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Drug: Coramitug
Sites in St Louis, Kansas City +60 more locations
Sponsor: Novo Nordisk A/S
Sex: All·Age: 18+
Code: NCT07207811·Phase 3·Recruiting·Listed Oct 2025
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
for Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Sites in St Louis, Springfield +123 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06667076·Phase 2·Recruiting·Listed Oct 2024
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
for Melanoma
Sites in St Louis +90 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT06246916·Phase 3·Recruiting·Listed Feb 2024
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
for Endometrial Cancer
Sites in St Louis +67 more locations
Sponsor: Genmab
Sex: Female·Age: 18+
Code: NCT07166094·Phase 3·Recruiting·Listed Sep 2025
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
for Crohn's Disease
Drug: Tulisokibart
Sites in St Louis, Liberty +69 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 16 - 80
Code: NCT06430801·Phase 3·Recruiting·Listed May 2024
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
for Colorectal Neoplasms
Drug: Amivantamab
Sites in St Louis +67 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06750094·Phase 3·Recruiting·Listed Dec 2024
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
for Colorectal Neoplasms
Drug: Amivantamab
Sites in St Louis +80 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06662786·Phase 3·Recruiting·Listed Oct 2024
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo
for NonSegmental Vitiligo
Drug: Ruxolitinib
Sites in St Louis, Kansas City +67 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 2 - 11
Code: NCT06548360·Phase 3·Recruiting·Listed Aug 2024
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
for Clostridium Difficile
Sites in St Louis, Weldon Spring +54 more locations
Sponsor: Vedanta Biosciences, Inc.
Sex: All·Age: 12+
Code: NCT06237452·Phase 3·Recruiting·Listed Feb 2024
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
for Breast Neoplasms
Sites in St Louis, Kansas City +38 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06312176·Phase 3·Recruiting·Listed Mar 2024
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
for Chronic Lymphocytic Leukemia
Sites in St Louis +46 more locations
Sponsor: BeOne Medicines
Sex: All·Age: 18+
Code: NCT06973187·Phase 3·Recruiting·Listed May 2025
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
for Diabetes Mellitus, Type 2
Sites in St Louis +122 more locations
Sponsor: Cleerly, Inc.
Sex: All·Age: 55+·Accepts healthy volunteers
Code: NCT06112418·Recruiting·Listed Nov 2023
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
for Alzheimers Disease
Drug: Trontinemab
Sites in St Louis +34 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 50 - 90
Code: NCT07169578·Phase 3·Recruiting·Listed Sep 2025
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
for Ulcerative Colitis
Drug: Tofacitinib
Sites in St Louis, Liberty +35 more locations
Sponsor: Takeda
Sex: All·Age: 18 - 65
Code: NCT06095128·Phase 4·Recruiting·Listed Oct 2023
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
for Mantle Cell Lymphoma
Drug: Sonrotoclax
Sites in St Louis +40 more locations
Sponsor: BeOne Medicines
Sex: All·Age: 18+
Code: NCT06742996·Phase 3·Recruiting·Listed Dec 2024
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease
for Crohn's Disease
Drug: Ustekinumab
Sites in St Louis, Liberty +39 more locations
Sponsor: Takeda
Sex: All·Age: 18 - 70
Code: NCT06045754·Phase 4·Recruiting·Listed Sep 2023
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
for Non-Small Cell Lung Cancer
Sites in St Louis +25 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07100080·Phase 2, Phase 3·Recruiting·Listed Aug 2025
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
for Focal Epilepsy
Drug: BHV-7000
Sites in St Louis +44 more locations
Sponsor: Biohaven Therapeutics Ltd.
Sex: All·Age: 18 - 75
Code: NCT06132893·Phase 2, Phase 3·Recruiting·Listed Nov 2023
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
for Multiple Myeloma
Sites in St Louis +27 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT05201781·Phase 4·Recruiting·Listed Jan 2022
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
for Ovarian Cancer
Sites in St Louis +34 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: Female·Age: 18+
Code: NCT06824467·Phase 3·Recruiting·Listed Feb 2025
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
for Low Grade Serous Ovarian Cancer
Drug: Avutometinib
Sites in St Louis +35 more locations
Sponsor: Verastem, Inc.
Sex: Female·Age: 18+
Code: NCT06072781·Phase 3·Recruiting·Listed Oct 2023
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
for Extensive-stage Small-cell Lung Cancer
Sites in St Louis +33 more locations
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT06712355·Phase 3·Recruiting·Listed Dec 2024
A Phase 1/1b Study of IAM1363 in HER2 Cancers
for HER2 Mutation-Related Tumors
Sites in St Louis, Kansas City +27 more locations
Sponsor: Iambic Therapeutics, Inc
Sex: All·Age: 18+
Code: NCT06253871·Phase 1·Recruiting·Listed Feb 2024
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Sites in St Louis, Columbia +39 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 12+
Code: NCT06338995·Phase 3·Recruiting·Listed Apr 2024
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
for Ulcerative Colitis
Drug: Tirzepatide
Sites in St Louis +36 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 70
Code: NCT06937086·Phase 3·Recruiting·Listed Apr 2025
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
for Crohn's Disease
Drug: Tirzepatide
Sites in St Louis +34 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 70
Code: NCT06937099·Phase 3·Recruiting·Listed Apr 2025
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
for Carcinoma, Non-small-Cell Lung
Drug: Amivantamab
Sites in St Louis +13 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT05498428·Phase 2·Recruiting·Listed Aug 2022
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
for Asthma
Drug: PF-07275315
Sites in St Louis +34 more locations
Sponsor: Pfizer
Sex: All·Age: 18 - 70
Code: NCT06977581·Phase 2·Recruiting·Listed May 2025
FOG-001 in Locally Advanced or Metastatic Solid Tumors
for Cancer
Sites in St Louis +29 more locations
Sponsor: Parabilis Medicines, Inc.
Sex: All·Age: 18+
Code: NCT05919264·Phase 1, Phase 2·Recruiting·Listed Jun 2023
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
for AML
Sites in St Louis +35 more locations
Sponsor: Kura Oncology, Inc.
Sex: All·Age: 18+
Code: NCT06001788·Phase 1·Recruiting·Listed Aug 2023
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
for Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Sites in St Louis +36 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18 - 75
Code: NCT05519475·Phase 2·Recruiting·Listed Aug 2022
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
for Pulmonary Hypertension Due to Lung Diseases and Hypoxia
Sites in St Louis +69 more locations
Sponsor: United Therapeutics
Sex: All·Age: 18+
Code: NCT06388421·Recruiting·Listed Apr 2024
Common conditions studied in St Louis
- Breast Cancer (37 active studies)
- Prostate Cancer (32 active studies)
- Colorectal Cancer (23 active studies)
- Advanced Solid Tumor (21 active studies)
- Acute Myeloid Leukemia (20 active studies)
- Alzheimer Disease (20 active studies)
Leading research sponsors in St Louis
- Washington University School of Medicine
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in St Louis?
There are approximately 1,422 recruiting clinical trials in St Louis, Missouri listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in St Louis pay participants?
Most recruiting trials in St Louis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in St Louis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in St Louis?
The most common conditions under active study in St Louis include Breast Cancer (37), Prostate Cancer (32), Colorectal Cancer (23), Advanced Solid Tumor (21), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in St Louis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in St Louis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in St Louis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in St Louis?
Recruiting research sites in St Louis include Washington University School of Medicine, Washington University, Washington University in St. Louis, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in St Louis right now?
The largest active categories in St Louis are Cancer & tumors (544), Neurology & pain (100), Cardiovascular (74). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Washington University School of Medicine?
Washington University School of Medicine is located at Washington University School of Medicine, 1 Children's Pl, St. Louis, MO 63110. Use the Google Maps link in the intro above to get directions.
How do I contact Washington University School of Medicine?
You can reach Washington University School of Medicine by phone at (314) 454-6215. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
Other cities in Missouri
Kansas City, MO(467)Columbia, MO(229)Springfield, MO(124)City of Saint Peters, MO(91)Cape Girardeau, MO(82)Creve Coeur, MO(75)Lee's Summit, MO(67)Farmington, MO(61)Sainte Genevieve, MO(61)Sullivan, MO(60)Saint Joseph, MO(54)Chesterfield, MO(50)Osage Beach, MO(45)Joplin, MO(39)Ballwin, MO(38)Rolla, MO(37)Bolivar, MO(33)Saint Charles, MO(31)Washington, MO(28)Branson, MO(26)Sunset Hills, MO(21)Jefferson City, MO(20)Liberty, MO(20)Bridgeton, MO(17)Hazelwood, MO(11)Hannibal, MO(10)O'Fallon, MO(9)Independence, MO(8)North Kansas City, MO(8)Town and Country, MO(6)Florissant, MO(5)Kirksville, MO(5)Fenton, MO(3)Weldon Spring, MO(3)Chillicothe, MO(2)Saint Loius, MO(2)Annapolis, MO(1)Belton, MO(1)Bethany, MO(1)Carrollton, MO(1)Carthage, MO(1)Clinton, MO(1)Des Peres, MO(1)Excelsior Springs, MO(1)Festus, MO(1)Frontenac, MO(1)Kansa City, MO(1)Lake Saint Louis, MO(1)Lebanon, MO(1)Louis, MO(1)Manchester, MO(1)Marshall, MO(1)Overland, MO(1)Overland Park, MO(1)Ozark, MO(1)Poplar Bluff, MO(1)Raymore, MO(1)Raytown, MO(1)Roseville, MO(1)Troy, MO(1)