Anxiety Clinical Trials

Recruiting anxiety studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat anxiety. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting anxiety studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting anxiety trials

Within

Whole-Body Hyperthermia for Mood and Anxiety Disorders

for Postpartum Depression

1 site in New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06144294

INNOV5-MH-MAROC: Integrated Mental Health Care for Adolescents and Adults in Primary Care Centers and Schools in Morocco

for Depression in Adolescence

Sponsor: Swiss Medical Academy Maroc

Sex: All·Age: 12+

Code: NCT07258095

Simulation-Based Patient Education to Address Radiotherapy-Related Anxiety in Cancer Patients (ARAISE)

for Neoplasms

Sponsor: University Medical Center Goettingen

Sex: All·Age: 18+

Code: NCT07721246

Mental Health INtervention With Digital APPlications (MIND-APP): Randomized Controlled Researcher Blinded Trial Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health Apps

for Anxiety

Sponsor: University Hospital, Akershus

Sex: All·Age: 16+

Code: NCT07627204

Virtual Intervention for Behavioral Health in Emerging Adults; "VIBE in the Parks"

for Anxiety

Sponsor: University of Illinois at Chicago

Sex: All·Age: 13 - 24

Code: NCT07539636

Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled Trial

for Emotional Disorders

Sponsor: Universitat Jaume I

Sex: All·Age: 18 - 70

Code: NCT07051148

Pivotal U.S. Clinical Validation of AI-COA® for Depression and Anxiety

for Depression Disorders

1 site in Houston

Sponsor: Deliberate Solutions Inc.

Sex: All·Age: 18 - 65

Code: NCT07279038

Community Health Worker Implementation of Transdiagnostic Evidence-based Mental Health Intervention for Spanish-speaking Latine Parents

for Depression

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07390630

Implementation of a Just-In-Time Adaptive Intervention for Adolescent Anxiety

for Anxiety

Sponsor: Trustees of Dartmouth College

Sex: All·Age: 13 - 17

Code: NCT06946823

Quantifying Multi-step Avoidance in Anxiety

for Anxiety

2 sites in Atlanta

Sponsor: Emory University

Sex: All·Age: 22 - 55·Accepts healthy volunteers

Code: NCT07203027

Personalizing Mental Health Treatment for Youth and Families

for Anxiety

Sponsor: University of Oregon

Sex: All·Age: 5 - 15

Code: NCT07425366

Comparative Effects of Four Brief Breathwork and Mindfulness Interventions on Anxiety and Psychological Flexibility: A 4-Arm RCT

for Anxiety

Sponsor: Valencian International University (VIU)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07621042

Immersive VR to Reduce Stress, Anxiety, and Pain During PICC/Midline Placement

for Vasoconstriction

Sponsor: diana garcia

Sex: All·Age: 18+

Code: NCT07696156

Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0)

for Diagnoses of Depression

2 sites incl. Indianapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07645274

The Role of Virtual Reality During Regional Anesthesia

for Anxiety

1 site in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT04163809

Qualitative Study of Student Financial Insecurity and Psychiatry

for Depressive Disorder

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT07719816

Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children

for Anxiety

Sponsor: Ege University

Sex: All·Age: 6 - 12

Code: NCT06955338

Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings

for Autism Spectrum Disorder

1 site in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 11 - 17

Code: NCT07755137

Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum

for Depression

1 site in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 55

Code: NCT07801079

Supporting Families in the ICU

for Anxiety

2 sites incl. San Francisco

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07228299

Adult ADHD Symptoms, Depression, Anxiety, and Academic Performance in Medical Students

for Attention Deficit Hyperactivity Disorder

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07803224

Comparing Radiotherapy Immobilization Systems for Anxious HNC Patients

for Head and Neck Cancer

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 18+

Code: NCT06257121

A Trial of the Safety and Tolerability of SEP-363856 in Adults With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18+

Code: NCT07786454·Phase 3

Arousal-related Memory Following Theta Burst Stimulation.

for Anxiety

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07565194

Effectiveness of a Sound Bowl Meditation on Caregiver Stress and Anxiety

for Stress

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07626320

Ecological Momentary Intervention (E-Breathing) to Reduce Psychological Distress in Adolescents

for Psychological Distress

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 11 - 17

Code: NCT07717112

AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study

for Feasibility Studies

1 site in Knoxville

Sponsor: The University of Tennessee, Knoxville

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07768670

Apply to this trial

Deaf CBT-TS to Reduce Suicide Risk

for Depression - Major Depressive Disorder

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT07279363

Pre-operative Interventional Paramedical Consultation: What About the Implantable Device?

for Anxiety

Sponsor: University Hospital, Grenoble

Sex: All·Age: 18+

Code: NCT07559981

Feasibility and Preliminary Outcomes of the Brave Elephant Program: A Single-Arm Pretest-Posttest Study

for Anxiety

Sponsor: ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida

Sex: All·Age: 3 - 6·Accepts healthy volunteers

Code: NCT07567820

Active vs. Passive VR During Office-based ENT Procedures

for Pain

1 site in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT07599826

Student Precarity and Psychiatry

for Depressive Disorder, Major

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07618208

Remimazolam Versus Dexmedetomidine for Sedation During Neuraxial

for Pregnant People

1 site in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female·Age: 18+

Code: NCT07651956·Phase 4

A Virtual Clinical Trial to Examine the Effect of Magnesium Choline Citrate on Cognitive Function and Anxiety in Healthy Adolescents and Adults

for Cognitive Function

Sponsor: Nutrisol, LLC

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT07685613

Prognosis of Epilepsy With Post-traumatic Stress Disorder and Surgery

for Epilepsies, Focal

Sponsor: Assistance Publique Hopitaux De Marseille

Sex: All·Age: 18+

Code: NCT07718542

An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

for Excessive Gestational Weight Gain

2 sites in San Diego

Sponsor: San Diego State University

Sex: Female·Age: 18+

Code: NCT07792837

Apply to this trial

Virtual Group Therapy for IBD Patients With Anxiety and Depression

for Crohn's Disease (CD)

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07796568

TOUCHminds: Help-seeking in Adolescents With Anxiety

for Anxiety Symptoms

Sponsor: Aveiro University

Sex: All·Age: 15 - 17·Accepts healthy volunteers

Code: NCT07366580

Study on Mental Health Promoting Effects of Natural Psychotherapy for Adolescents

for Anxiety Disorders

Sponsor: Beijing HuiLongGuan Hospital

Sex: All·Age: 7 - 18·Accepts healthy volunteers

Code: NCT07639476

2D:4D Ratio in Relation to Anxiety and Stress Among Anesthesiology Residents

for Anxiety

Sponsor: Ain Shams University

Sex: All·Age: 20 - 35

Code: NCT07757971

proState Cancer Health Education to pRomote Early sreENing Uptake (SCREEN): A Pilot Randomised Control Trial

for Anxiety

Sponsor: Teesside University

Sex: Male·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07800390

The Impact of Dexmedetomidine Nasal Spray on Perioperative Anxiety in Neurosurgical Patients

for Anxiety

Sponsor: Beijing Tiantan Hospital

Sex: All·Age: 18 - 75

Code: NCT07801014

AcceXible Speech-Based Screening for Depression and Anxiety in University Students (UAQ, Mexico)

for Depression - Major Depressive Disorder

Sponsor: Accexible

Sex: All·Age: 16 - 25·Accepts healthy volunteers

Code: NCT07578142

Mindfulness in High Risk Pregnancies

for Stress

Sponsor: University of Alberta

Sex: Female·Age: 18+

Code: NCT04496115

Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial

for Metabolic Syndrome

Sponsor: University of Zadar

Sex: All·Age: 20+·Accepts healthy volunteers

Code: NCT07314957

Effect of cTBS on Startle and TMS-evoked BOLD

for Anxiety

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07415772

Single Arm, Monocentric, Pilot Feasibility Study on an Interactive Virtual Reality Program in 20 Complex In-clinic Palliative Care Patients

for Palliative Care

Sponsor: University Hospital, Strasbourg, France

Sex: All·Age: 18+

Code: NCT07545928

MyFILM: A Pilot Study for Social-Emotional Learning in Clinical Youth

for Mood Disorders

Sponsor: Mark Sinyor

Sex: All·Age: 9 - 12

Code: NCT07708168

Latin Dance and Psychological Health in Primary School Children

for Loneliness

Sponsor: Xu Shuishui

Sex: All·Age: 6 - 12·Accepts healthy volunteers

Code: NCT07755995

The Effect of Mindfulness in Inflammation Markers (IL-6, TNF-A, CRP and Cortisol) Among Survivors of Tidal Flooding in Sayung Demak

for Psychological Stress

Sponsor: Natalia Dewi Wardani, MD

Sex: All·Age: 18 - 60

Code: NCT07790055

The Effect of Mindfulness in Inflammation Markers (MLR, NLR, PLR), Stress, Anxiety, and Depression Rate Among Survivors of Tidal Flooding in Sayung Demak

for Psychological Stress

Sponsor: Natalia Dewi Wardani, MD

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07796919

Reduction of Anxiety in People With Disabilities Through Dual Treatment: Digital CBT & NBHWC Coaching - A Randomized Clinical Trial

for Hearing Disability

4 sites incl. Dover

Sponsor: Toivoa Inc

Sex: All·Age: 22+

Code: NCT07140497

Buspirone for Anxiety in Autistic Youth

for Anxiety

Sponsor: Massachusetts General Hospital

Sex: All·Age: 7 - 17

Code: NCT07439042·Phase 4

A Study of a Mental Fitness Intervention for Anesthesiology Resident Wellbeing and Self-Compassion

for Wellness

2 sites in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07639827

LIFU for Chronic Pain and Generalized Anxiety Disorder

for Chronic Pain

1 site in Roanoke

Sponsor: Virginia Polytechnic Institute and State University

Sex: All·Age: 18 - 65

Code: NCT07686354

Dexmedetomidine-Esketamine Combination on Depression and Anxiety After Laparoscopic Ureteral Reconstruction

for Ureteral Stricture

Sponsor: Peking University First Hospital

Sex: All·Age: 18+

Code: NCT07753772·Phase 4

Continuous Theta Burst Stimulation for Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sponsor: Military Hospital 175

Sex: All·Age: 18 - 65

Code: NCT07770919

Impact of Play Interventions on Stress and Anxiety Using EEG and AI.

for Anxiety

Sponsor: Universidad Autonoma de Baja California

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07555158

Psilocybin-Assisted Therapy for Intergenerational Trauma

for Psychological Stress

1 site in New York

Sponsor: Rachel Yehuda

Sex: All·Age: 18+

Code: NCT06899165·Phase 2

Apply to this trial

Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students

for Stress

1 site in Tuscaloosa

Sponsor: University of Alabama, Tuscaloosa

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07415460

Apply to this trial

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Anxiety clinical trials — common questions

Are anxiety clinical trials free to join?

Yes. Participating in a anxiety clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a anxiety clinical trial?

Each anxiety study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a anxiety trial near me?

Use the location controls above. We'll show recruiting anxiety trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many anxiety trials are recruiting right now?

We're currently tracking roughly 241 recruiting anxiety trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Anxiety trials by city

Boston, MA Los Angeles, CA Chicago, IL Miami, FL Columbus, OH San Francisco, CA Birmingham, AL Madison, WI Tallahassee, FL Ann Arbor, MI Aurora, CO Cincinnati, OH

Related specialties

Psychiatry Mental health Behavioral health