Congenital heart disease Clinical Trials
Recruiting congenital heart disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.
Clinical trials study new ways to prevent, detect, or treat congenital heart disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting congenital heart disease studies with sites across the US; use the location tools to find ones near you.
What to expect
- Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
- Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
- No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.
Recruiting congenital heart disease trials
Exercise Prehabilitation in Congenital Heart Disease
Tailored MgSO4 Supplementation to Reduce Complications in Pediatric Heart Surgery
Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial Prospective
Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due to Chronic Diseases Such as Congenital Heart Disease, Chronic Inflammatory Bowel Disease, Celiac Disease and Rheumatic Disorders
Interoceptive Intervention for Congenital Heart Disease
Autus Valve Continued Access Study (CAS)
Exergame-Based Physical Activity Promotion for Children and Adolescents With Congenital Heart Disease
Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach
Chest X-Rays for Early Detection of Congenital Heart Disease in Newborns
LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients
Longitudinal Validation of CIRC Technologies
"Effects of High-Calorie Diets VS High-Calorie Formulas on Weight Gain in Children With Congenital Heart Disease "
Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care (COMPAXE-HNF)
Perioperative Lidocaine for Lung Protection in Infants Undergoing Cardiac Surgery
Design and Application of a Home Care WeChat Mini-Program for Children After Congenital Heart Disease Surgery
Non-Invasive Electrocardiographic Imaging for Personalized Arrhythmia Care in Congenital Heart Disease
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
Assessment of Psychiatric Problems in Pre- and Post-Intervention in Patients With CHD
Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery
Congenital Heart Diseases and Developmental Assessment in Cholestatic Infants Under Two Years
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children
Implementation of an Accessible Healthcare Model (ACHD STRONG): Comparing Nurse and Physician Lead Healthcare Transition Education in a RE-AIM Framework
Calprotectin and Gut Disease Study
Effectiveness of High-Energy Density Enteral Nutrition for Enhancing Physical Growth and Cognitive Brain Development in Infants With Congenital Heart Disease
Parent Navigator Program (PNP) to Improve Outcomes in Latino/x Children and Parents
Prevalence of Liver Dysfunction in Pediatric Patients With Congenital Heart Disease at Assiut.
Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease
Prenatal Maternal Mental Health and Neurodevelopment in Congenital Heart Disease
Fontan Fitness Trial
SGLT2 Inhibition With Empagliflozin in Fontan Circulatory Failure
Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status Trial
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
Precision Medicine in the CICU: Identifying Proteomic Biomarkers
Antenatal Investigation of Fetuses With Complex Congenital Heart Defects Using multiOMICS
HFNC vs NIPPV Following Extubation
A Study of Hemodynamic Cardiopulmonary Exercise for CHD
Effect of Sacubitril-Valsartan on Cardiac Structure and Function
A Chinese Multicenter Study on Surgical Techniques and Outcomes Across the Lifespan in Congenital Heart Disease
Value of MRI in Congenital Heart Disease
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables
Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease
High Intensity Interval Training in Patients With a Right Ventricle to Pulmonary Artery Conduit
The Efficacy of Systematic Oral Feeding Education Program
PDA for Kidneys Study
Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children
Pregnancy in GUCH Patients
Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis
Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)
NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
Digital Health Promotion for Children With Congenital Heart Disease and Their Guardians
Improving Congenital Heart Disease Care
Neuro-cardiac Rehabilitation in Youth With Congenital Heart Disease (QUALINEUROREHAB)
Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD
iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease
Online Support 4 CHD Kids & Caregivers
A Comprehensive Registry Study of the Whole Life Cycle of Patients With CHD
Prognostic Model of Postnatal Circulation in Pulmonary Atresia-critical Stenosis With Intact Ventricular Septum
The Co-Op @ HeartWorks
The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study
Congenital heart disease clinical trials — common questions
Are congenital heart disease clinical trials free to join?
Yes. Participating in a congenital heart disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.
Who can join a congenital heart disease clinical trial?
Each congenital heart disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.
How do I find a congenital heart disease trial near me?
Use the location controls above. We'll show recruiting congenital heart disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.
How many congenital heart disease trials are recruiting right now?
We're currently tracking roughly 42 recruiting congenital heart disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.
Looking for a specific location? Browse trials by city and state.