Paid Clinical Trials in Burlington, MA
As of June 2026, 93 paid clinical trials are recruiting in Burlington, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Burlington offers studies at sites including Lahey Hospital and Medical Center for conditions such as Breast Cancer, ARDS, Acute Respiratory Distress Syndrome, ARDS (Acute Respiratory Distress Syndrome). Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Burlington
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·Clear filters·↓ Download CSVAbout research studies in Burlington
Burlington has approximately 93 recruiting research studies across a wide range of therapeutic areas. Massachusetts is a global epicenter of biomedical research, anchored by Harvard-affiliated hospitals (MGH, Brigham and Women's, Dana-Farber), Boston Children's Hospital, and the Kendall Square biotech corridor in Cambridge.
Top Research Study Locations in Burlington
Researchers run research studies in Burlington, MA at 24 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Lahey Hospital and Medical Center | Breast Cancer, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 46 |
| Lahey Hospital & Medical Center | Atrial Fibrillation, Carcinoma, Non-Small-Cell Lung, Tricuspid Valve Disease | 17 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Lahey Clinic | ALS, Breast Cancer, HER2-positive Breast Cancer | 2 |
| Lahey Clinic, Inc | Acute Respiratory Failure, Diagnosis, Prostate Cancer | 2 |
| Lahey Clinic, Inc. | Bladder Neoplasms, Cancer, Cardiac Arrythmias | 2 |
| Skylight Health Research | COVID-19, Influenza | 2 |
| Beth Israel Lahey Health | Breast Cancer | 1 |
| Beth Israel Lahey Health - Lahey Hospital & Medical Center (LHMC), Lahey Clinic Medical Center | Extensive-stage Small-cell Lung Cancer | 1 |
| Clinical Study Site | Chronic Inflammatory Demyelinating Polyneuropathy | 1 |
| Direct Biologics Investigational Site | ARDS, Acute Respiratory Distress Syndrome | 1 |
| Imbria Investigational Site | Non-obstructive Hypertrophic Cardiomyopathy | 1 |
| Invivyd Investigative Site | COVID-19 | 1 |
| Lahey Clinic Burlington | Lumbar Spinal Stenosis | 1 |
| Lahey Clinic Inc. | Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism | 1 |
| Lahey Clinic Medical Center | Liver Transplant | 1 |
| Lahey Hospital | Non-Small Cell Lung Cancer | 1 |
| Lahey Hospital & Medical Centeer | Atrial Fibrillation, Stroke | 1 |
| Local Institution - Unk039 | Advanced NSCLC, Metastatic Lung Cancer | 1 |
| Site 0307 - Lahey Hospital and Medical Center | High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer | 1 |
| Skylight Health Research - Burlington | Osteoarthritis, Overweight or Obesity | 1 |
| Skylight Health Research Burlington | Knee Osteoarthritis, Synovitis of Knee | 1 |
| Skylight Health Research, - Burlington | COVID-19 Infection | 1 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Relapsing Multiple Sclerosis | 1 |
Active & Upcoming Studies in Burlington (2026)
Recruiting trials in Burlington grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (45 active studies)
- SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers · Beth Israel Deaconess Medical Center
- Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 · Phase 3 · AstraZeneca
Cardiovascular (7 active studies)
- Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System · P+F Products + Features USA Inc.
- A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B) · Phase 1, Phase 2 · Novartis Pharmaceuticals
Neurology & pain (5 active studies)
- Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis. · Phase 3 · Novartis Pharmaceuticals
- A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS) · TG Therapeutics, Inc.
Vaccines (4 active studies)
- Study of VYD2311 for the Prevention of COVID-19 · Phase 3 · Invivyd, Inc.
- Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults · Phase 2 · CastleVax Inc.
Diabetes & metabolic (3 active studies)
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Common conditions studied in Burlington
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- ARDS (5 active studies). Recruiting ARDS studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Respiratory Distress Syndrome (5 active studies). Recruiting Acute Respiratory Distress Syndrome studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- ARDS (Acute Respiratory Distress Syndrome) (4 active studies). Recruiting ARDS (Acute Respiratory Distress Syndrome) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Respiratory Distress Syndrome (ARDS) (4 active studies). Recruiting Acute Respiratory Distress Syndrome (ARDS) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Atrial Fibrillation (4 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
Leading research sponsors in Burlington
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- NRG Oncology
- PPD Development, LP
- Alliance for Clinical Trials in Oncology
Local regulations and guidelines
Clinical trials in Massachusetts are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Massachusetts trials follow additional state privacy requirements enforced under 201 CMR 17.00 and oversight from the Massachusetts Department of Public Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Burlington. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Burlington
Hipa.ai aggregates every recruiting study in Burlington from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Burlington?
There are approximately 93 recruiting clinical trials in Burlington, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Burlington pay participants?
Most recruiting trials in Burlington compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Burlington?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Burlington?
The most common conditions under active study in Burlington include Breast Cancer (8), ARDS (5), Acute Respiratory Distress Syndrome (5), ARDS (Acute Respiratory Distress Syndrome) (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Burlington?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Burlington on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Burlington?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Burlington?
Recruiting research sites in Burlington include Lahey Hospital and Medical Center, Lahey Hospital & Medical Center, 89bio Clinical Study Site, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Burlington right now?
The largest active categories in Burlington are Cancer & tumors (45), Cardiovascular (7), Neurology & pain (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.