Mental health Clinical Trials in Cincinnati, OH
As of July 2026, 22 paid clinical trials are recruiting for Mental health in Cincinnati, Ohio. Mental health research covers new pharmacotherapies, psychotherapies, and digital interventions for depression, anxiety, PTSD, bipolar disorder, and sleep — including treatments for treatment-resistant cases. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Cincinnati
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Impact of Short and Mistimed Sleep on Adolescents With ADHD: The Adolescent Attention and Circadian Timing Study
24 clinical trials for Mental health
·Clear filters·↓ Download CSVStudy to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
E-Mindfulness Approaches for Living After Breast Cancer
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation
Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement
ADHD PreSMA Response Inhibition Therapy
AWARE: Management of ADHD in Autism Spectrum Disorder
SMART Therapist Training: A Hybrid Factorial-SMART Design
Suicide Treatment Alternatives for Teens
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.
Evaluating Treatment of ADHD in Children with Down Syndrome
Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)
Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)
Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
Study of ALTO-300 in MDD
Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
About research studies in Cincinnati
Cincinnati has approximately 1,083 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Top Research Study Locations in Cincinnati
Researchers run research studies in Cincinnati, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cincinnati Children's Hospital Medical Center | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Neuroblastoma | 281 |
| University of Cincinnati | Stroke, Chronic Lymphocytic Leukemia, Multiple Myeloma | 102 |
| University of Cincinnati Medical Center | Advanced Solid Tumor, Interstitial Lung Disease, Stroke | 66 |
| Cincinnati Children's Hospital | Amblyopia, Musculoskeletal Pain, Acute Kidney Injury | 45 |
| University of Cincinnati Cancer Center-UC Medical Center | Metastatic Malignant Neoplasm in the Brain, Metastatic Renal Cell Carcinoma, Stage III Hypopharyngeal Carcinoma AJCC v8 | 43 |
| The Christ Hospital | Tricuspid Regurgitation, Advanced Solid Tumor, Aortic Stenosis | 36 |
| Good Samaritan Hospital - Cincinnati | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Malignant Solid Neoplasm | 35 |
| Bethesda North Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Malignant Solid Neoplasm | 34 |
| TriHealth Cancer Institute-Anderson | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Malignant Solid Neoplasm | 25 |
| TriHealth Cancer Institute-Westside | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Malignant Solid Neoplasm | 25 |
| Oncology Hematology Care | Multiple Myeloma, Breast Cancer, Acute Myeloid Leukemia (AML) | 15 |
| CTI Clinical Research Center | Obesity, Overweight, Obstructive Sleep Apnea | 14 |
| Cincinnati Eye Institute | Cone Rod Dystrophy, Juvenile Macular Degeneration, Stargardt Disease | 13 |
| Oncology Hematology Care Inc-Kenwood | Acral Lentiginous Melanoma, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 11 |
| Good Samaritan Hospital | Atrial Fibrillation, Chronic Subdural Hematoma, Deep Vein Thrombosis | 8 |
| University of Cincinnati Cancer Center | Colorectal Cancer, Anaplastic Lymphoma Kinase-positive, Cutaneous Melanoma | 8 |
| University of Cincinnati College of Medicine | Acetabular Fracture, Adolescents, Atrial Fibrillation | 8 |
| Cincinnati Childrens Hospital Medical Center | Adrenal Insufficiency, Alopecia, Areata Alopecia | 7 |
| GSK Investigational Site | HIV Infections, Asthma, Chickenpox | 7 |
| Oncology Hematology Care Clinical Trials, LLC | Carcinoma, Non-Small-Cell Lung, Chronic Graft-Versus-Host Disease (cGVHD), Esophageal Adenocarcinoma | 5 |
| Alkermes Investigational Site | Narcolepsy Type 1, Narcolepsy Type 2, Bipolar I Disorder | 5 |
| Children's Hospital Medical Center | Biliary Atresia, Duchenne Muscular Dystrophy, Essential Fatty Acid Deficiency | 5 |
| Christ Hospital | Acute or Chronic Coronary Artery Disease, Cardiovascular Diseases, Coronary Artery Disease | 5 |
| Cincinnati Children's Medical Center | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 5 |
| The Christ Hospital Cancer Center | Advanced Adenocarcinoma, Breast Cancer, Extensive-stage Small-cell Lung Cancer | 5 |
Active & Upcoming Studies in Cincinnati (2026)
Recruiting trials in Cincinnati grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (285 active studies)
- A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer · Children's Hospital Medical Center, Cincinnati
- Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma · Phase 3 · Hoffmann-La Roche
Cardiovascular (89 active studies)
- Adapting Enhanced Supports to Improve Patient Adherence to Secondary Antibiotic Prophylaxis for Rheumatic Heart Disease · Children's Hospital Medical Center, Cincinnati
- A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis · Phase 2 · Beijing Inno Medicine Co., Ltd.
Neurology & pain (75 active studies)
- The BRIDGE Pain Study · Children's Hospital Medical Center, Cincinnati
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Pediatric (36 active studies)
- Adapting Enhanced Supports to Improve Patient Adherence to Secondary Antibiotic Prophylaxis for Rheumatic Heart Disease · Children's Hospital Medical Center, Cincinnati
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Diabetes & metabolic (30 active studies)
- GLP-1 RA for Stage 1 Type 1 Diabetes · Phase 2 · Children's Hospital Medical Center, Cincinnati
- A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin · Phase 3 · AstraZeneca
Mental health & behavior (23 active studies)
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
Eye & vision (13 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
HIV / STI (8 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Health-E You Efficacy Trial for Male Adolescents · Johns Hopkins University
Vaccines (7 active studies)
Common conditions studied in Cincinnati
- Heart Failure (18 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Obesity (13 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Breast Cancer (12 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Multiple Myeloma (11 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cystic Fibrosis (10 active studies). Recruiting Cystic Fibrosis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Migraine (10 active studies). Migraine trials evaluate CGRP antagonists, gepants, and new acute and preventive therapies for chronic and episodic migraine.
Leading research sponsors in Cincinnati
- Children's Hospital Medical Center, Cincinnati
- University of Cincinnati
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Cincinnati. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Cincinnati
Hipa.ai aggregates every recruiting study in Cincinnati from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Cincinnati?
There are approximately 1,083 recruiting clinical trials in Cincinnati, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cincinnati pay participants?
Most recruiting trials in Cincinnati compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cincinnati?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cincinnati?
The most common conditions under active study in Cincinnati include Heart Failure (18), Obesity (13), Breast Cancer (12), Multiple Myeloma (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cincinnati?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cincinnati on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cincinnati?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cincinnati?
Recruiting research sites in Cincinnati include Cincinnati Children's Hospital Medical Center, University of Cincinnati, University of Cincinnati Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cincinnati right now?
The largest active categories in Cincinnati are Cancer & tumors (285), Cardiovascular (89), Neurology & pain (75). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.