Urology Clinical Trials in Cleveland, OH
As of September 2026, 37 paid clinical trials are recruiting for Urology in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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37 clinical trials for Urology
·Clear filters·This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
Sacral Neuromodulation for Male Overactive Bladder (MOAB)
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)
Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
Study With [225Ac]Ac-FL-020 in mCRPC Participants
Pelvic Health Electrically Evoked Recording (PEER) 2 Study
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
The Vanguard Study: Testing a New Way to Screen for Cancer
Investigation of Impact of AI on Prostate Cancer Workflow
MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)
Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer
Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound
International Registry for Men With Advanced Prostate Cancer (IRONMAN)
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr
Cleveland African American Prostate Cancer Project
Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer
Feasibility of Triggered Sacral Neuromodulation for Neurogenic Bladder
Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma
Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
Self-Start Triage Model for Post-Botox® Lower Urinary Tract Symptoms
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
Top Research Study Locations in Cleveland
Researchers run research studies in Cleveland, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cleveland Clinic | Heart Failure, Cardiovascular Diseases, Colorectal Cancer | 362 |
| University Hospitals Cleveland Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 156 |
| Cleveland Clinic Foundation | Heart Failure, COPD, Stroke | 143 |
| Case Western Reserve University | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Dementia | 76 |
| MetroHealth Medical Center | Spinal Cord Injuries, Spinal Cord Injury Cervical, Stage IVB Prostate Cancer AJCC v8 | 35 |
| The Cleveland Clinic Foundation | Heart Diseases, Aortic Valve Insufficiency, Cardiovascular Diseases | 28 |
| Rainbow Babies and Childrens Hospital | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Down Syndrome | 26 |
| Louis Stokes VA Medical Center, Cleveland, OH | Spinal Cord Injury, Diabetes, Parkinson's Disease | 24 |
| Cleveland Clinic Main Campus | Breast Cancer, Abdominal Wall Hernia, Blood Pressure | 18 |
| The Cleveland Clinic | Depression / Major Depressive Disorder, Hopelessness, Suicidal Ideation | 17 |
| Cleveland Clinic Cancer Center/Fairview Hospital | Ovarian Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 13 |
| University Hospitals | B Cell Lymphoma, Bladder Pain Syndrome, CLL | 12 |
| UH Cleveland Medical Center | Breast Cancer, Acute Decompensated Heart Failure, Atrial Fibrillation | 11 |
| University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center | Acute Lymphocytic Leukemia, Bile Duct Cancer, Brain Metastases | 11 |
| University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center | Pancreatic Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 10 |
| Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center | Acute Myeloid Leukemia, Cyst of Pancreas, Cytokine Release Syndrome | 10 |
| Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute | Amyloid Light-chain Amyloidosis, B-cell Non Hodgkin Lymphoma, Basal Cell Carcinoma | 8 |
| Cleveland Clinic Taussig Cancer Center | Glioma, Advanced Solid Tumor, Barrett Esophagus | 8 |
| The MetroHealth System | AV Block, COVID-19, Coronavirus Infections | 8 |
| University Hospitals Cleveland | 1st Line NSCLC, Abdominal Aortic Aneurysm, Advanced Solid Tumor | 8 |
| University Hospitals of Cleveland | Advanced Solid Tumors, Aortic Aneurysm, Aortic Dissection | 8 |
| Cleveland Clinic - Cleveland | Antibody-Mediated Rejection (AMR), Myelodysplastic Syndromes, SBS Associated With Intestinal Failure (SBS-IF) | 8 |
| Cleveland Clinic Fairview Hospital | HPV Infection, Pre-Cancerous Dysplasia, Bleeding | 7 |
| Louis Stokes Cleveland VA Medical Center | Multiple Sclerosis, Stroke, Adenocarcinoma of the Colon | 7 |
| MetroHealth | Acute Kidney Injury, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 7 |
Active & Upcoming Studies in Cleveland (2026)
Recruiting trials in Cleveland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (376 active studies)
- TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE) · Case Comprehensive Cancer Center
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
Cardiovascular (104 active studies)
- Metabolic Surgery for Atrial Fibrillation Elimination · Phase 4 · Ali Aminian
- Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation · Oslo University Hospital
Neurology & pain (87 active studies)
- REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis · Case Western Reserve University
- A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MS · Phase 2 · Moein Amin
Diabetes & metabolic (36 active studies)
- Whole Gut Motility Abnormalities Following GLP-1 Receptor Agonist (GLP-1RA) Initiation · The Cleveland Clinic
- PNS to Improve Vascular Function and Limb Health in Veterans · VA Office of Research and Development
Eye & vision (17 active studies)
- Study of Serine Supplementation to Protect Vision in MacTel · Phase 3 · The Lowy Medical Research Institute Limited
- Noninvasive Imaging Biomarkers of Treatable Macrovascular Disease in Age-related Macular Degeneration. · Scott Raymond
Mental health & behavior (16 active studies)
- Neural Correlates of Suicidal Behavior in Youth · The Cleveland Clinic
- Reduction of Anxiety Through Dual Treatment: Digital CBT & NBHWC Coaching · Toivoa Inc
Pediatric (16 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- Humidity Asthma Interventions for Low Socioeconomic Status Children · Case Western Reserve University
HIV / STI (6 active studies)
- Dasatinib for HIV-1 Reservoir Reduction · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Menopausal HT for Women Living With HIV (HoT) · Phase 4 · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Vaccines (5 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
Common conditions studied in Cleveland
- Heart Failure (29 active studies)
- Advanced Solid Tumor (19 active studies)
- Breast Cancer (19 active studies)
- Cardiovascular Diseases (17 active studies)
- Prostate Cancer (16 active studies)
- Coronary Artery Disease (15 active studies)
Leading research sponsors in Cleveland
- The Cleveland Clinic
- Case Comprehensive Cancer Center
- University Hospitals Cleveland Medical Center
- National Cancer Institute (NCI)
- Case Western Reserve University
Frequently asked questions
How many paid clinical trials are currently recruiting in Cleveland?
There are approximately 1,266 recruiting clinical trials in Cleveland, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cleveland pay participants?
Most recruiting trials in Cleveland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cleveland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cleveland?
The most common conditions under active study in Cleveland include Heart Failure (29), Advanced Solid Tumor (19), Breast Cancer (19), Cardiovascular Diseases (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cleveland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cleveland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cleveland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cleveland?
Recruiting research sites in Cleveland include Cleveland Clinic, University Hospitals Cleveland Medical Center, Cleveland Clinic Foundation, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cleveland right now?
The largest active categories in Cleveland are Cancer & tumors (376), Cardiovascular (104), Neurology & pain (87). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.