Neurology Clinical Trials in Columbus, OH
As of September 2026, 45 paid clinical trials are recruiting for Neurology in Columbus, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Columbus
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
46 clinical trials for Neurology
·Clear filters·A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Strategy for Improving Stroke Treatment Response
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod
CoMind Early Feasibility Study
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis
A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
PREVENT ALL ALS Study
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Responding With Evidence and Access for Childhood Headaches
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
Implementation of TBI-RECOVER in Substance Use Treatment
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
A Study of Ranolazine in ALS
Cognitive Status After Removal of Skull Base Meningioma
Diet and Exercise Solutions to Postprandial Hypotension
Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study
Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
StrokeNet Thrombectomy Endovascular Platform
Cognitive Assessment Tools for Huntington's Disease.
Augmented Renal Clearance in Neurocritical Care
Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease
Top Research Study Locations in Columbus
Researchers run research studies in Columbus, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Ohio State University Comprehensive Cancer Center | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Chronic Lymphocytic Leukemia | 243 |
| Nationwide Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Surgery | 215 |
| The Ohio State University | Healthy, Heart Failure, Prostate Cancer | 143 |
| Ohio State University | Colorectal Cancer, Coronary Artery Disease, Non-Small Cell Lung Cancer | 127 |
| The Ohio State University Wexner Medical Center | Follicular Lymphoma, Endometrial Cancer, Hypertension | 77 |
| Riverside Methodist Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 29 |
| Ohio State University Wexner Medical Center | Anxiety, Chronic Nausea, Endometrial Cancer | 28 |
| Doctors Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 24 |
| Grant Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 24 |
| The Ohio State University Comprehensive Cancer Center | Colorectal Cancer, Cancer, CRC | 24 |
| The Mark H Zangmeister Center | Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 20 |
| Mount Carmel East Hospital | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Hematopoietic and Lymphoid Cell Neoplasm | 19 |
| Columbus Oncology and Hematology Associates Inc | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 18 |
| Ohio State University Medical Center | AL Amyloidosis, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 16 |
| OSU Wexner Medical Center | Intracerebral Hemorrhage, Ischemic Stroke, Acute Hypoxic Respiratory Failure | 15 |
| Mount Carmel Health Center West | Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Acral Lentiginous Melanoma | 14 |
| OhioHealth Research Institute | Atrial Fibrillation, Acute Ischemic Stroke, Acute Myeloid Leukaemia (AML) | 13 |
| The Ohio State University Medical Center | AADC Deficiency, Abdominal Aortic Aneurysm, Bone Marrow Transplant (BMT) | 11 |
| The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine | Pregnancy, High Risk, Preeclampsia, Gestational Hypertension | 10 |
| Clinical Trial Site | AQP4+ NMOSD, ATTR Amyloidosis, Breast Cancer | 9 |
| GSK Investigational Site | Gastrointestinal Neoplasms, HIV Infections, Hypereosinophilic Syndrome | 9 |
| Ohio Health Research Institute | Aortic Dissection, Aortic Valve Disease, Aortic Valve Stenosis | 9 |
| Nationwide Children's Hosptial | Primary Immune Deficiency Disorder, Adenovirus, Congenital Cytomegaloviral (CMV) Disease | 7 |
| OhioHealth Riverside Methodist Hospital | Aortic Stenosis, Carcinoma, Non-Small-Cell Lung, Coronary Artery Disease | 7 |
| Nationwide Children's | Acute Kidney Injury, Becker Muscular Dystrophy, Cardiomyopathy | 6 |
Active & Upcoming Studies in Columbus (2026)
Recruiting trials in Columbus grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (494 active studies)
- Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma · Phase 1 · Northwestern University
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
Cardiovascular (81 active studies)
- Health Coaching for Patients With Cardiovascular Disease · Ohio State University
- Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension · Ohio State University
Neurology & pain (71 active studies)
- VR-PAT and fNIRS to Identify CNS Biomarkers of Pain · Nationwide Children's Hospital
- Prescriptive Infusion Algorithm (PIA) · Phase 2 · AskBio Inc
Mental health & behavior (51 active studies)
- Clinical Evaluation of an Alarm Activated Detection System to Enable Early Intervention of Emerging Respiratory Decline With the Linshom Medical Continuous Predictive Respiratory Sensor (CPRS) · Linshom Medical, Inc.
- The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke · Ohio State University Comprehensive Cancer Center
Diabetes & metabolic (42 active studies)
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
- Atomoxetine in Melanocortin Obesity Syndrome · Phase 2 · Icahn School of Medicine at Mount Sinai
Pediatric (35 active studies)
- VR-PAT and fNIRS to Identify CNS Biomarkers of Pain · Nationwide Children's Hospital
- Bilevel Positive Airway Pressure (BPAP) for Severe Asthma · Columbia University
HIV / STI (12 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
Vaccines (7 active studies)
Eye & vision (5 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK · Phase 3 · Kodiak Sciences Inc
Common conditions studied in Columbus
- Acute Myeloid Leukemia (20 active studies)
- Breast Cancer (19 active studies)
- Chronic Lymphocytic Leukemia (18 active studies)
- Ovarian Cancer (17 active studies)
- Endometrial Cancer (16 active studies)
- Malignant Solid Neoplasm (15 active studies)
Leading research sponsors in Columbus
- Ohio State University
- Ohio State University Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Nationwide Children's Hospital
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbus?
There are approximately 1,378 recruiting clinical trials in Columbus, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbus pay participants?
Most recruiting trials in Columbus compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbus?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbus?
The most common conditions under active study in Columbus include Acute Myeloid Leukemia (20), Breast Cancer (19), Chronic Lymphocytic Leukemia (18), Ovarian Cancer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbus?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbus on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbus?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbus?
Recruiting research sites in Columbus include Ohio State University Comprehensive Cancer Center, Nationwide Children's Hospital, The Ohio State University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbus right now?
The largest active categories in Columbus are Cancer & tumors (494), Cardiovascular (81), Neurology & pain (71). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.