Solid tumor Clinical Trials in Dallas, TX
As of August 2026, 59 paid clinical trials are recruiting for Solid tumor in Dallas, Texas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Dallas
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
60 clinical trials for Solid tumor
·Clear filters·A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies
A Study of ASP1002 in Adults for Treatment of Solid Tumors
A Study of ZL-1310 in Participants With Selected Solid Tumors
BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
A Study of PYX-201 in Advanced Solid Tumors
A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors
JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
Study of SGR-3515 In Participants With Advanced Solid Tumors.
Study of AVZO-021 in Patients With Advanced Solid Tumors
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors
SW-682 in Advanced Solid Tumors
A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours
Study of STP938 (Dencatistat) in Advanced Solid Tumours
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
A Study to Evaluate the Efficacy and Safety of TL118 in Solid Tumors Patients
A Study of VET3-TGI in Patients With Solid Tumors
Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.
Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors
A Study of KK2269 in Adult Participants With Solid Tumors
A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors
ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)
Top Research Study Locations in Dallas
Researchers run research studies in Dallas, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Texas Southwestern Medical Center | Heart Failure, Prostate Cancer, Advanced Breast Cancer | 204 |
| UT Southwestern Medical Center | Hypertension, Obesity, Renal Cell Carcinoma | 176 |
| UT Southwestern/Simmons Cancer Center-Dallas | Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8, Acute Myeloid Leukemia | 74 |
| University of Texas Southwestern | Cystic Fibrosis, Lymphoma, Non-Hodgkin, Multiple Myeloma | 62 |
| Baylor University Medical Center | Heart Failure, Interstitial Lung Disease, AML | 45 |
| The University of Texas Southwestern Medical Center | Anxiety, Breast Cancer, Depression Disorders | 28 |
| Parkland Memorial Hospital | Stage IIIB Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8, Endometrial Clear Cell Adenocarcinoma | 27 |
| Medical City Dallas Hospital | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 24 |
| UT Southwestern Simmons Cancer Center - RedBird | Stage IVB Prostate Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Metastatic Renal Cell Carcinoma | 23 |
| Retina Foundation of the Southwest | Stargardt Disease, Age-Related Macular Degeneration, Amblyopia | 21 |
| Mary Crowley Cancer Research | Advanced Solid Tumor, Endometrial Cancer, Solid Tumor | 20 |
| UT Southwestern | AQP4+ NMOSD, Acute Kidney Injury, Advanced Endometrial Carcinoma | 20 |
| Baylor Scott & White Research Institute | Emphysema, Acute Respiratory Failure, Astrocytoma, Grade III | 19 |
| VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX | Cirrhosis, Heart Failure, Acute Kidney Injury | 19 |
| Zenos Clinical Research | Diabetic Peripheral Neuropathic Pain, Gout, Type 2 Diabetes | 17 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Chickenpox, HIV Infections | 15 |
| Methodist Dallas Medical Center | Achalasia, Acute Kidney Injury (AKI), BK Viremia | 14 |
| Texas Oncology - DFW | Breast Cancer, Endometrial Cancer, Pancreatic Cancer | 12 |
| Children's Medical Center Dallas | Niemann-Pick Type C Disease, Acute Kidney Injury, Acute Kidney Injury Due to Sepsis | 12 |
| Texas Oncology | Advanced Melanoma, Advanced Non-Small-Cell Lung Cancer, Advanced/Metastatic Solid Tumors | 12 |
| FutureSearch Trials of Dallas | Obesity, Overweight, Acute Treatment of Migraine | 10 |
| Methodist Dallas Medical Center- Clinical Research Institute | Trauma, Gastro-Intestinal Disorder, Chronic Pancreatitis | 10 |
| University of Texas Southwestern Medical Center at Dallas | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 9 |
| Children's Medical Center | Neuroblastoma, Ewing Sarcoma, Osteosarcoma | 8 |
| Southwest Family Medicine Associates | Heart Failure, Atherosclerosis, Atherosclerotic Cardiovascular Disease (ASCVD) | 8 |
Active & Upcoming Studies in Dallas (2026)
Recruiting trials in Dallas grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (429 active studies)
- Molecular Breast Imaging (MBI)-Guided Biopsy · Smart Breast Corp.
- Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization · University of Colorado, Denver
Cardiovascular (125 active studies)
- Value of Potassium Magnesium Citrate in Preventing and Treating Hypertension in African Americans · Phase 2 · University of Texas Southwestern Medical Center
- Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure · Phase 3 · University of Texas Southwestern Medical Center
Neurology & pain (78 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Cholinergic Enhancement of Theta · EARLY_Phase 1 · University of Texas Southwestern Medical Center
Diabetes & metabolic (71 active studies)
Mental health & behavior (41 active studies)
- Optimizing CBSST With Executive Function Training for Schizophrenia (R33) · University of California, San Diego
- tDCS for Late-Life Depression · Andre Russowsky Brunoni
Eye & vision (31 active studies)
Pediatric (24 active studies)
- Comparing Surfactant Administration Through Supraglottic Airway and Thin Catheter for Preterm Infants · University of Texas Southwestern Medical Center
- Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression · University of Texas Southwestern Medical Center
HIV / STI (20 active studies)
Vaccines (6 active studies)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
Common conditions studied in Dallas
- Heart Failure (32 active studies)
- Breast Cancer (31 active studies)
- Obesity (23 active studies)
- Prostate Cancer (20 active studies)
- Advanced Solid Tumor (19 active studies)
- Endometrial Cancer (16 active studies)
Leading research sponsors in Dallas
- University of Texas Southwestern Medical Center
- Baylor Research Institute
- Eli Lilly and Company
- AstraZeneca
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Dallas?
There are approximately 1,553 recruiting clinical trials in Dallas, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Dallas pay participants?
Most recruiting trials in Dallas compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Dallas?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Dallas?
The most common conditions under active study in Dallas include Heart Failure (32), Breast Cancer (31), Obesity (23), Prostate Cancer (20), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Dallas?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Dallas on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Dallas?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Dallas?
Recruiting research sites in Dallas include University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Dallas right now?
The largest active categories in Dallas are Cancer & tumors (429), Cardiovascular (125), Neurology & pain (78). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.