Oncology Clinical Trials in Dallas, TX
As of August 2026, 304 paid clinical trials are recruiting for Oncology in Dallas, Texas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Dallas
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
305 clinical trials for Oncology
·Clear filters·A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Top Research Study Locations in Dallas
Researchers run research studies in Dallas, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Texas Southwestern Medical Center | Heart Failure, Prostate Cancer, Advanced Breast Cancer | 204 |
| UT Southwestern Medical Center | Hypertension, Obesity, Renal Cell Carcinoma | 176 |
| UT Southwestern/Simmons Cancer Center-Dallas | Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8, Acute Myeloid Leukemia | 74 |
| University of Texas Southwestern | Cystic Fibrosis, Lymphoma, Non-Hodgkin, Multiple Myeloma | 62 |
| Baylor University Medical Center | Heart Failure, Interstitial Lung Disease, AML | 45 |
| The University of Texas Southwestern Medical Center | Anxiety, Breast Cancer, Depression Disorders | 28 |
| Parkland Memorial Hospital | Stage IIIB Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8, Endometrial Clear Cell Adenocarcinoma | 27 |
| Medical City Dallas Hospital | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 24 |
| UT Southwestern Simmons Cancer Center - RedBird | Stage IVB Prostate Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Metastatic Renal Cell Carcinoma | 23 |
| Retina Foundation of the Southwest | Stargardt Disease, Age-Related Macular Degeneration, Amblyopia | 21 |
| Mary Crowley Cancer Research | Advanced Solid Tumor, Endometrial Cancer, Solid Tumor | 20 |
| UT Southwestern | AQP4+ NMOSD, Acute Kidney Injury, Advanced Endometrial Carcinoma | 20 |
| Baylor Scott & White Research Institute | Emphysema, Acute Respiratory Failure, Astrocytoma, Grade III | 19 |
| VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX | Cirrhosis, Heart Failure, Acute Kidney Injury | 19 |
| Zenos Clinical Research | Diabetic Peripheral Neuropathic Pain, Gout, Type 2 Diabetes | 17 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Chickenpox, HIV Infections | 15 |
| Methodist Dallas Medical Center | Achalasia, Acute Kidney Injury (AKI), BK Viremia | 14 |
| Texas Oncology - DFW | Breast Cancer, Endometrial Cancer, Pancreatic Cancer | 12 |
| Children's Medical Center Dallas | Niemann-Pick Type C Disease, Acute Kidney Injury, Acute Kidney Injury Due to Sepsis | 12 |
| Texas Oncology | Advanced Melanoma, Advanced Non-Small-Cell Lung Cancer, Advanced/Metastatic Solid Tumors | 12 |
| FutureSearch Trials of Dallas | Obesity, Overweight, Acute Treatment of Migraine | 10 |
| Methodist Dallas Medical Center- Clinical Research Institute | Trauma, Gastro-Intestinal Disorder, Chronic Pancreatitis | 10 |
| University of Texas Southwestern Medical Center at Dallas | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 9 |
| Children's Medical Center | Neuroblastoma, Ewing Sarcoma, Osteosarcoma | 8 |
| Southwest Family Medicine Associates | Heart Failure, Atherosclerosis, Atherosclerotic Cardiovascular Disease (ASCVD) | 8 |
Active & Upcoming Studies in Dallas (2026)
Recruiting trials in Dallas grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (429 active studies)
- Molecular Breast Imaging (MBI)-Guided Biopsy · Smart Breast Corp.
- Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization · University of Colorado, Denver
Cardiovascular (125 active studies)
- Value of Potassium Magnesium Citrate in Preventing and Treating Hypertension in African Americans · Phase 2 · University of Texas Southwestern Medical Center
- Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure · Phase 3 · University of Texas Southwestern Medical Center
Neurology & pain (78 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Cholinergic Enhancement of Theta · EARLY_Phase 1 · University of Texas Southwestern Medical Center
Diabetes & metabolic (71 active studies)
Mental health & behavior (41 active studies)
- Optimizing CBSST With Executive Function Training for Schizophrenia (R33) · University of California, San Diego
- tDCS for Late-Life Depression · Andre Russowsky Brunoni
Eye & vision (31 active studies)
Pediatric (24 active studies)
- Comparing Surfactant Administration Through Supraglottic Airway and Thin Catheter for Preterm Infants · University of Texas Southwestern Medical Center
- Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression · University of Texas Southwestern Medical Center
HIV / STI (20 active studies)
Vaccines (6 active studies)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
Common conditions studied in Dallas
- Heart Failure (32 active studies)
- Breast Cancer (31 active studies)
- Obesity (23 active studies)
- Prostate Cancer (20 active studies)
- Advanced Solid Tumor (19 active studies)
- Endometrial Cancer (16 active studies)
Leading research sponsors in Dallas
- University of Texas Southwestern Medical Center
- Baylor Research Institute
- Eli Lilly and Company
- AstraZeneca
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Dallas?
There are approximately 1,553 recruiting clinical trials in Dallas, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Dallas pay participants?
Most recruiting trials in Dallas compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Dallas?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Dallas?
The most common conditions under active study in Dallas include Heart Failure (32), Breast Cancer (31), Obesity (23), Prostate Cancer (20), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Dallas?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Dallas on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Dallas?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Dallas?
Recruiting research sites in Dallas include University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Dallas right now?
The largest active categories in Dallas are Cancer & tumors (429), Cardiovascular (125), Neurology & pain (78). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.