Paid Clinical Trials in Fresno, CA

As of June 2026, 116 paid clinical trials are recruiting in Fresno, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Fresno offers studies at sites including Kaiser Permanente-Fresno for conditions such as ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome, Acute Respiratory Distress Syndrome (ARDS). Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Trials by specialty in Fresno

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About research studies in Fresno

Fresno has approximately 116 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.

Top Research Study Locations in Fresno

Researchers run research studies in Fresno, CA at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
Kaiser Permanente-FresnoStage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Breast Cancer33
Kaiser Permanente Fresno Orchard PlazaStage IIIB Lung Cancer AJCC v8, Breast Cancer, Stage IV Lung Cancer AJCC v832
Fresno Cancer CenterBreast Cancer, Ovarian Carcinoma, Stage IVA Prostate Cancer AJCC v814
Community Regional Medical CenterARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome9
Neuro-Pain Medical CenterAlzheimer's Disease Psychosis, Chronic Migraine, Diabetic Peripheral Neuropathic Pain5
Limb Preservation Platform, Inc.Diabetic Foot Ulcer, Diabetic Foot Ulcer (DFU), Venous Leg Ulcer3
University of California San FranciscoLiver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH), Multiple Myeloma3
Neuro Pain Research CenterMigraine, Chronic Migraine3
89bio Clinical Study SiteMetabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis2
Community Regional Trauma and Burn CenterDental Pain, Traumatic Lacerations2
Fresno Clinical Research CenterMetabolic Dysfunction-Associated Steatohepatitis, Metabolic Dysfunction-Associated Steatotic Liver Disease2
Neuro-Pain Research CenterAcute Treatment of Migraine, Pediatric Migraine2
The Medical Research Group, Inc.Atherosclerotic Cardiovascular Disease in Patients With ESKD, IgA Nephropathy2
University of California San Francisco-FresnoClassic Hodgkin Lymphoma, Community-acquired Pneumonia, Hodgkin Lymphoma, Adult2
Urology Associates of Central CaliforniaBenign Prostatic Hyperplasia (BPH), Intermediate Risk Non-Muscle Invasive Bladder Cancer2
UCSF FresnoHypothermia Due to Cold Environment, Trauma Patients, B Cell Lymphoma2
Advanced Pain SolutionsLumbar Spinal Stenosis1
Altimmune Clinical Study SiteAlcohol Liver Disease1
Behr Laser & Skin Care CenterPost Procedural Erythema1
California Cancer Associates for Research & ExcellenceHematologic Malignancies, Solid Tumors1
California Cancer Associates for Research & Excellence, Inc.Colorectal Cancer1
California Cancer Associates for Research and ExcellenceAdvanced Solid Tumor, Metastatic Solid Tumor1
ClinRé 001-022 (Premier Cancer Care and Infusion Center)Non-small Cell Lung Cancer1
Clincial ResearchNon-healing Wound, Venous Insufficiency of Leg, Venous Leg Ulcer1
Clinical Res of Central CaDiabetes Mellitus, Type 11
Clinical Trial SiteGeneralized Myasthenia Gravis1
Community Foundation Medical GroupArthroplasty Complications, Infection, Knee Disease1
Community Health Partners NeuroscienceDegenerative Disc Disease, Spinal Stenosis1
Community Regional Medical Center of FresnoAtrial Fibrillation, Intracerebral Hemorrhage1
Comprehensive Pain Management CenterLumbar Spinal Stenosis1
Costanzo OrthodonticsMalocclusion1
Eye Medical Center of FresnoAge-related Macular Degeneration (AMD), Geographic Atrophy (GA)1
Fresno Community Hospital and Medical CenterARDS, Pneumonia, Sepsis1
Fresno Surgical HospitalLumbar Spinal Stenosis1
Fresno VA Medical CenterCardiovascular Diseases, Cognitive Impairment, Mild, Dementia1
Herndon Surgery CenterLumbar Spinal Stenosis1
Kaiser PermanenteLumbar Spinal Stenosis1
Kaiser Permanente Fresno Medical CenterLumbar Spinal Stenosis1
Ky Advanced Surgical Center, Inc.Lumbar Spinal Stenosis1
Limb Preservaion Platform, Inc.Diabetic Foot Ulcer (DFU), Lower Extremity1
Limb Preservation Platform IncChronic Foot Ulcers, Diabetic Foot Ulcer (DFU)1
Limb Preservation Platform, IncVenous Leg Ulcer (VLU)1
Neuro Pain Medical CenterAgitation, Alzheimer's Type Dementia1
Neuro Pain Medical CenterMigraine1
Neurocrine Clinical SiteBipolar Disorder, Major Depressive Disorder, Schizoaffective Disorder1
North Point Surgery CenterLumbar Spinal Stenosis1
Ohio State University TelemedicineAdvanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma, Stage II Pancreatic Cancer AJCC v81
Optimal Medical GroupOsteoarthritis, Knee1
Rao DermatologyAlopecia Areata1
Renaissance Surgery CenterLumbar Spinal Stenosis1

Active & Upcoming Studies in Fresno (2026)

Recruiting trials in Fresno grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Cardiovascular (1 active study)

Common conditions studied in Fresno

  • ARDS (5 active studies). Recruiting ARDS studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • ARDS (Acute Respiratory Distress Syndrome) (4 active studies). Recruiting ARDS (Acute Respiratory Distress Syndrome) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Acute Respiratory Distress Syndrome (4 active studies). Recruiting Acute Respiratory Distress Syndrome studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Acute Respiratory Distress Syndrome (ARDS) (4 active studies). Recruiting Acute Respiratory Distress Syndrome (ARDS) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Breast Cancer (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
  • Stage IIIB Lung Cancer AJCC v8 (4 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.

Leading research sponsors in Fresno

  • National Cancer Institute (NCI)
  • Alliance for Clinical Trials in Oncology
  • NRG Oncology
  • SWOG Cancer Research Network
  • Pfizer

Local regulations and guidelines

Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Fresno. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Fresno

Hipa.ai aggregates every recruiting study in Fresno from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Fresno?

There are approximately 116 recruiting clinical trials in Fresno, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Fresno pay participants?

Most recruiting trials in Fresno compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Fresno?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Fresno?

The most common conditions under active study in Fresno include ARDS (5), ARDS (Acute Respiratory Distress Syndrome) (4), Acute Respiratory Distress Syndrome (4), Acute Respiratory Distress Syndrome (ARDS) (4), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Fresno?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Fresno on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Fresno?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Fresno?

Recruiting research sites in Fresno include Kaiser Permanente-Fresno, Kaiser Permanente Fresno Orchard Plaza, Fresno Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Fresno right now?

The largest active categories in Fresno are Cancer & tumors (48), Neurology & pain (12), Diabetes & metabolic (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

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Related healthcare resources in California

Trials by condition in Fresno