Paid Clinical Trials in Grand Rapids, MI
As of June 2026, 447 paid clinical trials are recruiting in Grand Rapids, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Grand Rapids offers studies at sites including Corewell Health Grand Rapids Hospitals - Butterworth Hospital for conditions such as Colorectal Cancer, Advanced Solid Tumor, Advanced Solid Tumors, Breast Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Grand Rapids
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Grand Rapids has approximately 447 recruiting research studies across a wide range of therapeutic areas. Michigan hosts University of Michigan Health, Henry Ford Health, and Corewell Health, running trials across oncology, neurology, and cardiology with a strong focus on precision medicine.
Top Research Study Locations in Grand Rapids
Researchers run research studies in Grand Rapids, MI at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer | 67 |
| Trinity Health Grand Rapids Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Advanced Lung Non-Small Cell Carcinoma | 64 |
| START Midwest | Advanced Solid Tumor, Colorectal Cancer, Endometrial Cancer | 61 |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Malignant Solid Neoplasm, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 55 |
| Corewell Health | Amblyopia, Atrial Fibrillation, Large B-cell Lymphoma | 44 |
| Helen DeVos Children's Hospital | Neuroblastoma, Cystic Fibrosis, Focal Segmental Glomerulosclerosis | 19 |
| BAMF Health | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Prostate Cancer | 9 |
| Helen DeVos Children's Hospital at Spectrum Health | Muscular Atrophy, Spinal, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| Spectrum Health at Butterworth Campus | Metastatic Malignant Neoplasm in the Brain, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| Cancer and Hematology Centers of Western Michigan | Diffuse Large B-cell Lymphoma (DLBCL), Limited-stage Small Cell Lung Cancer (LS-SCLC), Metastatic Breast Cancer | 8 |
| START Midwest, LLC | Advanced Breast Cancer, Advanced NRAS-Mutant Melanoma, Advanced NRAS-Mutant Solid Tumors | 7 |
| South Texas Accelerated Research Therapeutics (START) Midwest | Advanced Solid Tumors, Colorectal Cancer, Colorectal Carcinoma | 7 |
| Foundation for Vision Research | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 6 |
| Corewell Health West | Angina Pectoris, Atrial Fibrillation, Chest Pain | 5 |
| Spectrum Health | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 5 |
| The Cancer & Hematology Centers | Breast Cancer, Carcinoma, Non-Small-Cell Lung, Colonic Diseases | 4 |
| GSK Investigational Site | Breast Neoplasms, Multiple Myeloma, Neoplasms | 4 |
| START - Midwest | Advanced Solid Tumors, Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) | 4 |
| Spectrum Health Medical Group | Bladder Cancer, Cardiovascular Diseases, Colorectal Disorders | 4 |
| Cancer & Hematology Centers of Western Michigan | Bladder Carcinoma, Breast Cancer, Cutaneous Melanoma | 4 |
| BAMF Health Inc. | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 3 |
| Healthy Heart Cardiology | Cardiovascular Disease, Heart Failure, Heart Failure With Mildly Reduced Ejection Fraction | 3 |
| Infusion Associates - Grand Rapids | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Pediatric Ophthalmology, P.C. | Amblyopia | 3 |
| Pine Rest Christian Mental Health Services | Agitation,Psychomotor, Alcohol Use Disorder, Alzheimer Dementia | 3 |
| The Cancer and Hematology Centers | B Cell Lymphoma, Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma | 3 |
| BAMF Health, Inc. | Cholesterol, Colorectal Cancer, Esophageal Cancer | 2 |
| Cancer And Hematology Centers of Western Michigan PC | Colorectal Neoplasms, Multiple Myeloma | 2 |
| Corewell Health (Spectrum) | Aortic Aneurysm, Abdominal, Aortic Stenosis | 2 |
| Corewell Health - Helen DeVos Children's Hospital (HDVCH) | Fabry Disease, Glycogen Storage Disease Type II, Pompe Disease | 2 |
| Corewell Health Butterworth Hospital | Acute Decompensated Heart Failure, Chronic Migraine in Children | 2 |
| Corewell Health Research Institute | Breast Reconstruction Surgery, Stroke | 2 |
| Corewell Health System | Aortic Dissection, Aortoiliac Occlusive Disease, Peripheral Arterial Disease | 2 |
| Corewell Health, Helen DeVos Children's Hospital | Acute Treatment of Migraine, Pediatric Migraine | 2 |
| Corewell Health, for and on behalf of Spectrum Health Hospital and Corewell Health Medical Group | Acute Treatment of Migraine, Pediatric Migraine | 2 |
| Foundation for Vision Research and Retina Specialists of Michigan, P.C. | Diabetic Retinopathy, Radiation Retinopathy, Visual Impairment | 2 |
| Grand Valley State University | Cerebral Palsy, Hemiplegia, Infantile | 2 |
| Infusion Associates | COVID, Covid19, Fabry Disease | 2 |
| START - Midwest - EDOS | Breast Cancer, Solid Tumor | 2 |
| START, Midwest | Breast Cancer, Colo-rectal Cancer, Lung Cancer (Non-Small Cell) | 2 |
| Spectrum for Health | Cerebroside Lipidosis Syndrome, Gaucher Disease, Glucocerebrosidase Deficiency Disease | 2 |
| The START Center for Cancer Care - Midwest | Advanced or Metastatic Solid Tumors, Lymphoma, Lymphoma, Non Hodgkin | 2 |
| Corewell Health - Grand Rapids - Michigan Street Northeast | Type 1 Diabetes, Lung Transplant Rejection | 2 |
| Exelixis Clinical | Extra-Pancreatic Neuroendocrine Tumor (epNET), Pancreatic Neuroendocrine Tumor (pNET), Solid Tumors | 2 |
| Trinity Health Saint Mary's | Atrial Fibrillation, Intracerebral Hemorrhage | 1 |
| #1023, START Midwest | Advanced Solid Tumor | 1 |
| ALX Center 3 | CRC (Colorectal Cancer), Colo-rectal Cancer, ESCC | 1 |
| Advanced Cardiac and Vascular Centers | Peripheral Arterial Disease | 1 |
| Alkeus Site | Autosomal Recessive Stargardt Disease 1 (ABCA4-related), Stargardt Disease, Stargardt Macular Degeneration | 1 |
| BAMF Healthcare | Coronary Artery Disease | 1 |
Active & Upcoming Studies in Grand Rapids (2026)
Recruiting trials in Grand Rapids grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (239 active studies)
- A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer · Phase 1 · Aktis Oncology, Inc.
- Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE) · Phase 2, Phase 3 · GE Healthcare
Cardiovascular (25 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Neurology & pain (14 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Eye & vision (8 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Mental health & behavior (6 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (4 active studies)
Pediatric (3 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine · Phase 3 · H. Lundbeck A/S
Vaccines (1 active study)
- Outpatient Treatment With Anti-Coronavirus Immunoglobulin · Phase 3 · University of Minnesota
Common conditions studied in Grand Rapids
- Colorectal Cancer (15 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Advanced Solid Tumor (14 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumors (14 active studies). Recruiting Advanced Solid Tumors studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (12 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Ovarian Cancer (10 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Colorectal Neoplasms (9 active studies). Recruiting Colorectal Neoplasms studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Grand Rapids
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- AstraZeneca
- Children's Oncology Group
- Merck Sharp & Dohme LLC
Local regulations and guidelines
Clinical trials in Michigan are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Michigan research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Grand Rapids. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Grand Rapids
Hipa.ai aggregates every recruiting study in Grand Rapids from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Grand Rapids?
There are approximately 447 recruiting clinical trials in Grand Rapids, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Grand Rapids pay participants?
Most recruiting trials in Grand Rapids compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Grand Rapids?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Grand Rapids?
The most common conditions under active study in Grand Rapids include Colorectal Cancer (15), Advanced Solid Tumor (14), Advanced Solid Tumors (14), Breast Cancer (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Grand Rapids?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Grand Rapids on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Grand Rapids?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Grand Rapids?
Recruiting research sites in Grand Rapids include Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Trinity Health Grand Rapids Hospital, START Midwest, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Grand Rapids right now?
The largest active categories in Grand Rapids are Cancer & tumors (239), Cardiovascular (25), Neurology & pain (14). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.