Clinical Trials at University of California, Irvine
As of August 2026, 31 paid clinical trials are recruiting at University of California, Irvine, located at MEDICAL PLAZA DR, ROOM 1619, IRVINE, CA 92697-0001, phone (949) 824-8334 in Irvine, California. Active studies at this site cover conditions such as Breast Cancer, Endometrial Cancer and Multiple Myeloma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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31 clinical trials at University of California, Irvine
·Clear filters·A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Onyx™ Liquid Embolic IDE Clinical Study
A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma
A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)
Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer
Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease
MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)
I CAN DO Surgical ACP
Neoadjuvant Nivolumab + Relatlimab (Opdualag) Versus Nivolumab for Resectable High-Risk Basal Cell Carcinoma
ASSESS ALL ALS Study
Clinical Procedures to Support Research in ALS
Telerehabilitation In The Home After Stroke
Regeneron AA Multicenter (Dupilumab)
My Life and My Experiences Project
An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms
Dupilumab in the Treatment of Pediatric Alopecia Areata
Biomarker Exploration in Aging, Cognition and Neurodegeneration
AWARE: Management of ADHD in Autism Spectrum Disorder
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors
Exercise in Child Health
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
A Biobehavioral Intervention for Latino/Hispanic Young Adults with Cancer
Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)
Common conditions studied in Irvine
- Breast Cancer (12 active studies)
- Endometrial Cancer (9 active studies)
- Multiple Myeloma (9 active studies)
- Anatomic Stage IV Breast Cancer AJCC v8 (7 active studies)
- Alzheimer Disease (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (6 active studies)
Leading research sponsors in Irvine
- National Cancer Institute (NCI)
- University of California, Irvine
- City of Hope Medical Center
- Eli Lilly and Company
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Irvine?
There are approximately 375 recruiting clinical trials in Irvine, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Irvine pay participants?
Most recruiting trials in Irvine compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Irvine?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Irvine?
The most common conditions under active study in Irvine include Breast Cancer (12), Endometrial Cancer (9), Multiple Myeloma (9), Anatomic Stage IV Breast Cancer AJCC v8 (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Irvine?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Irvine on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Irvine?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Irvine?
Recruiting research sites in Irvine include City of Hope at Irvine Lennar, UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, University of California, Irvine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Irvine right now?
The largest active categories in Irvine are Cancer & tumors (192), Neurology & pain (24), Diabetes & metabolic (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of California, Irvine?
University of California, Irvine is located at MEDICAL PLAZA DR, ROOM 1619, IRVINE, CA 92697-0001. Use the Google Maps link in the intro above to get directions.
How do I contact University of California, Irvine?
You can reach University of California, Irvine by phone at (949) 824-8334. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.