Safety and Efficacy of NeuroTechR3 System for Upper Extremity Recovery After Stroke
for Stroke
1 location in Jacksonville
Sponsor: Brooks Rehabilitation
Sex: All·Age: 18+
Code: NCT07769281·Recruiting·Listed Aug 17, 2026
Brain disorders Clinical Trials in Jacksonville, FL
As of August 2026, 41 paid clinical trials are recruiting for Brain disorders in Jacksonville, Florida. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Jacksonville
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
42 clinical trials for Brain disorders
·Clear filters· Email me when a new brain disorders trial opens in Jacksonville, FL.
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
for Alzheimer Disease
Drug: Donanemab
Sites in Jacksonville, Port Orange +50 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 55+
Code: NCT07602582·Phase 3·Recruiting·Listed May 2026
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
for Cognitive Dysfunction
Drug: Donanemab
Sites in Jacksonville, Gainesville +40 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 55 - 85
Code: NCT07589595·Phase 2·Recruiting·Listed May 2026
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
for Acute Stroke
Sites in Jacksonville, Tampa +34 more locations
Sponsor: DiaMedica Therapeutics Inc
Sex: All·Age: 18 - 90
Code: NCT05065216·Phase 2, Phase 3·Recruiting·Listed Oct 2021
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
for Stroke
Sites in Jacksonville, Tampa +29 more locations
Sponsor: W.L.Gore & Associates
Sex: All·Age: 18 - 70
Code: NCT03821129·Recruiting·Listed Jan 2019
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
for Alzheimer's Disease
Drug: KarXT
Sites in Jacksonville, Lady Lake +23 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 60 - 85
Code: NCT06976203·Phase 3·Recruiting·Listed May 2025
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)
for Generalized Myasthenia Gravis
Sites in Jacksonville, Gainesville +30 more locations
Sponsor: Alexion Pharmaceuticals, Inc.
Sex: All·Age: 18+
Code: NCT04202341·Recruiting·Listed Dec 2019
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
for Amyotrophic Lateral Sclerosis
Sites in Jacksonville, Tampa +16 more locations
Sponsor: Prilenia
Sex: All·Age: 18 - 80
Code: NCT07322003·Phase 3·Recruiting·Listed Jan 2026
Diagnosing Epilepsy To EffeCT Change
for Epilepsy
Sites in Jacksonville, Tampa +17 more locations
Sponsor: Epiminder America, Inc.
Sex: All·Age: 18 - 75
Code: NCT07110337·Recruiting·Listed Aug 2025
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
for Generalized Myasthenia Gravis
Sites in Jacksonville, Altamonte Springs +17 more locations
Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Sex: All·Age: 18+
Code: NCT06463587·Phase 3·Recruiting·Listed Jun 2024
Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up
for Epilepsy
Sites in Jacksonville, Tampa +14 more locations
Sponsor: Epiminder America, Inc.
Sex: All·Age: 18 - 75
Code: NCT07110454·Recruiting·Listed Aug 2025
Pilot/Pivotal Study of DBS+Rehab After Stroke
for Stroke
Sites in Jacksonville +8 more locations
Sponsor: Enspire DBS Therapy, Inc.
Sex: All·Age: 21+
Code: NCT05701280·Recruiting·Listed Jan 2023
EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment
for Ischemic Stroke
Sites in Jacksonville +13 more locations
Sponsor: BrainQ Technologies Ltd.
Sex: All·Age: 22 - 80
Code: NCT06386874·Recruiting·Listed Apr 2024
Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS
for Amyotrophic Lateral Sclerosis
Sites in Jacksonville, Miami +5 more locations
Sponsor: Vector Y Therapeutics
Sex: All·Age: 18+
Code: NCT07287397·Phase 1, Phase 2·Recruiting·Listed Dec 2025
Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
for Alzheimer Disease
Sites in Jacksonville +2 more locations
Sponsor: MMI (Medical Microinstruments, Inc.)
Sex: All·Age: 50+
Code: NCT07178210·Recruiting·Listed Sep 2025
Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy
for Epilepsy
Sites in Jacksonville & Miami
Sponsor: Supernus Pharmaceuticals, Inc.
Sex: All·Age: 18 - 70
Code: NCT05518578·Phase 2·Recruiting·Listed Aug 2022
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
for Intracerebral Hemorrhage
Sites in Jacksonville, Gainesville +47 more locations
Sponsor: Joseph Broderick, MD
Sex: All·Age: 18 - 80
Code: NCT07227246·Phase 3·Recruiting·Listed Nov 2025
PREVENT ALL ALS Study
for Amyotrophic Lateral Sclerosis
Sites in Jacksonville +30 more locations
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06581861·Recruiting·Listed Sep 2024
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
for Frontotemporal Lobar Degeneration (FTLD)
Sites in Jacksonville +24 more locations
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT04363684·Recruiting·Listed Apr 2020
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
for Stroke
Sites in Jacksonville, Port Saint Lucie +26 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT05907629·Recruiting·Listed Jun 2023
The Fourth Left Atrial Appendage Occlusion Study
for Atrial Fibrillation
Sites in Jacksonville, Ocala +45 more locations
Sponsor: Hamilton Health Sciences Corporation
Sex: All·Age: 18+
Code: NCT05963698·Recruiting·Listed Jul 2023
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
for Cognitive Impairment, Mild
Sites in Jacksonville, Gainesville +89 more locations
Sponsor: Duke University
Sex: All·Age: 75+·Accepts healthy volunteers
Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020
Diagnostic Performance Study of the EMVision Emu™ Brain Scanner in the Detection of Intracranial Hemorrhage in Suspected Stroke Patients
for Stroke
Sites in Jacksonville +5 more locations
Sponsor: EMVision Medical Devices Ltd
Sex: All·Age: 22+
Code: NCT06999122·Recruiting·Listed May 2025
ASSESS ALL ALS Study
for Amyotrophic Lateral Sclerosis
Sites in Jacksonville, Davie +34 more locations
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06578195·Recruiting·Listed Aug 2024
RESPARK - Brain Q for Chronic Stroke
for Stroke
1 location in Jacksonville
Sponsor: University of Florida
Sex: All·Age: 18 - 80
Code: NCT07095920·Recruiting·Listed Jul 2025
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
for Intracerebral Hemorrhage
Sites in Jacksonville, Tampa +140 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019
Dominantly Inherited Alzheimer Network (DIAN)
for Alzheimer's Disease
Sites in Jacksonville +6 more locations
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT00869817·Recruiting·Listed Mar 2009
Telerehabilitation In The Home After Stroke
for Stroke
Sites in Jacksonville, Miami +25 more locations
Sponsor: University of California, Los Angeles
Sex: All·Age: 18 - 80
Code: NCT06682429·Recruiting·Listed Nov 2024
Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
for Cognitive Dysfunction
Sites in Jacksonville & Gainesville
Sponsor: University of Florida
Sex: All·Age: 65+
Code: NCT05830942·Recruiting·Listed Apr 2023
A Study of Ranolazine in ALS
for Amyotrophic Lateral Sclerosis
Sites in Jacksonville +5 more locations
Sponsor: Swathy Chandrashekhar, MBBS
Sex: All·Age: 18+
Code: NCT06527222·Phase 2·Recruiting·Listed Jul 2024
Responses to Backward Walking Training Post-Stroke
for Stroke
Sites in Jacksonville & Gainesville
Sponsor: VA Office of Research and Development
Sex: All·Age: 18 - 90
Code: NCT04928482·Recruiting·Listed Jun 2021
Stroke Thrombectomy and Aneurysm Registry
for Stroke
Sites in Jacksonville, Gainesville +52 more locations
Sponsor: Medical University of South Carolina
Sex: All·Age: 1 - 120
Code: NCT04994756·Recruiting·Listed Aug 2021
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
for Ischemic Stroke
Sites in Jacksonville, Miami +26 more locations
Sponsor: Massachusetts General Hospital
Sex: All·Age: 18+
Code: NCT04916210·Recruiting·Listed Jun 2021
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
for Amyotrophic Lateral Sclerosis
Sites in Jacksonville +9 more locations
Sponsor: Target ALS Foundation, Inc.
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05137665·Recruiting·Listed Nov 2021
Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
for Amyotrophic Lateral Sclerosis
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05116943·Recruiting·Listed Nov 2021
Globus Pallidus Stimulation to Treat Insomnia
for Parkinson Disease
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 40 - 80
Code: NCT04116996·Recruiting·Listed Oct 2019
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease
for Alzheimer Disease
Sites in Jacksonville +1 more location
Sponsor: Mayo Clinic
Sex: Female·Age: 60+·Accepts healthy volunteers
Code: NCT03821857·Phase 4·Recruiting·Listed Jan 2019
Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders
for Amyotrophic Lateral Sclerosis
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05474235·Recruiting·Listed Jul 2022
Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait
for Spinal Cord Injury
Sites in Jacksonville & Tampa
Sponsor: Brooks Rehabilitation
Sex: All·Age: 18+
Code: NCT07164846·Recruiting·Listed Sep 2025
Non-invasive Nerve Stimulation for PTSD and Sleep
for Post Traumatic Stress Disorder
Sites in Jacksonville & Gainesville
Sponsor: University of Florida
Sex: All·Age: 18 - 55·Accepts healthy volunteers
Code: NCT03170440·Recruiting·Listed May 2017
The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis
for Myasthenia Gravis
Sites in Jacksonville +9 more locations
Sponsor: Ad scientiam
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05564936·Recruiting·Listed Oct 2022
Top Research Study Locations in Jacksonville
Researchers run research studies in Jacksonville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic in Florida | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 170 |
| Mayo Clinic | Amyotrophic Lateral Sclerosis, Colorectal Cancer, Breast Cancer | 83 |
| Mayo Clinic Florida | Amyotrophic Lateral Sclerosis, Advanced Melanoma, CRC | 75 |
| Mayo Clinic Jacksonville | Non Small Cell Lung Cancer, Amyotrophic Lateral Sclerosis (ALS), Prostate Cancer | 47 |
| Nemours Children's Clinic-Jacksonville | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 32 |
| Jacksonville Center for Clinical Research | Heart Failure, Obesity, Cardiovascular Disease | 22 |
| Baptist MD Anderson Cancer Center | Breast Cancer, Advanced Melanoma, Anatomic Stage II Breast Cancer AJCC v8 | 18 |
| Cancer Specialists of North Florida | Carcinoma, Non-Small-Cell Lung, Acinar Cell Carcinoma, Advanced Cancer | 14 |
| University of Florida | Coronary Artery Disease, Allergies, Arthropathy of Hip | 12 |
| Mayo Clinic - Jacksonville | Adenoid Cystic Carcinoma, Amyloid Cardiomyopathy, Amyloidosis | 10 |
| Brooks Rehabilitation | Spinal Cord Injuries, Spinal Cord Injury, Stroke | 9 |
| Ascension St. Vincent's | Atrial Fibrillation, Brain Tumor, Brain Tumor - Metastatic | 8 |
| Mayo Clinic - Florida | Epilepsy, Epilepsy (Treatment Refractory), Astrocytoma, Grade IV | 8 |
| University of Florida Jacksonville | Coronary Artery Disease, AV Block, Acute Stroke | 8 |
| Baptist Health Research Institute | Acute Ischemic Stroke, Alzheimer Disease, Aneurysm, Intracranial | 7 |
| UF Health Jacksonville | Atrial Fibrillation, Diabetes Mellitus, Type 2, Heart Failure | 7 |
| Baptist Medical Center Jacksonville | Intracranial Aneurysm, Chronic Subdural Hematoma, Intracranial Atherosclerotic Stenosis (ICAS) | 6 |
| Clinical Neuroscience Solutions, Inc. | Bipolar Depression, Bipolar Disorder, Bipolar I Disorder | 6 |
| Mayo Clinic Cancer Center | Acute Myeloid Leukemia, B-Cell Acute Lymphoblastic Leukaemia, CRC | 6 |
| First Coast Cardiovascular Institute | Heart Failure, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia | 5 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Gastrointestinal Neoplasms, Irritable Bowel Syndrome | 5 |
| Nemours Children's Clinic | Cystic Fibrosis, Amblyopia, Cystic Fibrosis Pulmonary Exacerbation | 5 |
| Nemours Children's Health | Asthma (Diagnosis), Autosomal Dominant Hypocalcemia Type 1 (ADH1), Child | 5 |
| Clinical Trial Site | ATTR Amyloidosis, Advanced Hepatocellular Carcinoma, Generalized Myasthenia Gravis | 4 |
| Brooks Rehabilitation Hospital | Internuclear Ophthalmoplegia, Ischemic Stroke, Palsy, Abducens | 4 |
Active & Upcoming Studies in Jacksonville (2026)
Recruiting trials in Jacksonville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (302 active studies)
Cardiovascular (68 active studies)
Neurology & pain (53 active studies)
- Magnesium Supplement for Sleep Quality in Women With Poor Sleep · Jacksonville University
- Arm Elevation for Prevention of Propofol Injection Pain · Mayo Clinic
Diabetes & metabolic (49 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight · Phase 3 · Novo Nordisk A/S
Mental health & behavior (16 active studies)
- A Study to Evaluate the Efficacy and Safety of AXS-05 for Smoking Cessation in Adults · Phase 3 · Axsome Therapeutics, Inc.
- A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder · Phase 3 · Otsuka Pharmaceutical Development & Commercialization, Inc.
HIV / STI (8 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System · University of Florida
Eye & vision (8 active studies)
- Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration · Phase 2 · Adverum Biotechnologies, Inc.
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (6 active studies)
Vaccines (2 active studies)
Common conditions studied in Jacksonville
- Obesity (20 active studies)
- Malignant Solid Neoplasm (19 active studies)
- Breast Cancer (16 active studies)
- Heart Failure (16 active studies)
- Overweight (14 active studies)
- Prostate Cancer (13 active studies)
Leading research sponsors in Jacksonville
- Mayo Clinic
- AstraZeneca
- University of Florida
- Children's Oncology Group
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Jacksonville?
There are approximately 925 recruiting clinical trials in Jacksonville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Jacksonville pay participants?
Most recruiting trials in Jacksonville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Jacksonville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Jacksonville?
The most common conditions under active study in Jacksonville include Obesity (20), Malignant Solid Neoplasm (19), Breast Cancer (16), Heart Failure (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Jacksonville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Jacksonville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Jacksonville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Jacksonville?
Recruiting research sites in Jacksonville include Mayo Clinic in Florida, Mayo Clinic, Mayo Clinic Florida, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Jacksonville right now?
The largest active categories in Jacksonville are Cancer & tumors (302), Cardiovascular (68), Neurology & pain (53). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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