Colorectal cancer Clinical Trials in Pittsburgh, PA
As of September 2026, 18 paid clinical trials are recruiting for Colorectal cancer in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Pittsburgh
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18 clinical trials for Colorectal cancer
·Clear filters·A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar
A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
Top Research Study Locations in Pittsburgh
Researchers run research studies in Pittsburgh, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pittsburgh | Stroke, Traumatic Brain Injury, Dementia | 155 |
| UPMC Hillman Cancer Center | Melanoma, Metastatic Malignant Solid Neoplasm, Acute Myeloid Leukemia | 147 |
| University of Pittsburgh Medical Center | Chronic Pancreatitis, Cystic Fibrosis, Advanced Solid Tumor | 132 |
| Allegheny General Hospital | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Heart Failure | 64 |
| Children's Hospital of Pittsburgh of UPMC | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Neuroblastoma | 58 |
| UPMC Children's Hospital of Pittsburgh | Fabry Disease, Cerebral Palsy, Congenital Bone Marrow Failure Syndromes | 53 |
| Allegheny Health Network | Brain Tumor, Breast Cancer, Colorectal Cancer | 33 |
| UPMC-Passavant Hospital | Anatomic Stage II Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Stage IV Renal Cell Cancer AJCC v8 | 31 |
| UPMC-Saint Clair Hospital Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma, Stage III Laryngeal Cancer AJCC v8 | 26 |
| UPMC-Saint Margaret | Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | 24 |
| West Penn Hospital | Large B-cell Lymphoma, Stage IV Colorectal Cancer AJCC v8, Acute Lymphoblastic Leukemia (ALL) | 23 |
| UPMC Presbyterian | Acute Kidney Injuries, Aneurysm of Aorta, Thoracic, Aneurysmal Disease | 20 |
| UPMC-Magee Womens Hospital | Anatomic Stage II Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Anatomic Stage I Breast Cancer AJCC v8 | 20 |
| UPMC Presbyterian Hospital | Abdominal Surgery, Acute Ischemic Stroke, Acute Myocardial Infarction | 19 |
| VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA | Cardiovascular Diseases, Stroke, Acute Kidney Injury | 19 |
| UPMC | Focal Epilepsy, ASD - Atrial Septal Defect, Advanced Melanoma | 18 |
| UPMC-Shadyside Hospital | Head and Neck Squamous Cell Carcinoma, Stage II Lip and Oral Cavity Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8 | 18 |
| University of Pittsburgh Cancer Institute (UPCI) | Head and Neck Squamous Cell Carcinoma, Metastatic Renal Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma | 16 |
| Children's Hospital of Pittsburgh | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Adolescent Congenital Heart Disease | 13 |
| University of Pittsburgh Medical Center (UPMC) | ALS, ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis | 9 |
| AHN Allegheny General Hospital | Breast Cancer, Cancer, Carcinoma, Non-Small-Cell Lung | 8 |
| AHN West Penn Hospital | Malignant Mesothelioma, Malignant Pleural Effusion, Metastasis to Pleura | 8 |
| UPMC Magee-Womens Hospital | ADHD, Behavioral Intervention, Cervical Cancer | 8 |
| University of Pittsburgh School of Medicine | Adolescents, Anorexia Nervosa, Bipolar Disorder (BD) | 8 |
| UPMC Shadyside Hospital | Abdominal Surgery, Dementia, Harm Reduction | 7 |
Active & Upcoming Studies in Pittsburgh (2026)
Recruiting trials in Pittsburgh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (396 active studies)
- Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · University of Pittsburgh
- A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information · Children's Oncology Group
Neurology & pain (81 active studies)
- Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · University of Pittsburgh
- Psilocybin After Trauma Surgery for Pain · Phase 1 · Trent Emerick
Cardiovascular (74 active studies)
- TEPH: Telaglenastat Efficacy in Pulmonary Hypertension · Phase 1, Phase 2 · Chan, Stephen, MD, PhD
- Precision Analgesia for Cardiac Surgery · Kathirvel Subramaniam
Diabetes & metabolic (39 active studies)
- Technology Knowledge Optimization for Type 1 Diabetes in Schools · University of Pittsburgh
- Network-Based Support to Help Community Coalition Members Choose and Use Strategies to Improve Child Health · University of Pittsburgh
Mental health & behavior (37 active studies)
Pediatric (19 active studies)
- Hypoxic Red Blood Cells in Sickle Cell Anemia · Hemanext
- A Multicenter Study to Assess the Feasibility of 5-Aminolevulinic Acid (5-ALA) in Pediatric Brain Tumor Patients · Phase 2 · Costas Hadjipanayis
HIV / STI (8 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (7 active studies)
Eye & vision (3 active studies)
- A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults · Astellas Pharma Global Development, Inc.
- The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease · Rinsada
Common conditions studied in Pittsburgh
- Breast Cancer (24 active studies)
- Cancer (19 active studies)
- Ovarian Cancer (17 active studies)
- Endometrial Cancer (16 active studies)
- Stroke (16 active studies)
- Melanoma (15 active studies)
Leading research sponsors in Pittsburgh
- University of Pittsburgh
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Pittsburgh?
There are approximately 1,240 recruiting clinical trials in Pittsburgh, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Pittsburgh pay participants?
Most recruiting trials in Pittsburgh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Pittsburgh?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Pittsburgh?
The most common conditions under active study in Pittsburgh include Breast Cancer (24), Cancer (19), Ovarian Cancer (17), Endometrial Cancer (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Pittsburgh?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Pittsburgh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Pittsburgh?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Pittsburgh?
Recruiting research sites in Pittsburgh include University of Pittsburgh, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Pittsburgh right now?
The largest active categories in Pittsburgh are Cancer & tumors (396), Neurology & pain (81), Cardiovascular (74). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.