Paid Clinical Trials in Sacramento, CA

As of June 2026, 617 paid clinical trials are recruiting in Sacramento, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Sacramento offers studies at sites including University of California Davis Comprehensive Cancer Center for conditions such as Breast Cancer, Heart Failure, Acute Myeloid Leukemia, Atopic Dermatitis. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Trials by specialty in Sacramento

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About research studies in Sacramento

Sacramento has approximately 617 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.

Top Research Study Locations in Sacramento

Researchers run research studies in Sacramento, CA at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
University of California Davis Comprehensive Cancer CenterStage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Advanced Malignant Solid Neoplasm106
Mercy Cancer Center - SacramentoAnatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer44
Sutter Medical Center SacramentoAnatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v839
UC Davis Medical CenterHeart Failure, Intracerebral Hemorrhage, Acute Decompensated Heart Failure37
University of California, DavisOligoprogressive, Amblyopia, Amyotrophic Lateral Sclerosis36
Kaiser Permanente-South SacramentoStage IIIB Lung Cancer AJCC v8, Breast Cancer, Acute Myeloid Leukemia35
Kaiser Permanente Downtown CommonsStage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Breast Cancer34
UC Davis HealthHeart Failure, Acute Pain, Anterior Cruciate Ligament Rupture23
University of California DavisAdenovirus Infections, Advanced Lung Carcinoma, Breast Cancer20
South Sacramento Cancer CenterBreast Cancer, Ovarian Carcinoma, Stage II Lung Cancer AJCC v816
UC DavisVon Willebrand Disease, Type 3, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia15
University of California Davis HealthArticular Cartilage Defect, Articular Cartilage Disorder of Knee, COVID-19 Infection12
University of California Davis Medical CenterAbdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder), Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder)12
University of California, Davis Comprehensive Cancer CenterAdvanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor11
Integrative Skin Science and ResearchAtopic Dermatitis, Atopic, Collagen Degeneration10
Sutter Institute for Medical ResearchAcute Ischemic Stroke, Bladder Carcinoma, Breast Cancer9
University of California, Davis Medical CenterAbdomen Injury, Abdomen, Acute, Abdominal Injury9
UC Davis Comprehensive Cancer CenterAbdominal Neoplasm, Advanced Solid Tumors, Avascular Necrosis8
University of California, Davis - Dermatology DepartmentScarring, Actinic Keratoses, Alopecia Areata8
Kaiser Permanente Sacramento Medical CenterAtrial Fibrillation, B Acute Lymphoblastic Leukemia, Intracerebral Hemorrhage8
Retinal Consultants Medical GroupDiabetic Macular Edema, Geographic Atrophy, Age-Related Macular Degeneration7
UC Davis MIND InstituteADHD, Attention Deficit Hyperactivity Disorder, Down Syndrome7
University of California Davis Health SystemCOVID-19, Coagulation Disorder, Coronary Artery Disease6
UC Davis Children's HospitalAbdominal Pain, Ductus Arteriosus, Patent, Gastroschisis5
UC Davis EXPLORER Molecular Imaging CenterBreast Cancer, Cardiovascular Disease, Chronic Low-back Pain (cLBP)5
Golden State UrologyBenign Prostatic Hyperplasia, Benign Prostatic Hyperplasia (BPH), Kidney Calculi; Ureteral Calculi4
Retinal Consultants Medical Group IncMacular Edema Secondary to Inflammation, Geographic Atrophy, Geographic Atrophy Secondary to Age-related Macular Degeneration4
Sutter Medical CenterAcute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Aortic Stenosis4
University of California - DavisAMD, Alzheimer Disease, Huntington's Disease4
University of California Davis (UC Davis) Comprehensive Cancer CenterCarcinoma, Transitional Cell, Multiple Myeloma, Neoplasm Metastasis4
University of California Davis Medical Center - Pulmonary MedicineARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome4
University of California at DavisCOPD, Contraception, Dystonia4
University of California-DavisDegenerative Disc Disease, Diabetes Mellitus, Type 1, Metastatic Castration-resistant Prostate Cancer4
VA Northern California Health Care System, Mather, CACarcinoma, Hepatocellular, Cirrhosis, Cognitive Dysfunction4
University of California, Davis MIND InstituteAutism, Autism Spectrum Disorder, Intellectual Disability3
Imaging Research CenterFirst Episode Psychosis (FEP), Healthy, Schizophrenia3
Sutter HealthAortic Aneurysm, Aortic Diseases, Aortic Dissection3
The University of California Davis Comprehensive Cancer CenterBrain Metastases, Lung Cancer, Lung Cancer Metastatic3
UC Davis Health Eye CenterAMD, Age-related Macular Degeneration (AMD), CNV3
UC Davis Health Medical CenterInterstitial Lung Disease, Progressive Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis3
Clinical Trials ResearchAlzheimer Disease, Dementia, Diabetic Peripheral Neuropathic Pain3
Akero Clinical Study SiteMASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis2
Ascendis Investigational SiteGrowth Hormone Deficiency2
California Pacific Medical CenterGeneralized Myasthenia Gravis2
Care Access - SacramentoObesity, Overweight2
Center Of Excellence in Diabetes and EndocrinologyIdiopathic Short Stature2
Covered CaliforniaBehavioral Economics, Health Insurance, Outreach Intervention2
GSK Investigational SiteChickenpox, Hepatitis B2
Integrative Research InstituteAcne Vulgaris, Collagen Degeneration, Elastic Skin2
Integrative Skin and ResearchRosacea, Acne, Melasma2

Active & Upcoming Studies in Sacramento (2026)

Recruiting trials in Sacramento grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Neurology & pain (35 active studies)

Mental health & behavior (7 active studies)

Common conditions studied in Sacramento

  • Breast Cancer (13 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
  • Heart Failure (11 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
  • Acute Myeloid Leukemia (10 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
  • Atopic Dermatitis (10 active studies). Atopic dermatitis studies test IL-13 inhibitors, JAK inhibitors, and next-generation topical therapies for moderate-to-severe eczema.
  • Stage IV Lung Cancer AJCC v8 (9 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
  • Multiple Myeloma (7 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.

Leading research sponsors in Sacramento

  • University of California, Davis
  • National Cancer Institute (NCI)
  • SWOG Cancer Research Network
  • NRG Oncology
  • Alliance for Clinical Trials in Oncology

Local regulations and guidelines

Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Sacramento. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Sacramento

Hipa.ai aggregates every recruiting study in Sacramento from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Sacramento?

There are approximately 617 recruiting clinical trials in Sacramento, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Sacramento pay participants?

Most recruiting trials in Sacramento compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Sacramento?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Sacramento?

The most common conditions under active study in Sacramento include Breast Cancer (13), Heart Failure (11), Acute Myeloid Leukemia (10), Atopic Dermatitis (10), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Sacramento?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Sacramento on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Sacramento?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Sacramento?

Recruiting research sites in Sacramento include University of California Davis Comprehensive Cancer Center, Mercy Cancer Center - Sacramento, Sutter Medical Center Sacramento, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Sacramento right now?

The largest active categories in Sacramento are Cancer & tumors (216), Neurology & pain (35), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

Browse more clinical trials

Related healthcare resources in California

Trials by condition in Sacramento