Paid Clinical Trials in San Jose, CA
As of June 2026, 87 paid clinical trials are recruiting in San Jose, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
San Jose offers studies at sites including Kaiser Permanente-Santa Teresa-San Jose for conditions such as Asthma, Major Depressive Disorder, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in San Jose
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·Clear filters·↓ Download CSVAbout research studies in San Jose
San Jose has approximately 87 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in San Jose
Researchers run research studies in San Jose, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Kaiser Permanente-Santa Teresa-San Jose | Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Breast Cancer | 37 |
| Stanford Cancer Center South Bay | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Early Stage Triple-Negative Breast Carcinoma | 10 |
| Kaiser Permanente San Jose | Clostridioides Difficile Associated Disease, Diabetes Mellitus, Type 2, Hypoglycemia | 3 |
| Vanda Investigational Site | Major Depressive Disorder (MDD), Nausea and Vomiting, Obesity | 3 |
| Kaiser Permanente | Barrett Esophagus, Barretts Esophagus With Dysplasia, Cardiovascular Diseases | 2 |
| Lumos Clinical Research Center | Major Depressive Disorder, Schizophrenia | 2 |
| Lumos Clinical Research Center LLC | Depressive Disorder, Major | 2 |
| Prodigy Psychiatric Group | Attention Deficit Disorder (ADD), Attention Deficit Disorder With Hyperactivity (ADHD), Attention Deficit Hyperactivity Disorder (ADHD) | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, NASH - Nonalcoholic Steatohepatitis | 1 |
| Aligos Investigational Site | Chronic Hepatitis B Infection | 1 |
| Allergy & Asthma Associates of Santa Clara Valley | Refractory or Unexplained Chronic Cough | 1 |
| Allergy and Asthma Associates of Santa Clara Valley Research Center | Asthma | 1 |
| Almaden Family Optometric Center | Myopia | 1 |
| Autobahn Site #119 | Major Depressive Disorder | 1 |
| California Allergy & Asthma Medical Group Inc. | Refractory or Unexplained Chronic Cough | 1 |
| Enveda Investigative Site | Asthma | 1 |
| Kaiser Permanente - San Jose Medical Center | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Kaiser Permanente Skyport Medical Offices | Primary IgA Nephropathy | 1 |
| Le's Aesthetics | Androgenic Alopecia | 1 |
| Lumos Clinical Research Center /ID# 231267 | Migraine | 1 |
| Lumos Clinical Research Center /ID# 239018 | Migraine | 1 |
| Lumos Clinical Research Center /ID# 249731 | Episodic Migraine | 1 |
| Lumos Clinical Research Center /ID# 251608 | Migraine Prophylaxis | 1 |
| Lumos Clinical Research Center /ID# 262805 | Bipolar I Disorder, Depression | 1 |
| Lumos Clinical Research Center /ID# 270582 | Chronic Migraine | 1 |
Active & Upcoming Studies in San Jose (2026)
Recruiting trials in San Jose grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (40 active studies)
- Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial · Phase 3 · Alliance for Clinical Trials in Oncology
- ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab · Phase 3 · Alliance for Clinical Trials in Oncology
Mental health & behavior (5 active studies)
- A Study of NTX-1472 in Social Anxiety Disorder · Phase 2 · Newleos Therapeutics, Inc.
- Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU) · Bristol-Myers Squibb
Diabetes & metabolic (5 active studies)
- A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use · Phase 3 · Vanda Pharmaceuticals
- SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes · Phase 2 · SAb Biotherapeutics, Inc.
Neurology & pain (5 active studies)
- A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years · Phase 3 · AbbVie
- Long-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With Migraine · Phase 3 · AbbVie
Cardiovascular (2 active studies)
- Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System · P+F Products + Features USA Inc.
- A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension · Phase 2 · Retension Pharmaceuticals. Inc.
HIV / STI (1 active study)
Eye & vision (1 active study)
- DSLT in Normal Tension Glaucoma (NTG) Asian Eyes · Ngoc Nguyen Inc.
Common conditions studied in San Jose
- Asthma (4 active studies). Asthma research tests biologic therapies targeting IL-4, IL-5, and TSLP pathways for moderate-to-severe and eosinophilic disease.
- Major Depressive Disorder (4 active studies). Major depressive disorder research examines rapid-acting agents, augmentation strategies, and digital therapeutics for treatment-resistant cases.
- Stage IIIB Lung Cancer AJCC v8 (4 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Stage IV Lung Cancer AJCC v8 (4 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Anatomic Stage I Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in San Jose
- NRG Oncology
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- SWOG Cancer Research Network
- AbbVie
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in San Jose. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in San Jose
Hipa.ai aggregates every recruiting study in San Jose from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in San Jose?
There are approximately 87 recruiting clinical trials in San Jose, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Jose pay participants?
Most recruiting trials in San Jose compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Jose?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Jose?
The most common conditions under active study in San Jose include Asthma (4), Major Depressive Disorder (4), Stage IIIB Lung Cancer AJCC v8 (4), Stage IV Lung Cancer AJCC v8 (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Jose?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Jose on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Jose?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Jose?
Recruiting research sites in San Jose include Kaiser Permanente-Santa Teresa-San Jose, Stanford Cancer Center South Bay, Kaiser Permanente San Jose, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Jose right now?
The largest active categories in San Jose are Cancer & tumors (40), Mental health & behavior (5), Diabetes & metabolic (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.