Oncology Clinical Trials in Santa Barbara, CA
As of July 2026, 20 paid clinical trials are recruiting for Oncology in Santa Barbara, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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20 clinical trials for Oncology
·Clear filters·↓ Download CSVThis Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
Galleri® in the Medicare Population.
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Molecular Genetics Studies of Cancer Patients and Their Relatives
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Project: Every Child for Younger Patients With Cancer
Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors
About research studies in Santa Barbara
Santa Barbara has approximately 68 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in Santa Barbara
Researchers run research studies in Santa Barbara, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Ridley-Tree Cancer Center | Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Advanced Esophageal Adenocarcinoma | 10 |
| Sansum Clinic | Carcinoma, Non-Small-Cell Lung, Prostate Cancer, Acinar Cell Carcinoma | 10 |
| Santa Barbara Cottage Hospital | Acute Myeloid Leukemia, Adrenal Gland Pheochromocytoma, Aortic Stenosis | 10 |
| University of California, Santa Barbara | Basic Science: Visual Attention in Healthy Participants, Basic Science: Neural Representations of Location, Attention | 5 |
| California Retina Consultants | nAMD, AMD, Gene Therapy | 4 |
| Sansum Diabetes Research Institute | Type 2 Diabetes Mellitus, Diabetes, Gestational, Gestational Diabetes | 4 |
| California Retina Consultants CRC | Diabetic Retinopathy, DR, Neovascular Age-related Macular Degeneration, Wet Macular Degeneration | 2 |
| Adverum Clinical | Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD | 1 |
| California Retina Consultants (CRC) | Neovascular Age-Related Macular Degeneration (nAMD) | 1 |
| California Retina Consultants- Santa Barbara | Diabetic Retinopathy, NPDR - Non Proliferative Diabetic Retinopathy | 1 |
| Cancer Center of Santa Barbara | Malignant Neoplasm | 1 |
| Central Valley Surg Ctr | Lumbar Spinal Stenosis | 1 |
| Coastal Surgery Center | Lumbar Spinal Stenosis | 1 |
| Cognixion | ALS (Amyotrophic Lateral Sclerosis) | 1 |
| Cognixion HQ | ALS (Amyotrophic Lateral Sclerosis), SCI - Spinal Cord Injury, Stroke | 1 |
| Cottage Health Research Institute | Aneurysm, Brain, Stroke, Thromboses, Intracranial | 1 |
| Cottage Health System - Santa Barbara Pulmonary Associates | Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension, Pulmonary Hypertension | 1 |
| Exelixis Clinical | Clear Cell Renal Cell Carcinoma (ccRCC), Colorectal Cancer (CRC), Head and Neck Squamous Cell Carcinoma (HNSCC) | 1 |
| Jeffrey S. Sager, MD Medical Corporation | Pulmonary Arterial Hypertension | 1 |
| SCRI - Sansum Clinic | Endometrioid Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer | 1 |
| Samsun Clinic - Ridley-Tree Cancer Center | Urinary Bladder Neoplasms, Urothelial Cancer | 1 |
| Sansum Clinic (Ridley Tree) | Lung Neoplasm Malignant | 1 |
| Sansum Clinic Research | Follicular Lymphoma (FL) | 1 |
| Sansum Clinic, Sutter Health | Diabetes, Nutrition | 1 |
| Santa Barbara Outpatient Surgery Center LLC | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Santa Barbara (2026)
Recruiting trials in Santa Barbara grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (30 active studies)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
- Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309) · Phase 3 · Astellas Pharma Global Development, Inc.
Cardiovascular (9 active studies)
- A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH) · Phase 3 · Insmed Incorporated
- Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) · Phase 3 · Insmed Incorporated
Eye & vision (6 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study · Phase 3 · Ocular Therapeutix, Inc.
Diabetes & metabolic (5 active studies)
- Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System · Insulet Corporation
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Neurology & pain (3 active studies)
- Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple Vision Pro · Cognixion
- Stroke Thrombectomy and Aneurysm Registry · Medical University of South Carolina
Common conditions studied in Santa Barbara
- Pulmonary Arterial Hypertension (4 active studies). Hypertension research tests new antihypertensive drug classes, renal denervation devices, and fixed-dose combinations for resistant disease.
- Basic Science: Visual Attention in Healthy Participants (3 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
- Fallopian Tube Cancer (3 active studies). Recruiting Fallopian Tube Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Neovascular Age-Related Macular Degeneration (nAMD) (3 active studies). Recruiting Neovascular Age-Related Macular Degeneration (nAMD) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Prostate Cancer (3 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Pulmonary Hypertension (3 active studies). Hypertension research tests new antihypertensive drug classes, renal denervation devices, and fixed-dose combinations for resistant disease.
Leading research sponsors in Santa Barbara
- NRG Oncology
- University of California, Santa Barbara
- AbbVie
- Children's Oncology Group
- Novartis Pharmaceuticals
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Santa Barbara. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Santa Barbara
Hipa.ai aggregates every recruiting study in Santa Barbara from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Santa Barbara?
There are approximately 68 recruiting clinical trials in Santa Barbara, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Santa Barbara pay participants?
Most recruiting trials in Santa Barbara compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Santa Barbara?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Santa Barbara?
The most common conditions under active study in Santa Barbara include Pulmonary Arterial Hypertension (4), Basic Science: Visual Attention in Healthy Participants (3), Fallopian Tube Cancer (3), Neovascular Age-Related Macular Degeneration (nAMD) (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Santa Barbara?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Santa Barbara on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Santa Barbara?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Santa Barbara?
Recruiting research sites in Santa Barbara include Ridley-Tree Cancer Center, Sansum Clinic, Santa Barbara Cottage Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Santa Barbara right now?
The largest active categories in Santa Barbara are Cancer & tumors (30), Cardiovascular (9), Eye & vision (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.