Clinical Trials at Palo Alto Medical Foundation-Santa Cruz
As of September 2026, 16 paid clinical trials are recruiting at Palo Alto Medical Foundation-Santa Cruz, located at 2025 SOQUEL AVE, 4TH FLOOR, SANTA CRUZ, CA 95062-1323, phone (831) 458-5610 in Santa Cruz, California. Active studies at this site cover conditions such as Anatomic Stage II Breast Cancer AJCC v8, Recurrent Lung Non-Small Cell Carcinoma and Stage IV Lung Cancer AJCC v8. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
16 clinical trials at Palo Alto Medical Foundation-Santa Cruz
·Clear filters·Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
Common conditions studied in Santa Cruz
- Anatomic Stage II Breast Cancer AJCC v8 (2 active studies)
- Recurrent Lung Non-Small Cell Carcinoma (2 active studies)
- Stage IV Lung Cancer AJCC v8 (2 active studies)
- Advanced Esophageal Adenocarcinoma (1 active study)
- Advanced Gastric Adenocarcinoma (1 active study)
- Advanced Gastroesophageal Junction Adenocarcinoma (1 active study)
Leading research sponsors in Santa Cruz
- SWOG Cancer Research Network
- NRG Oncology
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- University of California Santa Cruz
Frequently asked questions
How many paid clinical trials are currently recruiting in Santa Cruz?
There are approximately 21 recruiting clinical trials in Santa Cruz, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Santa Cruz pay participants?
Most recruiting trials in Santa Cruz compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Santa Cruz?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Santa Cruz?
The most common conditions under active study in Santa Cruz include Anatomic Stage II Breast Cancer AJCC v8 (2), Recurrent Lung Non-Small Cell Carcinoma (2), Stage IV Lung Cancer AJCC v8 (2), Advanced Esophageal Adenocarcinoma (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Santa Cruz?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Santa Cruz on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Santa Cruz?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Santa Cruz?
Recruiting research sites in Santa Cruz include Palo Alto Medical Foundation-Santa Cruz, Santa Cruz Radiation Oncology Medical Group, Social Science 2 Building, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Santa Cruz right now?
The largest active categories in Santa Cruz are Cancer & tumors (18), Pediatric (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Palo Alto Medical Foundation-Santa Cruz?
Palo Alto Medical Foundation-Santa Cruz is located at 2025 SOQUEL AVE, 4TH FLOOR, SANTA CRUZ, CA 95062-1323. Use the Google Maps link in the intro above to get directions.
How do I contact Palo Alto Medical Foundation-Santa Cruz?
You can reach Palo Alto Medical Foundation-Santa Cruz by phone at (831) 458-5610. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.