Paid Clinical Trials in Santa Maria, CA
As of June 2026, 55 paid clinical trials are recruiting in Santa Maria, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Santa Maria offers studies at sites including Mission Hope Medical Oncology - Santa Maria for conditions such as Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Heart Failure, Melanoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Santa Maria
Filter results
0 clinical trials
·Clear filters·↓ Download CSVAbout research studies in Santa Maria
Santa Maria has approximately 55 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in Santa Maria
Researchers run research studies in Santa Maria, CA at 14 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mission Hope Medical Oncology - Santa Maria | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Melanoma | 40 |
| FOMAT Medical Research | Acute Myocardial Infarction, Heart Failure, Obesity | 3 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease | 2 |
| Akero Clinical Study Site | MASH With Fibrosis, NASH With Fibrosis | 1 |
| Central Coast Medical Oncology | Mucositis, Nephrotoxicity, Ototoxicity | 1 |
| Clinical Study | Obesity, Overweight, Weight Maintenance | 1 |
| Comprehensive Cardiovascular Care | Heart Failure | 1 |
| Cypress Ambulatory Surgery Center | Lumbar Spinal Stenosis | 1 |
| FOMAT | Heart, Heart Failure With Preserved Ejection Fraction (HFPEF) | 1 |
| FOMAT - Comprehensive Cardiovascular Care | Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF) | 1 |
| Mission Hope Health Center | Mucositis, Nephrotoxicity, Ototoxicity | 1 |
| Santa Maria Gastroenterology - FOMAT Medical Research HyperCORE | Ulcerative Colitis | 1 |
| Santa Maria Gastroenterology Center | Metabolic Dysfunction-Associated Steatohepatitis | 1 |
| Santa Maria VA Clinic, VA Greater Los Angeles Healthcare System | Burnout, Burnout Syndrome | 1 |
Active & Upcoming Studies in Santa Maria (2026)
Recruiting trials in Santa Maria grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (34 active studies)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
- Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays · Alliance for Clinical Trials in Oncology
Diabetes & metabolic (5 active studies)
- A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities · Phase 2 · Verdiva Bio Dev Limited
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Cardiovascular (5 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) · Phase 1 · Vasa Therapeutics
Common conditions studied in Santa Maria
- Anatomic Stage I Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (3 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Melanoma (3 active studies). Melanoma trials test immune checkpoint inhibitors, adoptive cell therapies, and BRAF/MEK targeted combinations in both early and metastatic disease.
- Stage IIIB Lung Cancer AJCC v8 (3 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Anatomic Stage IV Breast Cancer AJCC v8 (2 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Santa Maria
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- ECOG-ACRIN Cancer Research Group
- National Cancer Institute (NCI)
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Santa Maria. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Santa Maria
Hipa.ai aggregates every recruiting study in Santa Maria from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Santa Maria?
There are approximately 55 recruiting clinical trials in Santa Maria, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Santa Maria pay participants?
Most recruiting trials in Santa Maria compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Santa Maria?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Santa Maria?
The most common conditions under active study in Santa Maria include Anatomic Stage I Breast Cancer AJCC v8 (3), Anatomic Stage II Breast Cancer AJCC v8 (3), Heart Failure (3), Melanoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Santa Maria?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Santa Maria on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Santa Maria?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Santa Maria?
Recruiting research sites in Santa Maria include Mission Hope Medical Oncology - Santa Maria, FOMAT Medical Research, GSK Investigational Site, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Santa Maria right now?
The largest active categories in Santa Maria are Cancer & tumors (34), Diabetes & metabolic (5), Cardiovascular (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.