Clinical Trials at Baystate Medical Center
As of August 2026, 37 paid clinical trials are recruiting at Baystate Medical Center, located at 759 CHESTNUT ST, SPRINGFIELD, MA 01199-1001, phone (413) 794-0000 in Springfield, Massachusetts. Active studies at this site cover conditions such as Alzheimer Disease, Coronary Artery Disease and Opioid Use Disorder. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
Newly added in Springfield
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
38 clinical trials at Baystate Medical Center
·Clear filters·MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
SELUTION 4 De Novo Small Vessel IDE Trial
Pompe Disease Registry Protocol
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
Fabry Disease Registry & Pregnancy Sub-registry
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Project: Every Child for Younger Patients With Cancer
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
A Type I Hybrid Effectiveness-Implementation Trial of MIO
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
Telerehabilitation In The Home After Stroke
Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Skilled Nursing Facility at Home Trial
Effect of Support for Low-Income Mothers of Preterm Infants
Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms
Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study
Groningen International Study on Sentinel Nodes in Vulvar Cancer-III
Aim 2 - Conversations Can Save Lives: TALKing About Buprenorphine & Methadone for Opioid Use Treatment Initiation
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
Common conditions studied in Springfield
- Alzheimer Disease (3 active studies)
- Coronary Artery Disease (3 active studies)
- Opioid Use Disorder (3 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (2 active studies)
- Geographic Atrophy (GA) (2 active studies)
- Heart Diseases (2 active studies)
Leading research sponsors in Springfield
- Baystate Medical Center
- Children's Oncology Group
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Springfield?
There are approximately 74 recruiting clinical trials in Springfield, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Springfield pay participants?
Most recruiting trials in Springfield compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Springfield?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Springfield?
The most common conditions under active study in Springfield include Alzheimer Disease (3), Coronary Artery Disease (3), Opioid Use Disorder (3), Anatomic Stage II Breast Cancer AJCC v8 (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Springfield?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Springfield on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Springfield?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Springfield?
Recruiting research sites in Springfield include Baystate Medical Center, Baystate Health, Elixia MA, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Springfield right now?
The largest active categories in Springfield are Cancer & tumors (23), Mental health & behavior (10), Neurology & pain (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Baystate Medical Center?
Baystate Medical Center is located at 759 CHESTNUT ST, SPRINGFIELD, MA 01199-1001. Use the Google Maps link in the intro above to get directions.
How do I contact Baystate Medical Center?
You can reach Baystate Medical Center by phone at (413) 794-0000. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.