COVID-19 / long COVID Clinical Trials in Worcester, MA
Worcester, Massachusetts hosts paid clinical trials for COVID-19 / long COVID when studies are open for enrollment. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Worcester
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Newly added in Worcester
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
1 clinical trial for COVID-19 / long COVID
·Clear filters·Top Research Study Locations in Worcester
Researchers run research studies in Worcester, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Massachusetts Chan Medical School | Immune Thrombocytopenic Purpura (ITP), Rheumatoid Arthritis, Acute Stress Reaction | 28 |
| UMass Memorial Medical Center - University Campus | Stage IV Lung Cancer AJCC v8, B Acute Lymphoblastic Leukemia, Lung Non-Small Cell Carcinoma | 27 |
| UMass Memorial Medical Center | Intracerebral Hemorrhage, Acute Kidney Injury, Atrial Fibrillation | 20 |
| UMass Chan Medical School | Atrial Fibrillation, AML With Mutated NPM1, ASCVD | 16 |
| University of Massachusetts Memorial Medical Center | Pregnancy, High Risk, B-cell Malignancy, Becker Muscular Dystrophy | 14 |
| University of Massachusetts | Abdominal Aortic Aneurysm, Acute Ischemic Stroke, Acute Myeloid Leukemia (AML) | 11 |
| University of Massachusetts Medical School | Neoplasm Metastasis, Alcohol; Use, Problem, Amyotrophic Lateral Sclerosis | 9 |
| Vitalix Clinical | Major Depressive Disorder, Alzheimer's Disease, Post Traumatic Stress Disorder | 4 |
| UMass Memorial Health | Clostridium Difficile Infection, Fecal Microbiota Transplantation, Fragile X Syndrome | 3 |
| University of Massachusetts Medical Center | Aortic Valve Disease, Aortic Valve Stenosis, COACH | 3 |
| GSK Investigational Site | Multiple Myeloma, Neoplasms, Head and Neck, Newly Diagnosed Multiple Myeloma | 2 |
| Local Institution - 0059 | Schizophrenia, Autism-Related Irritability | 2 |
| Reliant Medical Group | Asthma, Asthma Attack, Asthma Exacerbations | 2 |
| UMass/Shields | Esophageal Cancer, Gastric Cancer (GC), Gastroesophageal Junction | 2 |
| UMassMemorial Health Care | Fatigue, Shift Work Type Circadian Rhythm Sleep Disorder, Wellness, Psychological | 2 |
| University of Massachusetts Memorial Health | Lupus Nephritis, Neuropsychiatric Systemic Lupus Erythematosus, Postpartum Hypertension | 2 |
| University of Massachusetts Memorial Health Care | Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation | 2 |
| Central Massachusetts Health Center | Alcohol-Related Disorders, Contraception, Maternal Health | 1 |
| Clinical Research | Immunoglobulin A Nephropathy | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Decentralized | Adherence, Medication, Anticoagulants and Bleeding Disorders, Atrial Fibrillation | 1 |
| Family Health Center of Worcester | Depression, Diabetes, Hyperlipidemias | 1 |
| Local Institution - 0084 | Systemic Sclerosis | 1 |
| Local Institution - 2615 | Agitation, Alzheimer Disease | 1 |
| MCPHS 10 Lincoln Square | Age-Related Macular Degeneration | 1 |
Active & Upcoming Studies in Worcester (2026)
Recruiting trials in Worcester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (51 active studies)
- Facilitation of Information eXchange for Shared Decision Making for Lung Cancer Screening · University of Massachusetts, Worcester
- Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 · Phase 3 · AstraZeneca
Neurology & pain (15 active studies)
- Social Media and Risk-reduction Training for Preterm Infant Care Practices · University of Massachusetts, Worcester
- Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts · University of Massachusetts, Worcester
Mental health & behavior (13 active studies)
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Cardiovascular (10 active studies)
- Social Needs Screening and Chronic Diseases Study (WE CARE) · University of Massachusetts, Worcester
- ELEVATE High-Risk PCI Pivotal Study · Magenta Medical Ltd.
Diabetes & metabolic (7 active studies)
- Food is Medicine in Pediatric Patients With Diabetes · University of Massachusetts, Worcester
- Re-Engineered Discharge for Diabetes Care Transitions · University of Massachusetts, Worcester
Vaccines (5 active studies)
- Patient-Centered Practical Vaccine Talk For Busy Clinicians · University of Massachusetts, Worcester
- A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine · Phase 3 · Pfizer
Eye & vision (4 active studies)
- CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
- The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma · EARLY_Phase 1 · MCPHS University
Pediatric (4 active studies)
- Social Media and Risk-reduction Training for Preterm Infant Care Practices · University of Massachusetts, Worcester
- Social Needs Screening and Chronic Diseases Study (WE CARE) · University of Massachusetts, Worcester
HIV / STI (1 active study)
Common conditions studied in Worcester
- Schizophrenia (5 active studies)
- Major Depressive Disorder (4 active studies)
- Stage IV Lung Cancer AJCC v8 (4 active studies)
- Acute Myeloid Leukemia (3 active studies)
- Atrial Fibrillation (3 active studies)
- B Acute Lymphoblastic Leukemia (3 active studies)
Leading research sponsors in Worcester
- University of Massachusetts, Worcester
- National Cancer Institute (NCI)
- Children's Oncology Group
- Eli Lilly and Company
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in Worcester?
There are approximately 202 recruiting clinical trials in Worcester, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Worcester pay participants?
Most recruiting trials in Worcester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Worcester?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Worcester?
The most common conditions under active study in Worcester include Schizophrenia (5), Major Depressive Disorder (4), Stage IV Lung Cancer AJCC v8 (4), Acute Myeloid Leukemia (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Worcester?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Worcester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Worcester?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Worcester?
Recruiting research sites in Worcester include University of Massachusetts Chan Medical School, UMass Memorial Medical Center - University Campus, UMass Memorial Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Worcester right now?
The largest active categories in Worcester are Cancer & tumors (51), Neurology & pain (15), Mental health & behavior (13). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.