Autoimmune diseases (general) Clinical Trials

Recruiting autoimmune diseases (general) studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat autoimmune diseases (general). Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting autoimmune diseases (general) studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting autoimmune diseases (general) trials

Within

RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune Diseases

for Autoimmune Diseases

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 5 - 20

Code: NCT07674147·EARLY_Phase 1

Deciphering the Genetic Architecture of Autoimmune Diseases

for Autoimmune Diseases

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 18 - 115

Code: NCT06948110

Apply to this trial

Study of S-4321 in Participants With an Autoimmune or Immune-mediated Disease

for Autoimmune Diseases

Sponsor: Seismic Therapeutic AU Pty Ltd

Sex: All·Age: 18 - 75

Code: NCT07455578·Phase 1

Apply to this trial

Proof of Concept Study Evaluating the Efficacy and Safety of ATH-063 Treatment in Patients With Relapsed/Refractory Moderately to Severely Active Ulcerative Colitis (UC)

for Ulcerative Colitis

2 sites incl. Miami

Sponsor: Athos Therapeutics Inc

Sex: All·Age: 18 - 75

Code: NCT07513181·Phase 2

METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)

for Type 1 Diabetes (T1D)

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 18 - 69

Code: NCT07699380·Phase 2

Apply to this trial

CAR-T Cells Targeting Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 18 - 75

Code: NCT05459870·Phase 1, Phase 2

Apply to this trial

Safety and Efficacy of KSVCBD Injection in Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18 - 65

Code: NCT07613411·EARLY_Phase 1

CD19/BCMA UCAR-T for B Cell-Related Autoimmune Disease

for Autoimmune Diseases

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 3+

Code: NCT07586267·EARLY_Phase 1

Apply to this trial

Clonal Hematopoiesis of Immunological Significance

for Immune System Diseases

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT05969821

Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease

for Autoimmune Diseases

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 3+

Code: NCT07507201·EARLY_Phase 1

Apply to this trial

Cluster of Differentiation 19 (CD19)/B Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor T-Cell (CAR-T) Therapy for Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Shenzhen Genocury Biotech Co., Ltd.

Sex: All·Age: 18 - 70

Code: NCT07490951

Integrating Vaccination Into Hospital Care Pathways for Vulnerable Patients

for Chronic Disease

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18+

Code: NCT07391046

Exploratory Study on LNP-mRNA Drugs Targeting CD19/BCMA for the Treatment of Relapsed and Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: West China Hospital

Sex: All·Age: 18 - 70

Code: NCT07388212·EARLY_Phase 1

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Changhai Hospital

Sex: All·Age: 18 - 70

Code: NCT07246096·EARLY_Phase 1

Apply to this trial

Clinical Study of AFN50 Injection in the Autoimmune Diseases

for Autoimmune Diseases

Sponsor: AlphaNa Bioscience Company Limited

Sex: All·Age: 18 - 69

Code: NCT07408336·EARLY_Phase 1

Apply to this trial

To Evaluate the Safety and Tolerability of STR-P004 for the Treatment of Immune-mediated Kidney Diseases

for Autoimmune Diseases

Sponsor: Starna Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07363954

Exploratory Study on the Treatment of Relapsed and Refractory Immune Related Diseases With WGb-0301 Injection

for Autoimmune Diseases

Sponsor: West China Hospital

Sex: All·Age: 18 - 70

Code: NCT07349823·EARLY_Phase 1

Exploratory Study on mRNA Therapy Targeting CD19 for the Treatment of Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Xinqiao Hospital of Chongqing

Sex: All·Age: 14 - 70

Code: NCT07362758·EARLY_Phase 1

Exploratory Clinical Study of Second-generation CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in Treating Paediatric B Cell-related Autoimmune Diseases

for Paediatric B Cell-related Autoimmune Diseases

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 3+

Code: NCT07283315·EARLY_Phase 1

Apply to this trial

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease

for Autoimmune Diseases

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 3+

Code: NCT07305116·Phase 1

Apply to this trial

Electromagnetic Immunotherapy Mapping and Cytokine Forecasting Study (QSIT)

for Systemic Lupus Erythematosus

1 site in New York

Sponsor: Truway Health, Inc.

Sex: All·Age: All ages

Code: NCT07221565·Phase 1, Phase 2

Natural History of Type 1 Interferonopathies: Insights From a European Cohort

for Genetic Disease

Sponsor: Imagine Institute

Sex: All·Age: All ages

Code: NCT07040774

Apply to this trial

A Study of CAR-T Cells in Subjects With Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18 - 65

Code: NCT07040917·EARLY_Phase 1

Inectolizumab With Steroid Optimization in Newly Treated NMOSD

for Neuromyelitis Optica

Sponsor: First Affiliated Hospital of Wenzhou Medical University

Sex: All·Age: 18 - 65

Code: NCT07159893

Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Hebei Senlang Biotechnology Inc., Ltd.

Sex: All·Age: 18 - 70

Code: NCT07161193·Phase 1, Phase 2

Exploratory Clinical Study on the Safety of STR-P004

for Autoimmune Diseases

Sponsor: Beijing GoBroad Hospital

Sex: All·Age: 18+

Code: NCT07143617

Apply to this trial

Anti CD19/BCMA CAR Gene Therapy for Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Anhui Provincial Hospital

Sex: All·Age: 18+

Code: NCT07121777

Apply to this trial

GT719 Injection for Moderate to Severe Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Grit Biotechnology

Sex: All·Age: 18 - 65

Code: NCT07122076·EARLY_Phase 1

Apply to this trial

CAR-T Therapy for Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: LiangZou

Sex: All·Age: 18+

Code: NCT07059169

Apply to this trial

CAR-T Cells Therapy for Patients With Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Anhui Provincial Hospital

Sex: All·Age: 18+

Code: NCT07052565

Apply to this trial

Single-cell Immune Response to Controlled Gluten Ingestion in Pediatric Celiac Disease

for Celiac Disease

Sponsor: Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud

Sex: All·Age: 8 - 14

Code: NCT07362654

Apply to this trial

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

for Diabetes Mellitus, Type 1

1 site in Chicago

Sponsor: Otsuka Pharmaceutical Factory, Inc.

Sex: All·Age: 35 - 65

Code: NCT06575426·Phase 1, Phase 2

Apply to this trial

The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology.

for Migraine Disorders

Sponsor: University Hospital, Clermont-Ferrand

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06426316

Apply to this trial

Network to Understand Reproductive Rheumatology Registry

for Rheumatic Diseases

1 site in Durham

Sponsor: Duke University

Sex: Female·Age: 12 - 55

Code: NCT06940869

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

13 sites incl. Los Angeles

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1

Apply to this trial

An Observational Study of Patients With Autoimmune Disease

for Autoimmune Diseases

Sponsor: Target PharmaSolutions, Inc.

Sex: All·Age: 18+

Code: NCT05842824

JY231(JY231) Injection for the Treatment of Refractory Autoimmune Diseases (ADs)

for Autoimmune Diseases

Sponsor: He Huang

Sex: All·Age: 18 - 75

Code: NCT06887985

Efficacy and Safety of Efgartigimod Sequential Therapy with Telitacicept in Generalized Myasthenia Gravis

for Myasthenia Gravis

Sponsor: First Affiliated Hospital of Wenzhou Medical University

Sex: All·Age: 18 - 80

Code: NCT06827587

Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases

for Systemic Lupus

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 1+·Accepts healthy volunteers

Code: NCT06435468

Apply to this trial

Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease

for Autoimmune Diseases

1 site in Nashville

Sponsor: Toyos Clinic

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06964269·Phase 4

Apply to this trial

Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune Disease

for Autoimmune Diseases

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 3+

Code: NCT06792799·EARLY_Phase 1

Apply to this trial

Prospective Observational Study Evaluating the Safety and Efficacy of Immunomodulatory Therapies in Refractory Inflammatory and Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Groupe français d'étude des Maladies Inflammatoires de loeil

Sex: All·Age: 18+

Code: NCT06757426

A Study of CAR-T Cells in Subjects with Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Zhejiang University

Sex: All·Age: 18 - 65

Code: NCT06762119·EARLY_Phase 1

Telitacicept and Low-dose Steroids in Refractory Myasthenia Gravis

for Myasthenia Gravis

Sponsor: First Affiliated Hospital of Wenzhou Medical University

Sex: All·Age: 18 - 85

Code: NCT06723548·Phase 4

A Study of mRNA Encoding CD19/CD3 T Cell Engager (ABO2203) in Patients With Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Ruijin Hospital

Sex: All·Age: 18+

Code: NCT06747156·EARLY_Phase 1

Apply to this trial

Testimonials and Navigation in Rheumatology

for Rheumatologic Disease

3 sites incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT06469788

Apply to this trial

Phase 1 Clinical Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP212525 in Healthy Volunteers

for Autoimmune Diseases

Sponsor: Daewoong Pharmaceutical Co. LTD.

Sex: All·Age: 19 - 55·Accepts healthy volunteers

Code: NCT06736587·Phase 1

Apply to this trial

Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center

for Thrombotic Thrombocytopenic Purpura (TTP)

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: All ages

Code: NCT07205861

Apply to this trial

Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Beijing GoBroad Hospital

Sex: All·Age: 3 - 65

Code: NCT06688799·Phase 1, Phase 2

Apply to this trial

Research of Predictive Factors of in Vitro Fertilization (IVF) Outcome AI-IVF Study

for Autoimmune Diseases

Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia

Sex: Female·Age: 18 - 43

Code: NCT06872294

Apply to this trial

A Study of CAR-T Cells Targeting Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Beijing Boren Hospital

Sex: All·Age: 18 - 65

Code: NCT06661811

CD19 CAR-T in the Treatment of Relapsed/Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Institute of Hematology & Blood Diseases Hospital, China

Sex: All·Age: 18 - 65

Code: NCT06680388·EARLY_Phase 1

Apply to this trial

A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease

for Lupus Nephritis

2 sites incl. Redwood City

Sponsor: Adicet Therapeutics

Sex: All·Age: 18 - 80

Code: NCT06375993·Phase 1

Digital Diagnostics and Intervention Services for Parkinson's Disease

for Brain Diseases

Sponsor: University of Exeter

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06534177

Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care

for Diabetes Mellitus

Sponsor: Anne-Sophie Brazeau

Sex: All·Age: 14 - 16

Code: NCT05910840

Apply to this trial

JWCAR201 for the Treatment of Hematology Malignancy and Autoimmune Diseases

for B-cell Tumors

Sponsor: RenJi Hospital

Sex: All·Age: 18 - 70

Code: NCT06567080·Phase 1

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

for SLE (Systemic Lupus)

Sponsor: Nanjing Bioheng Biotech Co., Ltd.

Sex: All·Age: 18 - 70

Code: NCT06548607·EARLY_Phase 1

Apply to this trial

Cancer as a complicATion in reCipients of Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Disease iNdiCation trEated in FRance and Canada?

for Autoimmune Diseases

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT06507800

Risk and Clinical Consequences of Low Count Monoclonal B-cell Lymphocytosis (LC MBL)

for Monoclonal B-Cell Lymphocytosis

Sponsor: University of Haifa

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT06416267

Biomarkers in Autoimmune Disease of Nervous System

for Autoimmune Diseases of the Nervous System

Sponsor: Tongji Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06502015

Apply to this trial

Autoimmune diseases (general) clinical trials — common questions

Are autoimmune diseases (general) clinical trials free to join?

Yes. Participating in a autoimmune diseases (general) clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a autoimmune diseases (general) clinical trial?

Each autoimmune diseases (general) study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a autoimmune diseases (general) trial near me?

Use the location controls above. We'll show recruiting autoimmune diseases (general) trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many autoimmune diseases (general) trials are recruiting right now?

We're currently tracking roughly 23 recruiting autoimmune diseases (general) trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Autoimmune diseases (general) trials by city

Birmingham, AL Chicago, IL Columbus, OH Huntsville, AL Los Angeles, CA Miami, FL Orange, CA Orlando, FL Redwood City, CA Seattle, WA

Related specialties

Rheumatology Autoimmune disease