Cannabis use / cannabis use disorder Clinical Trials

Recruiting cannabis use / cannabis use disorder studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat cannabis use / cannabis use disorder. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting cannabis use / cannabis use disorder studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting cannabis use / cannabis use disorder trials

Within

Transcranial Magnetic Stimulation for Adolescents and Young Adults With Cannabis Use Disorder

for Cannabis Use

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 15 - 21

Code: NCT07634835

Trial of Tirzepatide for the Treatment of Cannabis Use Disorder

for Cannabis Use Disorder

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 18 - 70

Code: NCT07468552·Phase 2

Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples

for Alcohol Drinking

Sponsor: University of Washington

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT06422299

Smart Talk: Cannabis Awareness and Prevention Curriculum Evaluation

for Cannabis Use

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 10 - 20·Accepts healthy volunteers

Code: NCT07357454

Pregnenolone for Cannabis Use Disorder and Depression

for Cannabis Use Disorder

2 sites incl. Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 50

Code: NCT07685964·Phase 1, Phase 2

Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis

for Cannabis Use

1 site in Lexington

Sponsor: Hannah Harris

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07694466·EARLY_Phase 1

Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study

for Cannabis Use Disorder

1 site in San Bernardino

Sponsor: Loma Linda University

Sex: All·Age: 18+

Code: NCT07001371

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

for Cannabis Use

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06351540·Phase 1

Behavioral Pharmacology of THC and Beta-Myrcene

for Cannabis Use

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT05432284·Phase 1

Acute Effects of Cannabis on Cognition and Affect

for Cannabis Use

1 site in Pullman

Sponsor: Washington State University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07296874·Phase 2

Cannabis and Opioid Use Disorder, Study 2

for Opioid Use Disorders

1 site in Lexington

Sponsor: University of Kentucky

Sex: All·Age: 18 - 55

Code: NCT07661446·Phase 1

Cannabis Effects on Opioid Self-Administration

for Opioid Use Disorder

1 site in Lexington

Sponsor: Shanna Babalonis, PhD

Sex: All·Age: 18 - 55

Code: NCT07668635·Phase 1

Research Investigating Drug Effects-2 (RiDE-2)

for Cannabis Use

1 site in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18 - 21·Accepts healthy volunteers

Code: NCT06758596·EARLY_Phase 1

Brief Family-Based Cannabis Use Intervention for Youth With Early Juvenile Justice Involvement

for Cannabis Use

1 site in Providence

Sponsor: Rhode Island Hospital

Sex: All·Age: 12 - 16

Code: NCT07700849

Tirzepatide for the Treatment of Cannabis Use Disorder

for Cannabis Use Disorder

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07265752·Phase 2

Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum

for Perinatal

1 site in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18+

Code: NCT07489443

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Neuroimaging of Adolescent Cannabis Use Treatment

for Cannabis Use

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 14 - 17

Code: NCT07340554

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Perceptions of Proposed Warnings for Cannabis Edibles Packaging

for Cannabis Use

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07496489

Testing Warning Labels for Retail Cannabis Products Using a Discrete Choice Experiment

for Cannabis Use

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 21+

Code: NCT07701304

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Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder

for Cannabis Use Disorder

Sponsor: Anders Fink-Jensen, MD, DMSci

Sex: All·Age: 18 - 70

Code: NCT07523633·Phase 2

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Joint Effort 2.0 : Evaluation Among General Population

for Cannabis Use

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07524985

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Sex Differences in Neurobehavioral Response to THC

for Cannabis Use Disorder

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21 - 45

Code: NCT07225777·Phase 2

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Evaluating the Impact of Psychotherapeutic Advertising Claims on Cannabis Purchasing

for Anxiety

1 site in Lebanon

Sponsor: Trustees of Dartmouth College

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07216911

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Effects of Cannabis Species Labeling and Marketing on Perceptual, Subjective and Objective Use Outcomes (Aim 2 Study)

for Cannabis Use

1 site in Baltimore

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07513337

Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis

for Psychosis

Sponsor: Nova Scotia Health Authority

Sex: All·Age: 16 - 30

Code: NCT07056894

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Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Use

for Methamphetamine Induced Psychosis

Sponsor: Elazığ Mental Health and Diseases Hospital

Sex: Male·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07459270

Cannabis Reduction and Functional Outcomes

for Cannabis Use Disorder

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07218471

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Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

for Depression - Major Depressive Disorder

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06878859

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A Brief Cannabis Use Psychoeducation Intervention for Eating Disorder Patients

for Eating Disorders

Sponsor: St. Joseph's Healthcare Hamilton

Sex: All·Age: 16+

Code: NCT07387965

Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia

for Cannabis Use

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07196462

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Impact of Cannabis Use During Third Molar Surgery

for Cannabis Use

1 site in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 16 - 99

Code: NCT07423195

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Testing the Effects of Cann'App, a Digital Intervention for Cannabis Harm Reduction

for Cannabis Use

Sponsor: Jacques Gaume

Sex: All·Age: 18+

Code: NCT07157540

Investigating Cannabis Use Parameters on Anesthesia and Inflammation in Lumbar Spinal Surgeries

for Cannabis Use

2 sites in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07354412

THC + CBD and Memory Study

for Marijuana Use

Sponsor: Hartford Hospital

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT04855526·EARLY_Phase 1

Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis (CCP) Intervention for Cannabis Use Reduction/Cessation in Patients With First Episode Psychosis (FEP)

for Psychosis

Sponsor: King's College London

Sex: All·Age: 18 - 65

Code: NCT07245212

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

for Cannabis Use Disorder

1 site in New York

Sponsor: NYU Langone Health

Sex: All·Age: 22 - 65

Code: NCT07184983

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Skills for Talking About Cannabis for Families of Young Adults With Psychosis

for Caregiver Burden

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06961877

Study of an Oral Fluid Testing Approach

for Cannabis Use

1 site in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 30

Code: NCT06891235

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Warrior CARE: Cannabis Behavioral Health

for Post Traumatic Stress Disorder

1 site in Detroit

Sponsor: Wayne State University

Sex: All·Age: 19 - 69

Code: NCT06381180·Phase 1, Phase 2

Cannabis Use Patterns Among Young Adults and Associations With Social and Health Outcomes.

for Cannabis Use

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT07063589

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Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

for Cannabis Use

1 site in Saint Louis Park

Sponsor: HealthPartners Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07227324

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Exercise Intervention as Treatment for People Using Cannabis (ExIT-C)

for Cannabis Abuse

Sponsor: The University of Hong Kong

Sex: All·Age: 18 - 40

Code: NCT07091292

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Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

for THC

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT05999383·Phase 2

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Cannabis-Tobacco Co-Use Treatment Study

for Tobacco Use Disorder

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06883162·Phase 3

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Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

for Adolescent Drinking

2 sites incl. Commerce

Sponsor: RAND

Sex: All·Age: 12 - 19·Accepts healthy volunteers

Code: NCT06699251

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Effect of Cannabis on E-Cigarette Use Behavior

for Cannabis Use

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06609109·Phase 1

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Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis

for Psychosis

Sponsor: Nova Scotia Health Authority

Sex: All·Age: 18 - 25

Code: NCT07001878·Phase 4

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Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults

for Cannabis Use

1 site in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT06743373

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Neural and Psychiatric Consequences of Cannabis Use in Adolescents

for Cannabis Use

2 sites incl. Miami

Sponsor: University of Miami

Sex: All·Age: 14 - 20·Accepts healthy volunteers

Code: NCT06941298

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Cannabis, Linked Emotions, and Adolescent Risk Study

for Cannabis Use

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12 - 18

Code: NCT06576076

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Perceptual Influences From Smoking Cannabis: an Experimental Study

for Cannabis Use

1 site in Boulder

Sponsor: University of Colorado, Boulder

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT06588582

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Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care

for Substance Use

Sponsor: Prof. Dagmar M. Haller

Sex: All·Age: 14 - 24·Accepts healthy volunteers

Code: NCT04146714

Effect of Cannabis on Cigarette Use Behavior

for Cannabis Use

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06609083·Phase 1

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Stress and Pain in People Living With HIV

for HIV

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 68·Accepts healthy volunteers

Code: NCT06784908

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HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

for Hiv

1 site in West Haven

Sponsor: Yale University

Sex: All·Age: 50+

Code: NCT06513819·Phase 1

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Developing a Telehealth + mHealth Cannabis Use Intervention for Young Adults

for Cannabis Use Disorder

1 site in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 26

Code: NCT06661031

A Study of Cannabidiol in Young Adult Cannabis Users

for Cannabis Use Disorder

1 site in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 25

Code: NCT06569394·Phase 2

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Cannabidiol and Cannabis Concentrate Users

for Cannabis Use Disorder

1 site in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 25 - 60

Code: NCT06575751·Phase 2

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Integrated Treatment for Enhancing Growth in Recovery During Adolescence

for Alcohol Use Disorder

2 sites incl. Farmington

Sponsor: Massachusetts General Hospital

Sex: All·Age: 14 - 21

Code: NCT06395467

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Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development

for Child Development

1 site in Aurora

Sponsor: University of Colorado, Denver

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06379971·Phase 1

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Cannabis use / cannabis use disorder clinical trials — common questions

Are cannabis use / cannabis use disorder clinical trials free to join?

Yes. Participating in a cannabis use / cannabis use disorder clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a cannabis use / cannabis use disorder clinical trial?

Each cannabis use / cannabis use disorder study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a cannabis use / cannabis use disorder trial near me?

Use the location controls above. We'll show recruiting cannabis use / cannabis use disorder trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many cannabis use / cannabis use disorder trials are recruiting right now?

We're currently tracking roughly 68 recruiting cannabis use / cannabis use disorder trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Cannabis use / cannabis use disorder trials by city

Aurora, CO Boston, MA Boulder, CO Miami, FL Tallahassee, FL Ann Arbor, MI Chicago, IL Detroit, MI Fort Collins, CO Indianapolis, IN Oklahoma City, OK Palo Alto, CA

Related specialties

Behavioral health Addiction medicine