Dementia Clinical Trials

Recruiting dementia studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat dementia. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting dementia studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting dementia trials

Within

Hearing Loss and Brain Health Study

for Hearing Loss, Adult-Onset

1 site in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 50+

Code: NCT07288463

Concurrent Trials on Nature-Based Therapy for Inpatients in Dementia and Rehabilitation Medicine Wards

for Dementia

Sponsor: Changi General Hospital

Sex: All·Age: 21 - 100

Code: NCT07059390

ED PLWD/Care Partner Text Messaging

for Dementia

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07423871

Adapting Changing Talk: Online (CHATO) to CHATO-Inclusive

for Dementia

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06636214

Feasibility of A Smartphone Application Intervention in Community Settings: A Pretest-Posttest Pilot Study

for Aging

1 site in Galveston

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT07313540

The Care for America's Aging Study

for Cognitive Impairment

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06021704

Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables

for Active Aging Individuals Aged 65 and Over

Sponsor: Neuromed IRCCS

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07533084

Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)

for Elder Mistreatment

1 site in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07216950

Using Community Health Workers to Support Rural Care Partners of Seriously Ill Older Veterans

for Dementia

1 site in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06963970

Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention

for MCI

Sponsor: Alexandra Hospital

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT07612800

NMDA Enhancement Combined With Omega-3 for Early Dementia

for Omega 3 Fatty Acids

Sponsor: Chang Gung Memorial Hospital

Sex: All·Age: 50 - 100

Code: NCT05181189·Phase 2

Prediction and Prevention of Postoperative Mortality and Morbidity

for Dementia

5 sites in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 65+

Code: NCT06042413

A Study Of Phototherapy In Patients With Dementia To Improve BPSD

for Dementia

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07488195

Support in Sound: Music Therapy for People Living With Dementia and Companions in Rural Communities

for Dementia

Sponsor: Anglia Ruskin University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07693114

An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)

for Mild Cognitive Impairment (MCI)

1 site in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07127133

Cholinergic Deep Brain Stimulation for Alzheimer's Disease

for Alzheimer Disease, Early Onset

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60 - 80

Code: NCT05882344

Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease

for Alzheimer Disease

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06045988

Cooking Health-Oriented Meals to Prevent Dementia and Diabetes

for Type 2 Diabetes

Sponsor: Virginia Polytechnic Institute and State University

Sex: All·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07661368

Neuromodulation for Behavioral Changes in Neurological Disorders

for Dementia

1 site in Morgantown

Sponsor: West Virginia University

Sex: All·Age: 45 - 80

Code: NCT07718906

Low-Dose Radiotherapy for Alzheimer's Disease

for Alzheimer Dementia

1 site in Winter Park

Sponsor: Evan Thomas

Sex: All·Age: 50+

Code: NCT07693140·Phase 1, Phase 2

Apply to this trial

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

for Diabetes

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 65+

Code: NCT05643144

Apply to this trial

Web-Based Psychoeducation for Dementia Caregivers

for Dementia

Sponsor: Lotung Poh-Ai Hospital

Sex: All·Age: 20 - 90

Code: NCT07690280

Apply to this trial

Brain Wave Informed Non-invasive Brain Stimulation: Improving Neural Networks of Working Memory in Dementia: a Proof-of-concept Study

for Dementia

Sponsor: McMaster University

Sex: All·Age: 55+

Code: NCT07673770

Apply to this trial

Penn State Emergency Medicine CarES: Care-partner Evaluation and Sourcing in the Emergency Department

for Dementia

1 site in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 60+

Code: NCT07461168

The WeACT Program for Family Caregivers of People Living With Dementia

for Depression

1 site in Tampa

Sponsor: University of South Florida

Sex: All·Age: 18+

Code: NCT07342569

Dementia Management Training Programme for Primary Health Care Providers

for Dementia

Sponsor: Fujian Medical University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07617883

Music for Pain and Dementia

for Alzheimer Disease

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT07602283

Apply to this trial

Virtual Reality Intervention for Family Caregivers of Persons Living With Dementia

for Dementia

Sponsor: Chang Gung Memorial Hospital

Sex: All·Age: 18 - 120

Code: NCT07248345

CommunityRx-Dementia + Peer Navigation (CRxDpeer)

for Alzheimer s Disease

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07346183

Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

for Osteoarthritis (OA) of the Hip

1 site in Fairway

Sponsor: University of Kansas Medical Center

Sex: All·Age: 55 - 75

Code: NCT07417891

Management of Age-Related Auditory Decline and Early Warning of Its Co-occurring Dementia

for Age-related Hearing Loss

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07608640

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

for Alzheimer Disease

52 sites incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 55+

Code: NCT07602582·Phase 3

Apply to this trial

Effectiveness of a Culturally Adapted Online Education Program (iSupport-Korea) for Family Caregivers of People With Dementia

for Dementia

Sponsor: Chungnam National University

Sex: All·Age: 19+

Code: NCT07609316

Apply to this trial

Preventing Medication Mismanagement in People Living With Dementia

for Dementia

1 site in Folsom

Sponsor: HiDO Technologies

Sex: All·Age: 65+

Code: NCT07600684

Apply to this trial

Improving Dementia Care in Primary Practice

for Alzheimer Disease (AD)

Sponsor: Thomas Jefferson University

Sex: All·Age: 66+·Accepts healthy volunteers

Code: NCT07526480

Acute Hospital Care at Home for People Living With Dementia

for Emergency Department Visit

1 site in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06819852

Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia

for Cardiovascular Disease

Sponsor: Tor Biering-Sørensen

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07485283·Phase 4

Apply to this trial

DIV-AD BARCELONA: Alzheimer's Blood-Based Biomakers for a Diverse Community

for Alzheimer Disease

Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation

Sex: All·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07521722

Human Observatory Study

for Aging

1 site in Boulder

Sponsor: Longevity Metrics, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07646782

Apply to this trial

Tele-Savvy for Latino Caregivers

for Alzheimer Disease

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT07290387

Apply to this trial

e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

for Dementia

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07454824

Apply to this trial

Financial Counseling for Dementia Family Caregivers in Early and Middle Adulthood

for Family Caregivers

1 site in Salt Lake City

Sponsor: University of Utah

Sex: All·Age: 25 - 55·Accepts healthy volunteers

Code: NCT07681401

Apply to this trial

The Impact of Music Intervention on Sleep

for Dementia

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06088810

Apply to this trial

Fostering Positive Care Interactions in Assisted Living

for Dementia

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 55+

Code: NCT07378800

BrainLive Connect: Non-professional Delivered CST for People Living With Dementia

for Dementia

Sponsor: The University of Hong Kong

Sex: All·Age: 18+

Code: NCT07531589

Apply to this trial

NeuroCare Community Project: A Community Based Prospective Observational Study for Early Alzheimer's Detection in HK

for AD - Alzheimer's Disease

Sponsor: Hong Kong University of Science and Technology

Sex: All·Age: 60 - 75·Accepts healthy volunteers

Code: NCT07347574

Apply to this trial

Large Language Model for Understanding and Monitoring Elderly Neurocognition

for Dementia

Sponsor: Northumbria Healthcare NHS Foundation Trust

Sex: All·Age: 65+

Code: NCT07347431

Apply to this trial

Dementia in Fiction and Clinical Narratives

for Dementia

Sponsor: Fu Jen Catholic University

Sex: All·Age: 60 - 85·Accepts healthy volunteers

Code: NCT07482800

Apply to this trial

Salivary Gland Massage and Olfactory Stimulation for Relieving Feeding Difficulty and Triggering Oral Intake Among People With Dementia

for Experimental

Sponsor: National Cheng Kung University

Sex: All·Age: All ages

Code: NCT07678515

The Black Immigrant Project

for Dementia

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07546708

Apply to this trial

AI4HOPE Pilot Study 1 Digital Toolkit Assessment

for Dementia

Sponsor: University of Bonn

Sex: All·Age: All ages

Code: NCT06289322

AI4HOPE Pilot Study 2 Digital Dementia Care Planning

for Dementia

Sponsor: University of Bonn

Sex: All·Age: All ages

Code: NCT06292143

Communication for Early Mobilisation of People Living With Dementia Following Surgery for Hip Fracture

for Dementia

Sponsor: University of Nottingham

Sex: All·Age: 18+

Code: NCT07418268

Multicomponent Exercise Program on Physical Function, Cognition and Falls Risk Among Older Adults Living in Nursing Homes (MOVE4CARE)

for Frailty

Sponsor: Universidade do Porto

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07392944

Apply to this trial

WeCareToFeedDysphagia to Reduce Care-partner Burden Full-scale RCT

for Caregiver Burden

1 site in Manhasset

Sponsor: Northwell Health

Sex: All·Age: 18+

Code: NCT07250113

Clinical Validation of AI-powered Smart Vehicle Assisted Gait Training in Neurodegenerative Disorders

for Parkinson's Disease (PD)

Sponsor: Taipei Medical University Shuang Ho Hospital

Sex: All·Age: 50 - 85

Code: NCT07230366

Dyadic, App-supported Collaborative Care Intervention Trial for Family Caregivers of People Living With Dementia

for Dementia

Sponsor: German Center for Neurodegenerative Diseases (DZNE)

Sex: All·Age: All ages

Code: NCT07251088

Validation of the Montreal Cognitive Assessment (MoCA) Version 8.x and MoCA-MIS in Greece.

for MCI

Sponsor: Aristotle University Of Thessaloniki

Sex: All·Age: 55 - 85·Accepts healthy volunteers

Code: NCT07297121

The Exercogs® Study

for Dementia

Sponsor: Eduarda Oliosi, MS

Sex: All·Age: 55+

Code: NCT07530315

Apply to this trial

Effects of a Social Robot Cognitive-Game Intervention in Older Adults With Mild Cognitive Impairment and Dementia

for Dementia

Sponsor: Taipei Medical University

Sex: All·Age: 50 - 100

Code: NCT07272746

Dementia clinical trials — common questions

Are dementia clinical trials free to join?

Yes. Participating in a dementia clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a dementia clinical trial?

Each dementia study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a dementia trial near me?

Use the location controls above. We'll show recruiting dementia trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many dementia trials are recruiting right now?

We're currently tracking roughly 115 recruiting dementia trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Dementia trials by city

Boston, MA Birmingham, AL Miami, FL Indianapolis, IN Los Angeles, CA San Francisco, CA Boulder, CO Columbus, OH Tampa, FL Aurora, CO Bloomington, IN Chicago, IL

Related specialties

Neurology Dementia care Brain disorders Geriatrics