Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics
for Hemoglobin
1 location in Boston
Sponsor: Boston Children's Hospital
Sex: All·Age: 0 Days - 21
Code: NCT07706140·Not Yet Recruiting·Listed Jul 15, 2026
Heart disease Clinical Trials in Boston, MA
As of August 2026, 97 paid clinical trials are recruiting for Heart disease in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Boston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
98 clinical trials for Heart disease
·Clear filters· Email me when a new heart disease trial opens in Boston, MA.
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
for Cardiovascular Disease
Drug: Olpasiran
Sites in Boston +193 more locations
Sponsor: Amgen
Sex: All·Age: 50 - 105
Code: NCT07136012·Phase 3·Recruiting·Listed Aug 2025
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
for Atrial Fibrillation (AF)
Sites in Boston +41 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT07175428·Phase 2·Recruiting·Listed Sep 2025
Assessment of CCM in HF With Higher Ejection Fraction
for Heart Failure
Sites in Boston +75 more locations
Sponsor: Impulse Dynamics
Sex: All·Age: 18+
Code: NCT05064709·Recruiting·Listed Oct 2021
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
for Hypertension
Sites in Boston +55 more locations
Sponsor: Orchestra BioMed, Inc
Sex: All·Age: 18+
Code: NCT06059638·Recruiting·Listed Sep 2023
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
for Amyloidosis
Drug: Acoramidis
Sites in Boston +39 more locations
Sponsor: Eidos Therapeutics, a BridgeBio company
Sex: All·Age: 18 - 75
Code: NCT06563895·Phase 3·Recruiting·Listed Aug 2024
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
for Heart Failure
Sites in Boston +82 more locations
Sponsor: Cytokinetics
Sex: All·Age: 18 - 85
Code: NCT06736574·Phase 3·Recruiting·Listed Dec 2024
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
for Cardiovascular Diseases
Sites in Boston +46 more locations
Sponsor: BrioHealth Solutions, Inc.
Sex: All·Age: 18 - 100
Code: NCT06310031·Recruiting·Listed Mar 2024
SELUTION 4 De Novo Small Vessel IDE Trial
for Coronary Artery Disease
Sites in Boston, Springfield +62 more locations
Sponsor: M.A. Med Alliance S.A.
Sex: All·Age: 18+
Code: NCT05946629·Recruiting·Listed Jul 2023
Global Paradise System US Post Approval Study
for Hypertension
Sites in Boston +42 more locations
Sponsor: ReCor Medical, Inc.
Sex: All·Age: 18+
Code: NCT06297291·Recruiting·Listed Mar 2024
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
for Heart Failure
Sites in Boston +56 more locations
Sponsor: Abbott Medical Devices
Sex: All·Age: 18+
Code: NCT06526195·Recruiting·Listed Jul 2024
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
for Heart Failure NYHA Class II
Sites in Boston +44 more locations
Sponsor: Endotronix, Inc.
Sex: All·Age: 18+
Code: NCT05934487·Recruiting·Listed Jul 2023
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
for Atrial Fibrillation (AF)
Drug: Abelacimab
Sites in Boston, Fall River +131 more locations
Sponsor: Anthos Therapeutics, Inc.
Sex: All·Age: 65+
Code: NCT05712200·Phase 3·Recruiting·Listed Feb 2023
CCM OPEN HF Registry
for Heart Failure
Sites in Boston +27 more locations
Sponsor: Impulse Dynamics
Sex: All·Age: 18+
Code: NCT07112924·Recruiting·Listed Aug 2025
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
for Functional Mitral Regurgitation
Sites in Boston +50 more locations
Sponsor: Cardiac Dimensions, Inc.
Sex: All·Age: 18+
Code: NCT03142152·Recruiting·Listed May 2017
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
for Atrial Fibrillation
Sites in Boston +38 more locations
Sponsor: Biosense Webster, Inc.
Sex: All·Age: 18 - 80
Code: NCT06455098·Recruiting·Listed Jun 2024
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
for In-Stent Restenosis
Sites in Boston +27 more locations
Sponsor: Concept Medical Inc.
Sex: All·Age: 18 - 110
Code: NCT05908331·Recruiting·Listed Jun 2023
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
for Atherosclerosis
Drug: Lepodisiran
Sites in Boston +16 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 45 - 80
Code: NCT07613294·Phase 3·Recruiting·Listed May 2026
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
for Atrial Fibrillation
Sites in Boston +29 more locations
Sponsor: Biosense Webster, Inc.
Sex: All·Age: 18 - 80
Code: NCT07523750·Recruiting·Listed Apr 2026
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
for Atrial Fibrillation
Sites in Boston +22 more locations
Sponsor: Biosense Webster, Inc.
Sex: All·Age: 18 - 80
Code: NCT07527299·Recruiting·Listed Apr 2026
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
for Atrial Fibrillation (AF)
Sites in Boston +21 more locations
Sponsor: Medtronic Cardiac Ablation Solutions
Sex: All·Age: 18+
Code: NCT07298473·Recruiting·Listed Dec 2025
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
for Heart Failure
Sites in Boston +19 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 29 Days - 17
Code: NCT05714085·Phase 2, Phase 3·Recruiting·Listed Feb 2023
SPYRAL GEMINI Pilot Study
for Hypertension
Sites in Boston +11 more locations
Sponsor: Medtronic Vascular
Sex: All·Age: 18 - 80
Code: NCT06907147·Recruiting·Listed Apr 2025
Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation
for Atrial Fibrillation
Sites in Boston +3 more locations
Sponsor: Javelin Medical
Sex: All·Age: 18+
Code: NCT05723926·Recruiting·Listed Feb 2023
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
for Coronary Artery Disease
Sites in Boston +9 more locations
Sponsor: Teleflex
Sex: All·Age: 18+
Code: NCT06779630·Recruiting·Listed Jan 2025
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
for Congenital Heart Disease
Sites in Boston +7 more locations
Sponsor: Starlight Cardiovascular Inc
Sex: All·Age: 1 Minute - 6 Months
Code: NCT07114718·Recruiting·Listed Aug 2025
Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation
for Hypertension
1 location in Boston
Sponsor: Medtronic Vascular
Sex: All·Age: 18+
Code: NCT07174622·Recruiting·Listed Sep 2025
PKP2-ACM Natural History Study
for Cardiomyopathies
Sites in Boston +1 more location
Sponsor: Rocket Pharmaceuticals Inc.
Sex: All·Age: 12+
Code: NCT06644742·Recruiting·Listed Oct 2024
Lumason® Infusion vs. Bolus Administrations
for Heart Diseases
Sites in Boston +4 more locations
Sponsor: Bracco Diagnostics, Inc
Sex: All·Age: 18+
Code: NCT06400004·Phase 3·Recruiting·Listed May 2024
A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System
for Heart Failure
1 location in Boston
Sponsor: Vectorious Medical Technologies Ltd.
Sex: All·Age: 22 - 88
Code: NCT06147336·Recruiting·Listed Nov 2023
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)
for Coronary Artery Disease
Sites in Boston +16 more locations
Sponsor: Emory University
Sex: All·Age: 18+
Code: NCT07559903·Recruiting·Listed Apr 2026
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
for Cardiovascular Diseases
Sites in Boston +4 more locations
Sponsor: Fundación EPIC
Sex: All·Age: 18 - 85
Code: NCT07286578·Recruiting·Listed Dec 2025
Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia
for Hypertension
2 locations in Boston
Sponsor: Massachusetts General Hospital
Sex: Female·Age: 18 - 65
Code: NCT07238400·Phase 2·Recruiting·Listed Nov 2025
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
for Atrial Fibrillation
Sites in Boston, Burlington +85 more locations
Sponsor: Johns Hopkins University
Sex: All·Age: 22 - 85
Code: NCT05836987·Phase 3·Recruiting·Listed May 2023
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
for Atrial Fibrillation
Sites in Boston +34 more locations
Sponsor: Icahn School of Medicine at Mount Sinai
Sex: All·Age: 18+
Code: NCT04045665·Phase 3·Recruiting·Listed Aug 2019
EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)
for Heart Failure With Preserved Ejection Fraction
1 location in Boston
Sponsor: Massachusetts General Hospital
Sex: All·Age: 40+
Code: NCT07202000·Phase 2·Recruiting·Listed Oct 2025
Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AF
for Atrial Fibrillation
Sites in Boston +4 more locations
Sponsor: Massachusetts General Hospital
Sex: All·Age: 18 - 80
Code: NCT06099730·Recruiting·Listed Oct 2023
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
for Cognitive Impairment, Mild
Sites in Boston +90 more locations
Sponsor: Duke University
Sex: All·Age: 75+·Accepts healthy volunteers
Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020
CTSN Embolic Protection Trial
for Delirium
Sites in Boston +18 more locations
Sponsor: Icahn School of Medicine at Mount Sinai
Sex: All·Age: 60+
Code: NCT06027788·Recruiting·Listed Sep 2023
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
for Intracerebral Hemorrhage
Sites in Boston, Burlington +140 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019
Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
for Hypertension
1 location in Boston
Sponsor: Massachusetts General Hospital
Sex: Female·Age: 18+
Code: NCT06557005·Recruiting·Listed Aug 2024
Top Research Study Locations in Boston
Researchers run research studies in Boston, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Massachusetts General Hospital | Breast Cancer, Advanced Solid Tumor, Heart Failure | 694 |
| Brigham and Women's Hospital | Obesity, Breast Cancer, Prostate Cancer | 350 |
| Dana-Farber Cancer Institute | Breast Cancer, Acute Myeloid Leukemia, Multiple Myeloma | 343 |
| Beth Israel Deaconess Medical Center | Multiple Myeloma, Lymphoma, Acute Myeloid Leukemia | 263 |
| Boston Children's Hospital | Congenital Heart Disease, Cystic Fibrosis, Sickle Cell Disease | 259 |
| Dana Farber Cancer Institute | Breast Cancer, Ovarian Cancer, Prostate Cancer | 217 |
| Tufts Medical Center | Heart Failure, Acute Myeloid Leukemia, Acute Respiratory Distress Syndrome | 111 |
| Boston Medical Center | Amblyopia, Alpha1-Antitrypsin Deficiency, Anatomic Stage II Breast Cancer AJCC v8 | 95 |
| Massachusetts General Hospital Cancer Center | Breast Cancer, Coping Skills, B Acute Lymphoblastic Leukemia | 51 |
| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | Chronic Obstructive Pulmonary Disease, Mild Traumatic Brain Injury, Prostate Cancer | 29 |
| Brigham & Women's Hospital | Attention, Chronic Lymphocytic Leukemia, Critical Illness | 26 |
| Boston University | Obsessive-Compulsive Disorder, Adolescent Behavior Problem, Alzheimer Disease | 24 |
| Joslin Diabetes Center | Type 1 Diabetes Mellitus, Type 1 Diabetes (T1D), T1D | 22 |
| Mass General Brigham | Heart Failure, Heart Failure With Preserved Ejection Fraction, Advanced Solid Tumors | 22 |
| Northeastern University | Cognitive Change, Autism Spectrum Disorder (ASD), Healthy | 22 |
| Massachusetts Eye and Ear | Cone Rod Dystrophy, Glaucoma, Juvenile Macular Degeneration | 17 |
| Ophthalmic Consultants of Boston | Neovascular Age-related Macular Degeneration, Macular Edema Secondary to Inflammation, Age-Related Macular Degeneration | 13 |
| Adams Clinical Boston | Depressive Disorder, Major, Major Depressive Disorder, Alcohol Use Disorder | 12 |
| Brigham and Womens Hospital | Advanced Prostate Cancer, Alpha1-Antitrypsin Deficiency, Alzheimers Disease | 12 |
| Massachusetts Eye and Ear Infirmary | Laryngeal Dystonia, Stargardt Disease, Age-related Macular Degeneration | 12 |
| Clinical Trial Site | Transthyretin Amyloidosis With Cardiomyopathy, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency | 11 |
| Mass General Hospital | Biliary Tract Cancer (BTC), PDAC - Pancreatic Ductal Adenocarcinoma, AML | 11 |
| Beth Israel Deaconess Medical Center (BIDMC) | Prostate Cancer, Advanced Melanoma, Endometrial Cancer | 11 |
| Boston Childrens Hospital | CSTB-related Disease, Crohn's Disease, Cystic Fibrosis | 10 |
| Brigham and Women's Faulkner Hospital | Multimodal Analgesia, Opioid Consumption, Postoperative, Adverse Event | 8 |
Active & Upcoming Studies in Boston (2026)
Recruiting trials in Boston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (877 active studies)
- Early Intervention · Massachusetts General Hospital
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
Neurology & pain (218 active studies)
- Mindfulness Therapy for Chronic Pain After Intimate Partner Violence · Brigham and Women's Hospital
- Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · Brigham and Women's Hospital
Cardiovascular (189 active studies)
- Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · Brigham and Women's Hospital
- CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock · Phase 2 · Brigham and Women's Hospital
Diabetes & metabolic (97 active studies)
- Adiposity Distribution in Acute Respiratory Failure · Maurizio F. Cereda, MD
- Creating Linked Inpatient CGM for Kids · Boston Children's Hospital
Mental health & behavior (89 active studies)
- Whole Selves User Testing and Feasibility Study · Boston University
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
Pediatric (62 active studies)
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
- Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease · EARLY_Phase 1 · Massachusetts General Hospital
HIV / STI (33 active studies)
- Intervention to Reduce Implicit Bias in Pharmacies · Massachusetts General Hospital
- Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP · Boston Children's Hospital
Eye & vision (32 active studies)
- Glaucoma Drop Aids Part 2 · Boston Medical Center
- Study of Remimazolam for Cataract Surgery · Phase 4 · Fred E, Shapiro
Vaccines (15 active studies)
- Sauna for Long Covid · Massachusetts General Hospital
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Boston
- Breast Cancer (64 active studies)
- Prostate Cancer (41 active studies)
- Ovarian Cancer (36 active studies)
- Heart Failure (34 active studies)
- Acute Myeloid Leukemia (32 active studies)
- Advanced Solid Tumor (31 active studies)
Leading research sponsors in Boston
- Massachusetts General Hospital
- Brigham and Women's Hospital
- Boston Children's Hospital
- Dana-Farber Cancer Institute
- Beth Israel Deaconess Medical Center
Frequently asked questions
How many paid clinical trials are currently recruiting in Boston?
There are approximately 2,887 recruiting clinical trials in Boston, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Boston pay participants?
Most recruiting trials in Boston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Boston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Boston?
The most common conditions under active study in Boston include Breast Cancer (64), Prostate Cancer (41), Ovarian Cancer (36), Heart Failure (34), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Boston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Boston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Boston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Boston?
Recruiting research sites in Boston include Massachusetts General Hospital, Brigham and Women's Hospital, Dana-Farber Cancer Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Boston right now?
The largest active categories in Boston are Cancer & tumors (877), Neurology & pain (218), Cardiovascular (189). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
Other cities in Massachusetts
Worcester, MA(208)Burlington, MA(81)Springfield, MA(74)Waltham, MA(58)Cambridge, MA(47)Belmont, MA(46)Charlestown, MA(41)Foxborough, MA(36)Newton, MA(32)Watertown, MA(30)Methuen, MA(24)Milford, MA(24)Brighton, MA(23)Peabody, MA(23)New Bedford, MA(22)Chestnut Hill, MA(18)Beverly, MA(17)Fall River, MA(14)South Weymouth, MA(14)Gloucester, MA(13)Brookline, MA(12)Bedford, MA(11)Plymouth, MA(11)Lowell, MA(9)Needham, MA(9)North Dartmouth, MA(9)Quincy, MA(9)Stoneham, MA(9)Weymouth, MA(9)Danvers, MA(8)Lexington, MA(8)Natick, MA(7)South Dartmouth, MA(7)Amherst, MA(6)Framingham, MA(6)Jamaica Plain, MA(6)Winchester, MA(6)Roslindale, MA(5)Salem, MA(5)Wellesley, MA(5)Westborough, MA(5)Andover, MA(4)Holyoke, MA(4)Malden, MA(4)Marlborough, MA(4)North Worcester, MA(4)Somerville, MA(4)Braintree, MA(3)Brockton, MA(3)Fairhaven, MA(3)Lawrence, MA(3)Pittsfield, MA(3)Shrewsbury, MA(3)West Roxbury, MA(3)Acton, MA(2)Allston, MA(2)Chelsea, MA(2)Hyannis, MA(2)Hyde Park, MA(2)Medford, MA(2)