Oncology Clinical Trials in Cincinnati, OH
As of August 2026, 177 paid clinical trials are recruiting for Oncology in Cincinnati, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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177 clinical trials for Oncology
·Clear filters·A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
Top Research Study Locations in Cincinnati
Researchers run research studies in Cincinnati, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cincinnati Children's Hospital Medical Center | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Neuroblastoma | 273 |
| University of Cincinnati | Chronic Lymphocytic Leukemia, Stroke, Multiple Myeloma | 100 |
| University of Cincinnati Medical Center | Advanced Solid Tumor, Interstitial Lung Disease, Stroke | 69 |
| Cincinnati Children's Hospital | Amblyopia, Musculoskeletal Pain, Acute Kidney Injury | 48 |
| University of Cincinnati Cancer Center-UC Medical Center | Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | 44 |
| The Christ Hospital | Heart Failure, Tricuspid Regurgitation, Advanced Solid Tumor | 40 |
| Bethesda North Hospital | Malignant Solid Neoplasm, Ovarian Carcinoma, Plasma Cell Myeloma | 31 |
| Good Samaritan Hospital - Cincinnati | Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm, Anatomic Stage I Breast Cancer AJCC v8 | 31 |
| TriHealth Cancer Institute-Anderson | Malignant Solid Neoplasm, Ovarian Carcinoma, Plasma Cell Myeloma | 22 |
| TriHealth Cancer Institute-Westside | Malignant Solid Neoplasm, Ovarian Carcinoma, Plasma Cell Myeloma | 22 |
| CTI Clinical Research Center | Obesity, Overweight, Obstructive Sleep Apnea | 14 |
| Cincinnati Eye Institute | Stargardt Disease, Cone Rod Dystrophy, Juvenile Macular Degeneration | 14 |
| Oncology Hematology Care | Multiple Myeloma, Breast Cancer, Acute Myeloid Leukemia (AML) | 14 |
| Oncology Hematology Care Inc-Kenwood | Acral Lentiginous Melanoma, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 11 |
| University of Cincinnati College of Medicine | Acetabular Fracture, Acupuncture, Adolescents | 9 |
| Good Samaritan Hospital | Atrial Fibrillation, Chronic Subdural Hematoma, Deep Vein Thrombosis | 8 |
| University of Cincinnati Cancer Center | Colorectal Cancer, Anaplastic Lymphoma Kinase-positive, Cutaneous Melanoma | 8 |
| Cincinnati Childrens Hospital Medical Center | Adrenal Insufficiency, Alopecia, Areata Alopecia | 7 |
| Cinn Children Hosp Medical Center | Chronic Myelogenous Leukemia, Cryptosporidiosis, Leukemia, Myelogenous, Chronic, Philadelphia Chromosome Positive | 6 |
| GSK Investigational Site | Asthma, Chickenpox, Colonic Neoplasms | 6 |
| Oncology Hematology Care Clinical Trials, LLC | Carcinoma, Non-Small-Cell Lung, Chronic Graft-Versus-Host Disease (cGVHD), Esophageal Adenocarcinoma | 5 |
| Alkermes Investigational Site | Narcolepsy Type 1, Narcolepsy Type 2, Bipolar I Disorder | 5 |
| Clinical Trial Site | Breast Cancer, ER Positive Breast Cancer, HER2 Negative Breast Carcinoma | 5 |
| Children's Hospital Medical Center | Biliary Atresia, Duchenne Muscular Dystrophy, Essential Fatty Acid Deficiency | 5 |
| Christ Hospital | Acute or Chronic Coronary Artery Disease, Cardiovascular Diseases, Coronary Artery Disease | 5 |
Active & Upcoming Studies in Cincinnati (2026)
Recruiting trials in Cincinnati grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (282 active studies)
- A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer · Children's Hospital Medical Center, Cincinnati
- Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin · Phase 3 · NRG Oncology
Cardiovascular (92 active studies)
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event · Phase 2 · Eli Lilly and Company
- A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation · Biosense Webster, Inc.
Neurology & pain (73 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy · Phase 2, Phase 3 · Jazz Pharmaceuticals
Diabetes & metabolic (36 active studies)
- GLP-1 RA for Stage 1 Type 1 Diabetes · Phase 2 · Children's Hospital Medical Center, Cincinnati
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event · Phase 2 · Eli Lilly and Company
Pediatric (36 active studies)
- Adapting Enhanced Supports to Improve Patient Adherence to Secondary Antibiotic Prophylaxis for Rheumatic Heart Disease · Children's Hospital Medical Center, Cincinnati
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Mental health & behavior (23 active studies)
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
Eye & vision (13 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults · Astellas Pharma Global Development, Inc.
Vaccines (9 active studies)
- A Study of Secutrelvir in Participants With Coronavirus Disease 2019 (COVID-19) Who Are at High Risk for Progression to Severe Disease · Phase 3 · Shionogi
- A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
HIV / STI (7 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Health-E You Efficacy Trial for Male Adolescents · Johns Hopkins University
Common conditions studied in Cincinnati
- Heart Failure (19 active studies)
- Obesity (19 active studies)
- Overweight (12 active studies)
- Breast Cancer (11 active studies)
- Multiple Myeloma (11 active studies)
- Cystic Fibrosis (10 active studies)
Leading research sponsors in Cincinnati
- Children's Hospital Medical Center, Cincinnati
- University of Cincinnati
- National Cancer Institute (NCI)
- AstraZeneca
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in Cincinnati?
There are approximately 1,081 recruiting clinical trials in Cincinnati, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cincinnati pay participants?
Most recruiting trials in Cincinnati compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cincinnati?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cincinnati?
The most common conditions under active study in Cincinnati include Heart Failure (19), Obesity (19), Overweight (12), Breast Cancer (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cincinnati?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cincinnati on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cincinnati?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cincinnati?
Recruiting research sites in Cincinnati include Cincinnati Children's Hospital Medical Center, University of Cincinnati, University of Cincinnati Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cincinnati right now?
The largest active categories in Cincinnati are Cancer & tumors (282), Cardiovascular (92), Neurology & pain (73). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.