Oncology Clinical Trials in Jacksonville, FL
As of August 2026, 203 paid clinical trials are recruiting for Oncology in Jacksonville, Florida. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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203 clinical trials for Oncology
·Clear filters·A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
Top Research Study Locations in Jacksonville
Researchers run research studies in Jacksonville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic in Florida | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 170 |
| Mayo Clinic | Amyotrophic Lateral Sclerosis, Colorectal Cancer, Breast Cancer | 83 |
| Mayo Clinic Florida | Amyotrophic Lateral Sclerosis, Advanced Melanoma, CRC | 75 |
| Mayo Clinic Jacksonville | Non Small Cell Lung Cancer, Amyotrophic Lateral Sclerosis (ALS), Prostate Cancer | 47 |
| Nemours Children's Clinic-Jacksonville | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 32 |
| Jacksonville Center for Clinical Research | Obesity, Heart Failure, Overweight | 23 |
| Baptist MD Anderson Cancer Center | Breast Cancer, Advanced Melanoma, Anatomic Stage II Breast Cancer AJCC v8 | 18 |
| Cancer Specialists of North Florida | Carcinoma, Non-Small-Cell Lung, Acinar Cell Carcinoma, Advanced Cancer | 13 |
| University of Florida | Coronary Artery Disease, Allergies, Arthropathy of Hip | 12 |
| Mayo Clinic - Jacksonville | Adenoid Cystic Carcinoma, Amyloid Cardiomyopathy, Amyloidosis | 10 |
| Brooks Rehabilitation | Spinal Cord Injuries, Spinal Cord Injury, Stroke | 9 |
| Ascension St. Vincent's | Atrial Fibrillation, Brain Tumor, Brain Tumor - Metastatic | 8 |
| Mayo Clinic - Florida | Epilepsy, Epilepsy (Treatment Refractory), Astrocytoma, Grade IV | 8 |
| University of Florida Jacksonville | Coronary Artery Disease, AV Block, Acute Stroke | 8 |
| Baptist Health Research Institute | Acute Ischemic Stroke, Alzheimer Disease, Aneurysm, Intracranial | 7 |
| UF Health Jacksonville | Atrial Fibrillation, Diabetes Mellitus, Type 2, Heart Failure | 7 |
| Baptist Medical Center Jacksonville | Intracranial Aneurysm, Chronic Subdural Hematoma, Intracranial Atherosclerotic Stenosis (ICAS) | 6 |
| Clinical Neuroscience Solutions, Inc. | Bipolar Depression, Bipolar Disorder, Bipolar I Disorder | 6 |
| Mayo Clinic Cancer Center | Acute Myeloid Leukemia, B-Cell Acute Lymphoblastic Leukaemia, CRC | 6 |
| First Coast Cardiovascular Institute | Heart Failure, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia | 5 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Gastrointestinal Neoplasms, Irritable Bowel Syndrome | 5 |
| Nemours Children's Clinic | Cystic Fibrosis, Amblyopia, Cystic Fibrosis Pulmonary Exacerbation | 5 |
| Nemours Children's Health | Asthma (Diagnosis), Autosomal Dominant Hypocalcemia Type 1 (ADH1), Child | 5 |
| Clinical Trial Site | ATTR Amyloidosis, Advanced Hepatocellular Carcinoma, Generalized Myasthenia Gravis | 4 |
| Brooks Rehabilitation Hospital | Internuclear Ophthalmoplegia, Ischemic Stroke, Palsy, Abducens | 4 |
Active & Upcoming Studies in Jacksonville (2026)
Recruiting trials in Jacksonville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (301 active studies)
Cardiovascular (67 active studies)
Neurology & pain (53 active studies)
- Magnesium Supplement for Sleep Quality in Women With Poor Sleep · Jacksonville University
- Arm Elevation for Prevention of Propofol Injection Pain · Mayo Clinic
Diabetes & metabolic (50 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight · Phase 3 · Novo Nordisk A/S
Mental health & behavior (17 active studies)
- A Study to Evaluate the Efficacy and Safety of AXS-05 for Smoking Cessation in Adults · Phase 3 · Axsome Therapeutics, Inc.
- A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder · Phase 3 · Otsuka Pharmaceutical Development & Commercialization, Inc.
HIV / STI (8 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System · University of Florida
Eye & vision (8 active studies)
- Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration · Phase 2 · Adverum Biotechnologies, Inc.
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (6 active studies)
Vaccines (2 active studies)
Common conditions studied in Jacksonville
- Obesity (21 active studies)
- Malignant Solid Neoplasm (19 active studies)
- Breast Cancer (16 active studies)
- Heart Failure (16 active studies)
- Overweight (15 active studies)
- Prostate Cancer (13 active studies)
Leading research sponsors in Jacksonville
- Mayo Clinic
- AstraZeneca
- University of Florida
- Children's Oncology Group
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Jacksonville?
There are approximately 924 recruiting clinical trials in Jacksonville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Jacksonville pay participants?
Most recruiting trials in Jacksonville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Jacksonville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Jacksonville?
The most common conditions under active study in Jacksonville include Obesity (21), Malignant Solid Neoplasm (19), Breast Cancer (16), Heart Failure (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Jacksonville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Jacksonville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Jacksonville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Jacksonville?
Recruiting research sites in Jacksonville include Mayo Clinic in Florida, Mayo Clinic, Mayo Clinic Florida, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Jacksonville right now?
The largest active categories in Jacksonville are Cancer & tumors (301), Cardiovascular (67), Neurology & pain (53). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.