Blood cancer Clinical Trials in Orange, CA
As of September 2026, 32 paid clinical trials are recruiting for Blood cancer in Orange, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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32 clinical trials for Blood cancer
·Clear filters·A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
A Long-term Extension Study of PCI-32765 (Ibrutinib)
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)
A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma
A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia
A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
Project: Every Child for Younger Patients With Cancer
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness
Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow
Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Top Research Study Locations in Orange
Researchers run research studies in Orange, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Children's Hospital of Orange County | B Acute Lymphoblastic Leukemia, Neuroblastoma, Recurrent Malignant Solid Neoplasm | 68 |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Stage IV Colorectal Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Metastatic Malignant Solid Neoplasm | 62 |
| University of California Irvine | Amyotrophic Lateral Sclerosis, Anticoagulants, Carcinoma, Non-Small-Cell Lung | 27 |
| Chao Family Comprehensive Cancer Center, University of California, Irvine | Glioma, Hepatocellular Carcinoma, Pancreatic Cancer | 21 |
| University of California Irvine Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 20 |
| University of California, Irvine | Myasthenia Gravis, Parkinson Disease, Acute Myeloid Leukemia (AML) | 17 |
| UC Irvine Health | Multiple Myeloma, Aortic Stenosis, B-cell Malignancy | 14 |
| UC Irvine Medical Center | Advanced Metastatic Castration Resistant Prostate Cancer, Atrial Fibrillation, Autosomal Dominant Polycystic Kidney Disease | 12 |
| NRC Research Institute | Bipolar Disorder, Bipolar I Disorder, Bipolar Depression | 10 |
| ATP Clinical Research | Bipolar Disorder, Alzheimer's Disease, Bipolar Depression | 9 |
| Chao Family Comprehensive Cancer Center University of California, Irvine | Melanoma (Skin), Cervical Cancer, Chronic Myeloid Leukemia | 8 |
| University of California, Irvine (UCI) Health - UC Irvine Medical Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 8 |
| University of California, Irvine Medical Center | Cancer, Lung, Cardiovascular Diseases, Colorectal Cancer; Lung Cancer | 8 |
| Children's Hospital Orange County | ALL, AML, Acute Undifferentiated Leukemia | 7 |
| Saint Joseph Hospital - Orange | Advanced Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 7 |
| UC Irvine Health - Chao Family Comprehensive Cancer Center | Gastric Cancer, Hepatocellular Carcinoma, Acute Myeloid Leukemia | 6 |
| UCI Health | Cancer, Crohn's Disease, Fatigue Related to Cancer Treatment | 5 |
| Chao Family Comprehensive Cancer Center | Chronic Lymphocytic Leukemia, Advanced Clear Cell Renal Cell Carcinoma, Endometrial Cancer | 4 |
| Chao Family Comprehensive Cancer Center, University of California Irvine | Allogeneic Stem Cell Transplantation, Breast Cancer, Colorectal Cancer | 4 |
| Children's Hospital of Orange County (CHOC) | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Anti-myostatin | 4 |
| Knowledge Research Center | Colonic Polyps, MASH - Metabolic Dysfunction-Associated Steatohepatitis, Metabolic Dysfunction-Associated Steatotic Liver Disease | 4 |
| Neurocrine Clinical Site | Major Depressive Disorder, Bipolar Disorder, Schizoaffective Disorder | 4 |
| UC Irvine | Autoimmune Encephalitis, Encephalitis, Overactive Bladder (OAB) | 4 |
| UCI Medical Center | Deep Venous Thrombosis, Locally Advanced Solid Tumor, Metastatic Solid Tumor | 4 |
| Center for Inherited Blood Disorders | Hemophilia A, Hemophilia B | 3 |
Active & Upcoming Studies in Orange (2026)
Recruiting trials in Orange grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (222 active studies)
- Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma · Phase 1 · National Cancer Institute (NCI)
- Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma · Phase 2 · University of California, Irvine
Cardiovascular (19 active studies)
- Optimal Ventilation for Cardiac Arrest · Children's Hospital of Philadelphia
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Mental health & behavior (18 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Neurology & pain (18 active studies)
- A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE) · Phase 4 · Alpha Cognition, Inc
- Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study · University of California, Irvine
Diabetes & metabolic (14 active studies)
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Pediatric (8 active studies)
- A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors · Phase 1 · Neonc Technologies, Inc.
- Pediatric Down Syndrome Post-Approval Study · Inspire Medical Systems, Inc.
Vaccines (2 active studies)
- Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS) · Children's Hospital of Orange County
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
Eye & vision (1 active study)
- The Myelin Disorders Biorepository Project · Children's Hospital of Philadelphia
Common conditions studied in Orange
- Breast Cancer (9 active studies)
- Ovarian Cancer (9 active studies)
- Acute Myeloid Leukemia (8 active studies)
- Major Depressive Disorder (8 active studies)
- Endometrial Cancer (7 active studies)
- Gastric Cancer (7 active studies)
Leading research sponsors in Orange
- University of California, Irvine
- National Cancer Institute (NCI)
- Children's Oncology Group
- Eli Lilly and Company
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Orange?
There are approximately 517 recruiting clinical trials in Orange, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Orange pay participants?
Most recruiting trials in Orange compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Orange?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Orange?
The most common conditions under active study in Orange include Breast Cancer (9), Ovarian Cancer (9), Acute Myeloid Leukemia (8), Major Depressive Disorder (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Orange?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Orange on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Orange?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Orange?
Recruiting research sites in Orange include Children's Hospital of Orange County, UC Irvine Health/Chao Family Comprehensive Cancer Center, University of California Irvine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Orange right now?
The largest active categories in Orange are Cancer & tumors (222), Cardiovascular (19), Mental health & behavior (18). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.