Clinical Trials at University of California Irvine
As of August 2026, 25 paid clinical trials are recruiting at University of California Irvine, located at 333 CITY BLVD W STE 2100, ORANGE, CA 92868-2949, phone (714) 456-6719 in Orange, California. Active studies at this site cover conditions such as Breast Cancer, Ovarian Cancer and Acute Myeloid Leukemia. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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25 clinical trials at University of California Irvine
·Clear filters·Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)
Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant
Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma
EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures
Collaboration for Down Syndrome Progress (CDP)
PREVENT ALL ALS Study
Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3
Common conditions studied in Orange
- Breast Cancer (10 active studies)
- Ovarian Cancer (9 active studies)
- Acute Myeloid Leukemia (8 active studies)
- Hepatocellular Carcinoma (8 active studies)
- Major Depressive Disorder (8 active studies)
- Endometrial Cancer (7 active studies)
Leading research sponsors in Orange
- University of California, Irvine
- National Cancer Institute (NCI)
- Children's Oncology Group
- NRG Oncology
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Orange?
There are approximately 508 recruiting clinical trials in Orange, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Orange pay participants?
Most recruiting trials in Orange compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Orange?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Orange?
The most common conditions under active study in Orange include Breast Cancer (10), Ovarian Cancer (9), Acute Myeloid Leukemia (8), Hepatocellular Carcinoma (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Orange?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Orange on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Orange?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Orange?
Recruiting research sites in Orange include Children's Hospital of Orange County, UC Irvine Health/Chao Family Comprehensive Cancer Center, University of California Irvine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Orange right now?
The largest active categories in Orange are Cancer & tumors (214), Cardiovascular (19), Mental health & behavior (18). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of California Irvine?
University of California Irvine is located at 333 CITY BLVD W STE 2100, ORANGE, CA 92868-2949. Use the Google Maps link in the intro above to get directions.
How do I contact University of California Irvine?
You can reach University of California Irvine by phone at (714) 456-6719. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.