Clinical Trials at Hospital of the University of Pennsylvania
As of August 2026, 79 paid clinical trials are recruiting at Hospital of the University of Pennsylvania, located at 2121 MARKET ST APT 220, PHILADELPHIA, PA 19103-1309, phone (585) 235-7653 in Philadelphia, Pennsylvania. Active studies at this site cover conditions such as Breast Cancer, Heart Failure and Ovarian Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Philadelphia
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention
82 clinical trials at Hospital of the University of Pennsylvania
·Clear filters·Assessment of CCM in HF With Higher Ejection Fraction
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
The THOR IDE Study
Nectero EAST System Clinical Study
Prevail Global Study
Registry for Stage 2 Type 1 Diabetes
Zenith® Fenestrated+ Clinical Study
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).
Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late-Onset Pompe Disease (PROGRESS-GT LOPD)
Neuralert Stroke Monitor Trial
TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas
Valved Graft PMCF Study
Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
ViewFlex X ICE First-in-Human Study
Cholate Clearance in Fontan and Heart Failure
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT
The Neuralert Stroke Monitor Pilot Trial
Supraglottic Airway for Resuscitation in Preemies
Early General Anesthesia to Limit Experiences of Trauma During Cesarean Section-Pilot Study
Window Study of Intratumoral Mitazalimab in Breast Cancer (WINIT-BC)
Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer
Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
Common conditions studied in Philadelphia
- Breast Cancer (35 active studies)
- Cancer (24 active studies)
- Heart Failure (21 active studies)
- Ovarian Cancer (21 active studies)
- Prostate Cancer (21 active studies)
- Advanced Solid Tumor (18 active studies)
Leading research sponsors in Philadelphia
- University of Pennsylvania
- Abramson Cancer Center at Penn Medicine
- Children's Hospital of Philadelphia
- Thomas Jefferson University
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Philadelphia?
There are approximately 1,975 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Philadelphia pay participants?
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Philadelphia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Philadelphia?
The most common conditions under active study in Philadelphia include Breast Cancer (35), Cancer (24), Heart Failure (21), Ovarian Cancer (21), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Philadelphia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Philadelphia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Philadelphia?
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Philadelphia right now?
The largest active categories in Philadelphia are Cancer & tumors (555), Neurology & pain (111), Cardiovascular (107). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Hospital of the University of Pennsylvania?
Hospital of the University of Pennsylvania is located at 2121 MARKET ST APT 220, PHILADELPHIA, PA 19103-1309. Use the Google Maps link in the intro above to get directions.
How do I contact Hospital of the University of Pennsylvania?
You can reach Hospital of the University of Pennsylvania by phone at (585) 235-7653. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.