Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients
for Malnutitrion
1 location in Philadelphia
Sponsor: Fox Chase Cancer Center
Sex: All·Age: 18+
Code: NCT07776704·Recruiting·Listed Aug 20, 2026
Cancer (any) Clinical Trials in Philadelphia, PA
As of September 2026, 32 paid clinical trials are recruiting for Cancer (any) in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Philadelphia
Filter results
Filter results
Newly added in Philadelphia
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
33 clinical trials for Cancer (any)
·Clear filters· Email me when a new cancer (any) trial opens in Philadelphia, PA.
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
for Neoplasms
Sites in Philadelphia, Pittsburgh +75 more locations
Sponsor: Celgene
Sex: All·Age: All ages
Code: NCT03435796·Phase 2, Phase 3·Recruiting·Listed Feb 2018
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
for Advanced Cancer
Sites in Philadelphia +37 more locations
Sponsor: Artios Pharma Ltd
Sex: All·Age: 18+
Code: NCT04657068·Phase 1, Phase 2·Recruiting·Listed Dec 2020
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
for Advanced Solid Tumor
Sites in Philadelphia, York +29 more locations
Sponsor: PMV Pharmaceuticals, Inc
Sex: All·Age: 12+
Code: NCT04585750·Phase 1, Phase 2·Recruiting·Listed Oct 2020
FOG-001 in Locally Advanced or Metastatic Solid Tumors
for Cancer
Sites in Philadelphia, Pittsburgh +28 more locations
Sponsor: Parabilis Medicines, Inc.
Sex: All·Age: 18+
Code: NCT05919264·Phase 1, Phase 2·Recruiting·Listed Jun 2023
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
for Cancer, Metastatic
Sites in Philadelphia +66 more locations
Sponsor: Massive Bio, Inc.
Sex: All·Age: All ages
Code: NCT03452774·Recruiting·Listed Mar 2018
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
for Neoplasms
Sites in Philadelphia +14 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06150157·Phase 1·Recruiting·Listed Nov 2023
SLV-154 Treatment of Advanced Cancers
for Advanced Cancer
Sites in Philadelphia +11 more locations
Sponsor: Solve Therapeutics
Sex: All·Age: 12+
Code: NCT06771219·Phase 1·Recruiting·Listed Jan 2025
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
for Malignant Neoplasm
Sites in Philadelphia +16 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 1 Month - 17
Code: NCT06941272·Phase 1, Phase 2·Recruiting·Listed Apr 2025
Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.
for Metastatic Cancer
Drug: Apalutamide
Sites in Philadelphia +11 more locations
Sponsor: Sun Pharmaceutical Industries Limited
Sex: Male·Age: 18+
Code: NCT05422911·Phase 2·Recruiting·Listed Jun 2022
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
for Refractory Cancer
Drug: Nivolumab
Sites in Philadelphia, Pittsburgh +11 more locations
Sponsor: Immatics US, Inc.
Sex: All·Age: 18+
Code: NCT03686124·Phase 1, Phase 2·Recruiting·Listed Sep 2018
A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
for Cancer
Sites in Philadelphia +10 more locations
Sponsor: Conjupro Biotherapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05948865·Phase 1·Recruiting·Listed Jul 2023
Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors
for Cancer
Sites in Philadelphia +14 more locations
Sponsor: MBrace Therapeutics
Sex: All·Age: 18+
Code: NCT06014658·Phase 1, Phase 2·Recruiting·Listed Aug 2023
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
for Malignant Neoplasm
Sites in Philadelphia +12 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 1 Month - 17
Code: NCT07630974·Phase 1, Phase 2·Recruiting·Listed Jun 2026
Engaging M-health for Symptom Monitoring and Health Promotion for Women on Endocrine Therapy for Breast Cancer (EmSHAPE)
for Cancer
1 location in Philadelphia
Sponsor: Abramson Cancer Center at Penn Medicine
Sex: Female·Age: 18+
Code: NCT07454499·Recruiting·Listed Mar 2026
Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)
for Cancer
1 location in Philadelphia
Sponsor: Abramson Cancer Center at Penn Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07471958·Recruiting·Listed Mar 2026
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in Philadelphia, Allentown +225 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
Abatacept in Immune Checkpoint Inhibitor Myocarditis
for Myocarditis Acute
Sites in Philadelphia, Bethlehem +27 more locations
Sponsor: Massachusetts General Hospital
Sex: All·Age: 18+
Code: NCT05335928·Phase 3·Recruiting·Listed Apr 2022
IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer
for Cancer
Sites in Philadelphia +1 more location
Sponsor: State University of New York at Buffalo
Sex: All·Age: 18+
Code: NCT06206941·Recruiting·Listed Jan 2024
Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)
for Differentiated Thyroid Cancer
Sites in Philadelphia +3 more locations
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 2 - 25
Code: NCT06458036·Phase 2·Recruiting·Listed Jun 2024
Childhood Cancer Survivor Study
for Cancer
Sites in Philadelphia, Pittsburgh +25 more locations
Sponsor: St. Jude Children's Research Hospital
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT01120353·Recruiting·Listed May 2010
Evaluation of Grief Therapy Approaches for Bereaved Parents
for Grief
Sites in Philadelphia +4 more locations
Sponsor: University of Miami
Sex: All·Age: 18+
Code: NCT05142605·Recruiting·Listed Dec 2021
From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care
for Cancer
1 location in Philadelphia
Sponsor: Thomas Jefferson University
Sex: All·Age: 18+
Code: NCT07352579·Recruiting·Listed Jan 2026
Massage Impact on Sleep in Pediatric Oncology
for Cancer
Sites in Philadelphia +1 more location
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 12 - 21
Code: NCT06892158·Recruiting·Listed Mar 2025
Re-Engaging AYA Survivors in Cancer-Related Healthcare
for Cancer
Sites in Philadelphia +2 more locations
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 15 - 29
Code: NCT07138040·Recruiting·Listed Aug 2025
Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)
for Geriatric Assessment
Sites in Philadelphia, Lancaster +1 more location
Sponsor: Abramson Cancer Center at Penn Medicine
Sex: All·Age: 70+
Code: NCT06870617·Recruiting·Listed Mar 2025
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
for Neoplasms
Sites in Philadelphia, Pottstown +11 more locations
Sponsor: The Radiosurgery Society
Sex: All·Age: All ages
Code: NCT01885299·Recruiting·Listed Jun 2013
Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients
for Cancer
1 location in Philadelphia
Sponsor: Thomas Jefferson University
Sex: All·Age: 18+
Code: NCT03245411·Recruiting·Listed Aug 2017
eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer
for Cancer
1 location in Philadelphia
Sponsor: Abramson Cancer Center at Penn Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05427240·Recruiting·Listed Jun 2022
Autoimmunity After Checkpoint Blockade
for Autoimmunity
1 location in Philadelphia
Sponsor: Abramson Cancer Center at Penn Medicine
Sex: All·Age: 18+
Code: NCT04119713·Recruiting·Listed Oct 2019
Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer
for Differentiated Thyroid Cancer
Sites in Philadelphia +4 more locations
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 2 - 99
Code: NCT05783323·Phase 2·Recruiting·Listed Mar 2023
Cannabis Use and Outcomes in Black and White Patients With Cancer
for Cancer
Sites in Philadelphia +2 more locations
Sponsor: State University of New York at Buffalo
Sex: All·Age: 21 - 99
Code: NCT06037681·Recruiting·Listed Sep 2023
First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors
for Neoplasms
Sites in Philadelphia +1 more location
Sponsor: GlaxoSmithKline
Sex: All·Age: 18+
Code: NCT07438782·Phase 1·Recruiting·Listed Feb 2026
Top Research Study Locations in Philadelphia
Researchers run research studies in Philadelphia, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pennsylvania | Heart Failure, Opioid Use Disorder, Colorectal Cancer | 359 |
| Children's Hospital of Philadelphia | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Pediatric Cancer | 303 |
| Thomas Jefferson University Hospital | Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage I Breast Cancer AJCC v8 | 106 |
| Fox Chase Cancer Center | Breast Cancer, Cancer, Urothelial Carcinoma | 95 |
| Thomas Jefferson University | Focal Epilepsy, Advanced Melanoma, Anemia | 95 |
| Hospital of the University of Pennsylvania | Abdominal Aortic Aneurysm, Breast Cancer, Aortic Dissection | 88 |
| Temple University | Amyotrophic Lateral Sclerosis, COPD, Emphysema | 41 |
| The Children's Hospital of Philadelphia | Mitochondrial Diseases, Primary Mitochondrial Disease, 4H Syndrome | 40 |
| Temple University Hospital | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, COPD | 34 |
| University of Pennsylvania/Abramson Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 30 |
| Pennsylvania Hospital | Stroke, Acute, Activity Restriction, Advanced Cancer | 28 |
| Penn Presbyterian Medical Center | Heart Failure, ADHF, AV Block | 25 |
| Abramson Cancer Center of the University of Pennsylvania | Breast Cancer, Advanced Solid Tumor, Diffuse Large B Cell Lymphoma | 24 |
| Saint Christopher's Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 22 |
| Jefferson Torresdale Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 21 |
| Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA | Parkinson Disease, Stress Disorders, Post-Traumatic, Advanced Urothelial Carcinoma | 19 |
| Sidney Kimmel Cancer Center at Thomas Jefferson University | Breast Cancer, Colorectal Cancer, Cancer | 15 |
| Penn Medicine | Hypertension, ALS, Allogeneic Transplantation | 14 |
| University of Pennsylvania Hospital | Chronic Lymphocytic Leukemia, Neoplasm Metastasis, Non-Hodgkin Lymphoma | 13 |
| University of Pennsylvania, Abramson Cancer Center | Advanced Solid Tumor, Biliary Tract Cancer, Breast Cancer | 13 |
| GSK Investigational Site | Asthma, Connective Tissue Diseases, Gastrointestinal Neoplasms | 12 |
| Drexel University | Autism Spectrum Disorder, Anxiety, Attention Deficit and Disruptive Behavior Disorders | 12 |
| Abramson Cancer Center at University of Pennsylvania | Cardiotoxicity, Renal Cell Carcinoma, AML, Adult | 10 |
| Childrens Hospital of Philadelphia | Suicide, Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR) | 10 |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | Advanced Solid Tumor, Colorectal Cancer, Bladder Cancer | 10 |
Active & Upcoming Studies in Philadelphia (2026)
Recruiting trials in Philadelphia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (555 active studies)
- Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse · Phase 2 · National Cancer Institute (NCI)
- A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information · Children's Oncology Group
Cardiovascular (113 active studies)
- Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST Trial · Phase 3 · The George Washington University Biostatistics Center
- Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass-Substudy · University of Pennsylvania
Neurology & pain (106 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease · Phase 4 · VA Office of Research and Development
Diabetes & metabolic (61 active studies)
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities · Phase 3 · Ascletis Pharma (China) Co., Limited
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Mental health & behavior (49 active studies)
- NST-SPARK Open-Label Phase 1 STTR (IGNITE) · North Shore Therapeutics, Inc.
- Optimizing Stimulation Parameters for Electroconvulsive Therapy · University of Pennsylvania
Pediatric (47 active studies)
- Bilevel Positive Airway Pressure (BPAP) for Severe Asthma · Columbia University
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
HIV / STI (28 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy · International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Eye & vision (22 active studies)
- Penn SICCA Follow-up Study · University of Pennsylvania
- A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME) · Phase 1 · Genentech, Inc.
Vaccines (7 active studies)
- A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age · Phase 3 · GlaxoSmithKline
- Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older · Phase 1, Phase 2 · Sanofi
Common conditions studied in Philadelphia
- Breast Cancer (37 active studies)
- Cancer (23 active studies)
- Ovarian Cancer (23 active studies)
- Heart Failure (22 active studies)
- Prostate Cancer (21 active studies)
- Advanced Solid Tumor (19 active studies)
Leading research sponsors in Philadelphia
- University of Pennsylvania
- Abramson Cancer Center at Penn Medicine
- Children's Hospital of Philadelphia
- Thomas Jefferson University
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Philadelphia?
There are approximately 1,988 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Philadelphia pay participants?
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Philadelphia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Philadelphia?
The most common conditions under active study in Philadelphia include Breast Cancer (37), Cancer (23), Ovarian Cancer (23), Heart Failure (22), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Philadelphia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Philadelphia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Philadelphia?
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Philadelphia right now?
The largest active categories in Philadelphia are Cancer & tumors (555), Cardiovascular (113), Neurology & pain (106). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
Other cities in Pennsylvania
Pittsburgh, PA(1,240)Hershey, PA(268)Danville, PA(126)Allentown, PA(125)Bethlehem, PA(96)York, PA(90)Erie, PA(86)Wilkes-Barre, PA(72)Lancaster, PA(69)Monroeville, PA(63)Harrisburg, PA(56)Wynnewood, PA(52)Willow Grove, PA(46)Lewisburg, PA(45)Hazleton, PA(43)Mechanicsburg, PA(42)East Stroudsburg, PA(38)West Reading, PA(38)Greensburg, PA(34)Media, PA(34)Duncansville, PA(32)Sayre, PA(32)Dickson City, PA(30)Scranton, PA(30)Uniontown, PA(30)DuBois, PA(29)Chadds Ford, PA(28)University Park, PA(28)Chambersburg, PA(27)Lebanon, PA(26)Beaver, PA(25)Camp Hill, PA(25)West Chester, PA(24)Wyomissing, PA(24)Bala-Cynwyd, PA(23)Ephrata, PA(22)Farrell, PA(22)Gettysburg, PA(22)Plymouth Meeting, PA(22)Pottsville, PA(22)Washington, PA(22)Wexford, PA(22)Indiana, PA(21)Paoli, PA(21)Seneca, PA(21)Bryn Mawr, PA(20)Easton, PA(20)Jefferson Hills, PA(20)Johnstown, PA(20)New Castle, PA(20)State College, PA(19)Altoona, PA(18)Butler, PA(18)Smithfield, PA(18)Abington, PA(17)Cranberry Township, PA(17)Natrona Heights, PA(16)Carlisle, PA(15)Horsham, PA(15)N. Huntingdon, PA(14)