The AYA Oncology Self-care Movement
for Acute Lymphobkastic Leukemia
Sites in Philadelphia +3 more locations
Sponsor: Northwestern University
Sex: All·Age: 15 - 25
Code: NCT07724652·Not Yet Recruiting·Listed Jul 24, 2026
Clinical Trials at The Children's Hospital of Philadelphia
As of September 2026, 32 paid clinical trials are recruiting at The Children's Hospital of Philadelphia, located at 34TH & CIVIC CENTER AVE, PHILADELPHIA, PA 19104, phone (267) 425-4666 in Philadelphia, Pennsylvania. Active studies at this site cover conditions such as Breast Cancer, Ovarian Cancer and Heart Failure. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Philadelphia
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Observational Approach Versus Surgical Intervention for Stones
for Nephrolithiasis
1 location in Philadelphia
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 6+
Code: NCT07718802·Not Yet Recruiting·Listed Jul 22, 2026
34 clinical trials at The Children's Hospital of Philadelphia
·Clear filters· Get a weekly email when new trials open in Philadelphia, PA.
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
for Dravet Syndrome
Sites in Philadelphia +20 more locations
Sponsor: Epygenix
Sex: All·Age: 2+
Code: NCT04462770·Phase 3·Recruiting·Listed Jul 2020
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
for Type 1 Diabetes Mellitus
Sites in Philadelphia +31 more locations
Sponsor: Sanofi
Sex: All·Age: 1 - 25
Code: NCT07088068·Phase 3·Recruiting·Listed Jul 2025
Registry for Stage 2 Type 1 Diabetes
for Type 1 Diabetes
Sites in Philadelphia +36 more locations
Sponsor: Sanofi
Sex: All·Age: All ages
Code: NCT06481904·Recruiting·Listed Jul 2024
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
for Ig-E Mediated Food Allergy
Drug: RPT904
Sites in Philadelphia, Pittsburgh +20 more locations
Sponsor: RAPT Therapeutics, Inc.
Sex: All·Age: 12 - 55
Code: NCT07220811·Phase 2·Recruiting·Listed Oct 2025
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
for Ulcerative Colitis
Drug: Risankizumab
Sites in Philadelphia, Pittsburgh +9 more locations
Sponsor: AbbVie
Sex: All·Age: 2 - 17
Code: NCT07071519·Phase 3·Recruiting·Listed Jul 2025
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
for Neutropenia
Sites in Philadelphia +20 more locations
Sponsor: X4 Pharmaceuticals
Sex: All·Age: 12+
Code: NCT06056297·Phase 3·Recruiting·Listed Sep 2023
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
for Type 1 Diabetes
Sites in Philadelphia, Pittsburgh +20 more locations
Sponsor: SAb Biotherapeutics, Inc.
Sex: All·Age: 5 - 40
Code: NCT07187531·Phase 2·Recruiting·Listed Sep 2025
Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age
for Hyperkalemia
Drug: patiromer
Sites in Philadelphia +10 more locations
Sponsor: Vifor Pharma, Inc.
Sex: All·Age: 0 - 11
Code: NCT05766839·Phase 2·Recruiting·Listed Mar 2023
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
for Primary Mitochondrial Disease
Sites in Philadelphia, Pittsburgh +18 more locations
Sponsor: Pharming Technologies B.V.
Sex: All·Age: 18+
Code: NCT05650229·Phase 2·Recruiting·Listed Dec 2022
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy
for Spinal Muscular Atrophy
Drug: Apitegromab
Sites in Philadelphia +13 more locations
Sponsor: Scholar Rock, Inc.
Sex: All·Age: Up to 2
Code: NCT07047144·Phase 2·Recruiting·Listed Jul 2025
Pharmacokinetics, Efficacy, and Safety of Encaleret in Pediatric Participants With Autosomal Dominant Hypocalcemia Type 1 (ADH1)
for Autosomal Dominant Hypocalcemia Type 1 (ADH1)
Sites in Philadelphia +3 more locations
Sponsor: Calcilytix Therapeutics, Inc., a BridgeBio company
Sex: All·Age: 0 - 17
Code: NCT07080385·Phase 2, Phase 3·Recruiting·Listed Jul 2025
Collaboration for Down Syndrome Progress (CDP)
for Down Syndrome
Sites in Philadelphia, Pittsburgh +14 more locations
Sponsor: RTI International
Sex: All·Age: All ages
Code: NCT07625579·Recruiting·Listed Jun 2026
A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
for Epileptic Encephalopathy
Sites in Philadelphia +4 more locations
Sponsor: Institut de Recherches Internationales Servier
Sex: All·Age: 2 - 12
Code: NCT07227857·Phase 1, Phase 2·Recruiting·Listed Nov 2025
Primary Sclerosing Cholangitis in Children
for Primary Sclerosing Cholangitis
Sites in Philadelphia +8 more locations
Sponsor: Arbor Research Collaborative for Health
Sex: All·Age: 2 - 25
Code: NCT04181138·Recruiting·Listed Nov 2019
Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients
for Autoimmune Lymphoproliferative Syndrome
Drug: Soquelitinib
Sites in Philadelphia +2 more locations
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Sex: All·Age: 16 - 120
Code: NCT06730126·Phase 2·Recruiting·Listed Dec 2024
BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia
for Endotracheal Extubation
Sites in Philadelphia +1 more location
Sponsor: Telethon Kids Institute
Sex: All·Age: 0 - 16
Code: NCT07204990·Recruiting·Listed Oct 2025
Home Apnea Testing in CHildren Trial
for Sleep Apnea, Obstructive
1 location in Philadelphia
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 5 - 12
Code: NCT05382754·Recruiting·Listed May 2022
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
for Chronic Kidney Disease
Sites in Philadelphia +1 more location
Sponsor: Johns Hopkins Bloomberg School of Public Health
Sex: All·Age: 6 Months - 22
Code: NCT00327860·Recruiting·Listed May 2006
Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH
for Developmental Dysplasia of the Hip
1 location in Philadelphia
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 4 Months - 24 Months
Code: NCT03107520·EARLY_Phase 1·Recruiting·Listed Apr 2017
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
for Mitochondrial Disorders
Sites in Philadelphia, Pittsburgh +14 more locations
Sponsor: Columbia University
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT01694940·Recruiting·Listed Sep 2012
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
for Failed or Difficult Intubation, Sequela
Sites in Philadelphia, Hershey +49 more locations
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: All ages
Code: NCT02493478·Recruiting·Listed Jul 2015
Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)
for Cystic Fibrosis (CF)
Sites in Philadelphia +17 more locations
Sponsor: Jaeb Center for Health Research
Sex: All·Age: 12+
Code: NCT06837181·Recruiting·Listed Feb 2025
The Myelin Disorders Biorepository Project
for Leukodystrophy
Sites in Philadelphia, Pittsburgh +21 more locations
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: All ages
Code: NCT03047369·Recruiting·Listed Feb 2017
Validation of Nanosensor Oxygen Measurement
for MItochondrial Myopathies
1 location in Philadelphia
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 18 - 65·Accepts healthy volunteers
Code: NCT06819683·Phase 1·Recruiting·Listed Feb 2025
Neurometabolic Profile of Individuals With Primary Mitochondrial Disease
for Primary Mitochondrial Disease
1 location in Philadelphia
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 8 - 75·Accepts healthy volunteers
Code: NCT06890520·Recruiting·Listed Mar 2025
Validation of Oxygen Nanosensor in Mitochondrial Myopathy
for Mitochondrial Myopathies
1 location in Philadelphia
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 18 - 65·Accepts healthy volunteers
Code: NCT04086329·Phase 1·Recruiting·Listed Sep 2019
STXBP1 and SYNGAP1 Related Disorders Natural History Study
for Genetic Disease
Sites in Philadelphia +4 more locations
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: All ages
Code: NCT06555965·Recruiting·Listed Aug 2024
The Pediatric Anesthesia Quality Improvement Project
for Surgery
Sites in Philadelphia, Hershey +35 more locations
Sponsor: The Society for Pediatric Anesthesia
Sex: All·Age: Up to 21
Code: NCT00674388·Recruiting·Listed May 2008
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
for Pulmonary Invasive Fungal Infections
Sites in Philadelphia +26 more locations
Sponsor: Arkansas Children's Hospital Research Institute
Sex: All·Age: 120 Days - 21
Code: NCT03827694·Recruiting·Listed Feb 2019
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
for Hypothalamic Obesity
Sites in Philadelphia +1 more location
Sponsor: Seattle Children's Hospital
Sex: All·Age: 6 - 28
Code: NCT06299891·Phase 2·Recruiting·Listed Mar 2024
Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy
for Eosinophilic Esophagitis (EoE)
1 location in Philadelphia
Sponsor: Children's Hospital of Philadelphia
Sex: All·Age: 7 - 17
Code: NCT06389994·Recruiting·Listed Apr 2024
SHAPE of Portal Hypertension in Children
for Hypertension, Portal
1 location in Philadelphia
Sponsor: Thomas Jefferson University
Sex: All·Age: 6 - 21
Code: NCT04720456·Phase 2·Recruiting·Listed Jan 2021
Common conditions studied in Philadelphia
- Breast Cancer (36 active studies)
- Cancer (25 active studies)
- Ovarian Cancer (22 active studies)
- Heart Failure (21 active studies)
- Prostate Cancer (21 active studies)
- Advanced Solid Tumor (18 active studies)
Leading research sponsors in Philadelphia
- University of Pennsylvania
- Abramson Cancer Center at Penn Medicine
- Children's Hospital of Philadelphia
- Thomas Jefferson University
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Philadelphia?
There are approximately 1,987 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Philadelphia pay participants?
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Philadelphia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Philadelphia?
The most common conditions under active study in Philadelphia include Breast Cancer (36), Cancer (25), Ovarian Cancer (22), Heart Failure (21), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Philadelphia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Philadelphia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Philadelphia?
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Philadelphia right now?
The largest active categories in Philadelphia are Cancer & tumors (557), Neurology & pain (111), Cardiovascular (110). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of The Children's Hospital of Philadelphia?
The Children's Hospital of Philadelphia is located at 34TH & CIVIC CENTER AVE, PHILADELPHIA, PA 19104. Use the Google Maps link in the intro above to get directions.
How do I contact The Children's Hospital of Philadelphia?
You can reach The Children's Hospital of Philadelphia by phone at (267) 425-4666. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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