Paid Clinical Trials in Sunnyvale, CA
As of August 2026, 36 paid clinical trials are recruiting in Sunnyvale, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Sunnyvale offers studies at sites including Palo Alto Medical Foundation-Sunnyvale for conditions such as Major Depressive Disorder, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Lung Non-Small Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Sunnyvale
Trials by drug in Sunnyvale
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33 clinical trials
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Galleri® in the Medicare Population.
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements
Prevention of Cervical Cancer Using the Genotyping Screening and Same-day Self-sampling
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
Quadriceps Strengthening ACL Reconstruction
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos
A Primary Care Based Intervention to Prevent Childhood Obesity Among Low-income Latino Children
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
Top Research Study Locations in Sunnyvale
Researchers run research studies in Sunnyvale, CA at 14 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Palo Alto Medical Foundation-Sunnyvale | Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | 20 |
| Acacia Clinics | Major Depressive Disorder, Bipolar Disorders, Depression | 4 |
| Acacia Research Center | PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder | 1 |
| Atila Biosystems, Inc. | Human Papilloma Virus | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Investigative | Hidradenitis Suppurativa (HS) | 1 |
| LGTC Group | Major Depressive Disorder | 1 |
| Palo Alto Medical Foundation - Sunnyvale Center | Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases | 1 |
| Palo Alto Medical Foundation Research Center | Breast Cancer | 1 |
| Stanford Fertility and Reproductive Medicine Center | Aneuploidy, Mosaicism, Pregnancy Outcome | 1 |
| Stanford Medicine Children's Health | ACL Tear | 1 |
| Sutter Palo Alto Medical Foundation: Sunnyvale | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Sutter Valley Hospitals PAMF Sunnyvale | Cancer | 1 |
| Valley Health Center Sunnyvale | Obesity, Childhood | 1 |
Active & Upcoming Studies in Sunnyvale (2026)
Recruiting trials in Sunnyvale grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (24 active studies)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
- Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial · Phase 3 · NRG Oncology
Mental health & behavior (4 active studies)
Diabetes & metabolic (1 active study)
- A Primary Care Based Intervention to Prevent Childhood Obesity Among Low-income Latino Children · University of California, San Francisco
Common conditions studied in Sunnyvale
- Major Depressive Disorder (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (2 active studies)
- Breast Cancer (2 active studies)
- Lung Non-Small Cell Carcinoma (2 active studies)
- Post-Traumatic Stress Disorder, PTSD (2 active studies)
- Recurrent Lung Non-Small Cell Carcinoma (2 active studies)
Leading research sponsors in Sunnyvale
- NRG Oncology
- SWOG Cancer Research Network
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- Kernel
Frequently asked questions
How many paid clinical trials are currently recruiting in Sunnyvale?
There are approximately 36 recruiting clinical trials in Sunnyvale, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Sunnyvale pay participants?
Most recruiting trials in Sunnyvale compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Sunnyvale?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Sunnyvale?
The most common conditions under active study in Sunnyvale include Major Depressive Disorder (4), Anatomic Stage II Breast Cancer AJCC v8 (2), Breast Cancer (2), Lung Non-Small Cell Carcinoma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Sunnyvale?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Sunnyvale on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Sunnyvale?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Sunnyvale?
Recruiting research sites in Sunnyvale include Palo Alto Medical Foundation-Sunnyvale, Acacia Clinics, Acacia Research Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Sunnyvale right now?
The largest active categories in Sunnyvale are Cancer & tumors (24), Mental health & behavior (4), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.