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Melanoma Clinical Trials in Worcester, MA
As of June 2026, 1 paid clinical trial is recruiting for Melanoma in Worcester, Massachusetts. Melanoma trials test immune checkpoint inhibitors, adoptive cell therapies, and BRAF/MEK targeted combinations in both early and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1 clinical trial for Melanoma
·Clear filters·↓ Download CSVAbout research studies in Worcester
Worcester has approximately 230 recruiting research studies across a wide range of therapeutic areas. Massachusetts is a global epicenter of biomedical research, anchored by Harvard-affiliated hospitals (MGH, Brigham and Women's, Dana-Farber), Boston Children's Hospital, and the Kendall Square biotech corridor in Cambridge.
Top Research Study Locations in Worcester
Researchers run research studies in Worcester, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Massachusetts Chan Medical School | Immune Thrombocytopenic Purpura (ITP), Rheumatoid Arthritis, Acute Stress Reaction | 33 |
| UMass Memorial Medical Center - University Campus | Stage IV Lung Cancer AJCC v8, B Acute Lymphoblastic Leukemia, Recurrent Lung Non-Small Cell Carcinoma | 28 |
| UMass Memorial Medical Center | Intracerebral Hemorrhage, Acute Kidney Injury, Atrial Fibrillation | 18 |
| UMass Chan Medical School | Atrial Fibrillation, AML With Mutated NPM1, ASCVD | 15 |
| University of Massachusetts Memorial Medical Center | Pregnancy, High Risk, B-cell Malignancy, Becker Muscular Dystrophy | 15 |
| University of Massachusetts | Abdominal Aortic Aneurysm, Acute Ischemic Stroke, Acute Lymphoblastic Leukemia (ALL) | 14 |
| University of Massachusetts Medical School | Multiple Sclerosis, Alcohol; Use, Problem, Amyotrophic Lateral Sclerosis | 9 |
| Vitalix Clinical | Major Depressive Disorder, Alzheimer Disease, Post Traumatic Stress Disorder | 4 |
| UMass Memorial Health | Clostridium Difficile Infection, Fecal Microbiota Transplantation, Fragile X Syndrome | 3 |
| University of Massachusetts Medical Center | Aortic Valve Disease, Aortic Valve Stenosis, COACH | 3 |
| GSK Investigational Site | Multiple Myeloma, Neoplasms, Head and Neck, Newly Diagnosed Multiple Myeloma | 2 |
| Local Institution - 0059 | Schizophrenia, Autism-Related Irritability | 2 |
| Reliant Medical Group | Asthma, Asthma Attack, Asthma Exacerbations | 2 |
| UMass Memorial Hospital | Genetic Predisposition to Disease, Genetics Disease, Genetics/Birth Defects | 2 |
| UMass/Shields | Esophageal Cancer, Gastric Cancer (GC), Gastroesophageal Junction | 2 |
| UMassMemorial Health Care | Fatigue, Shift Work Type Circadian Rhythm Sleep Disorder, Wellness, Psychological | 2 |
| University of Massachusetts Memorial Health | Lupus Nephritis, Neuropsychiatric Systemic Lupus Erythematosus, Postpartum Hypertension | 2 |
| University of Massachusetts Memorial Health Care | Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation | 2 |
| University of Massachusetts Worcester | GIST, Triple Negative Breast Cancer | 2 |
| University of Massachusetts, Worcester | Chronic Cutaneous Lupus Erythematosus, Moderately to Severely Active Crohn Disease, Subacute Cutaneous Lupus Erythematosus | 2 |
| Central Massachusetts Health Center | Alcohol-Related Disorders, Contraception, Maternal Health | 1 |
| Clinical Research Site #331 | Immunoglobulin A Nephropathy | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Decentralized | Adherence, Medication, Anticoagulants and Bleeding Disorders, Atrial Fibrillation | 1 |
| Family Health Center of Worcester | Depression, Diabetes, Hyperlipidemias | 1 |
Active & Upcoming Studies in Worcester (2026)
Recruiting trials in Worcester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (59 active studies)
- Facilitation of Information eXchange for Shared Decision Making for Lung Cancer Screening · University of Massachusetts, Worcester
- SafeHeal Colovac Anastomosis Protection Device Evaluation Pivotal Study · SafeHeal Inc
Neurology & pain (18 active studies)
- Social Media and Risk-reduction Training for Preterm Infant Care Practices · University of Massachusetts, Worcester
- Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts · University of Massachusetts, Worcester
Mental health & behavior (14 active studies)
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Cardiovascular (13 active studies)
- Social Needs Screening and Chronic Diseases Study (WE CARE) · University of Massachusetts, Worcester
- ELEVATE High-Risk PCI Pivotal Study · Magenta Medical Ltd.
Diabetes & metabolic (6 active studies)
- Food is Medicine in Pediatric Patients With Diabetes · University of Massachusetts, Worcester
- Social Needs Screening and Chronic Diseases Study (WE CARE) · University of Massachusetts, Worcester
Vaccines (5 active studies)
Pediatric (4 active studies)
- Social Media and Risk-reduction Training for Preterm Infant Care Practices · University of Massachusetts, Worcester
- Social Needs Screening and Chronic Diseases Study (WE CARE) · University of Massachusetts, Worcester
Eye & vision (3 active studies)
- The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma · EARLY_Phase 1 · MCPHS University
- Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD · Phase 3 · AbbVie
HIV / STI (1 active study)
Common conditions studied in Worcester
- Schizophrenia (6 active studies). Schizophrenia research tests muscarinic agonists, long-acting injectable antipsychotics, and cognitive remediation therapies.
- Stage IV Lung Cancer AJCC v8 (5 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Acute Myeloid Leukemia (4 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Atrial Fibrillation (4 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
- Major Depressive Disorder (4 active studies). Major depressive disorder research examines rapid-acting agents, augmentation strategies, and digital therapeutics for treatment-resistant cases.
- B Acute Lymphoblastic Leukemia (3 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
Leading research sponsors in Worcester
- University of Massachusetts, Worcester
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- Pfizer
Local regulations and guidelines
Clinical trials in Massachusetts are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Massachusetts trials follow additional state privacy requirements enforced under 201 CMR 17.00 and oversight from the Massachusetts Department of Public Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Worcester. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Worcester
Hipa.ai aggregates every recruiting study in Worcester from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Worcester?
There are approximately 230 recruiting clinical trials in Worcester, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Worcester pay participants?
Most recruiting trials in Worcester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Worcester?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Worcester?
The most common conditions under active study in Worcester include Schizophrenia (6), Stage IV Lung Cancer AJCC v8 (5), Acute Myeloid Leukemia (4), Atrial Fibrillation (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Worcester?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Worcester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Worcester?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Worcester?
Recruiting research sites in Worcester include University of Massachusetts Chan Medical School, UMass Memorial Medical Center - University Campus, UMass Memorial Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Worcester right now?
The largest active categories in Worcester are Cancer & tumors (59), Neurology & pain (18), Mental health & behavior (14). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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