Neighborhood Connect
for Built Environment
1 location in Worcester
Sponsor: University of Massachusetts, Worcester
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07780825·Recruiting·Listed Aug 24, 2026
Clinical Trials at University of Massachusetts Chan Medical School
As of August 2026, 24 paid clinical trials are recruiting at University of Massachusetts Chan Medical School, located at 55 LAKE AVE N, WORCESTER, MA 01655-0002, phone (508) 334-6587 in Worcester, Massachusetts. Active studies at this site cover conditions such as Schizophrenia, Major Depressive Disorder and Stage IV Lung Cancer AJCC v8. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Worcester
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
25 clinical trials at University of Massachusetts Chan Medical School
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A Study of Brenipatide in Adult Participants With Schizophrenia
for Schizophrenia
Drug: Brenipatide
Sites in Worcester, Watertown +30 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 55
Code: NCT07410507·Phase 2·Recruiting·Listed Feb 2026
A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia
for Severe Hypertriglyceridemia
Drug: Solbinsiran
Sites in Worcester +28 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07269210·Phase 2·Recruiting·Listed Dec 2025
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
for Ovarian Neoplasms
Sites in Worcester +87 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07213804·Phase 3·Recruiting·Listed Oct 2025
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
for Urothelial Carcinoma
Sites in Worcester +142 more locations
Sponsor: Seagen, a wholly owned subsidiary of Pfizer
Sex: All·Age: 18+
Code: NCT04879329·Phase 2·Recruiting·Listed May 2021
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
for COVID-19 SARS-CoV-2 Infection
Sites in Worcester, Boston +81 more locations
Sponsor: Pfizer
Sex: All·Age: 12+
Code: NCT06679140·Phase 3·Recruiting·Listed Nov 2024
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
for COVID-19 Infection
Sites in Worcester, Boston +64 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT07013474·Phase 3·Recruiting·Listed Jun 2025
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
for Colitis, Ulcerative
Sites in Worcester, Boston +16 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 2 - 17
Code: NCT05076175·Phase 2, Phase 3·Recruiting·Listed Oct 2021
A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)
for Multiple Myeloma
Drug: Elranatamab
Sites in Worcester, Newton +32 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT06215118·Phase 1·Recruiting·Listed Jan 2024
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
for Lyme Disease
Sites in Worcester +18 more locations
Sponsor: Pfizer
Sex: All·Age: 7+·Accepts healthy volunteers
Code: NCT07500506·Phase 3·Recruiting·Listed Mar 2026
A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
for Immune Thrombocytopenic Purpura (ITP)
Sites in Worcester, Boston +18 more locations
Sponsor: Takeda
Sex: All·Age: 18+
Code: NCT06948318·Phase 3·Recruiting·Listed Apr 2025
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
for Immune Thrombocytopenic Purpura (ITP)
Sites in Worcester, Boston +22 more locations
Sponsor: Takeda
Sex: All·Age: 18+
Code: NCT06722235·Phase 3·Recruiting·Listed Dec 2024
A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy
for Duchene Muscular Dystrophy
Drug: Givinostat
Sites in Worcester, Boston +7 more locations
Sponsor: ITF Therapeutics LLC
Sex: All·Age: 6+
Code: NCT07127978·Recruiting·Listed Aug 2025
Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery
for Injury of Ureter During Surgery (Disorder)
Sites in Worcester +4 more locations
Sponsor: Curadel Surgical Innovations, Inc.
Sex: All·Age: 18+
Code: NCT06101745·Phase 2, Phase 3·Recruiting·Listed Oct 2023
ARISe at UMass Chan
for Vaccination
1 location in Worcester
Sponsor: University of Massachusetts, Worcester
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07236034·Recruiting·Listed Nov 2025
RA-PRO PRAGMATIC TRIAL
for Rheumatoid Arthritis
Sites in Worcester, Boston +46 more locations
Sponsor: University of Alabama at Birmingham
Sex: All·Age: 18+
Code: NCT04692493·Phase 3·Recruiting·Listed Dec 2020
PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis
for Progressive Pulmonary Fibrosis
Sites in Worcester +6 more locations
Sponsor: University of Massachusetts, Worcester
Sex: All·Age: 18 - 80
Code: NCT06855329·Recruiting·Listed Mar 2025
Botulinum Toxin Therapy in Hidradenitis Suppurativa
for Hidradenitis Suppurativa
1 location in Worcester
Sponsor: University of Massachusetts, Worcester
Sex: All·Age: 18 - 75
Code: NCT05403710·Recruiting·Listed Jun 2022
Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application
for Epilepsy
Sites in Worcester +1 more location
Sponsor: Dartmouth-Hitchcock Medical Center
Sex: All·Age: 18+
Code: NCT06425029·Recruiting·Listed May 2024
Testimonials and Navigation in Rheumatology
for Rheumatologic Disease
Sites in Worcester, Boston +1 more location
Sponsor: University of Alabama at Birmingham
Sex: All·Age: 18+
Code: NCT06469788·Recruiting·Listed Jun 2024
Asthma Link Effectiveness Trial
for Childhood Asthma
1 location in Worcester
Sponsor: University of Massachusetts, Worcester
Sex: All·Age: 5 - 14
Code: NCT06388460·Recruiting·Listed Apr 2024
Promoting Improved Functioning Among People Experiencing Stressful Situations
for Acute Stress Reaction
Sites in Worcester +3 more locations
Sponsor: University of North Carolina, Chapel Hill
Sex: All·Age: 18 - 50
Code: NCT06482567·Recruiting·Listed Jul 2024
Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation
for COPD (Chronic Obstructive Pulmonary Disease)
1 location in Worcester
Sponsor: University of Massachusetts, Worcester
Sex: All·Age: 18+
Code: NCT07072039·Recruiting·Listed Jul 2025
Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
for Psoriatic Arthritis
Drug: Guselkumab
Sites in Worcester +13 more locations
Sponsor: University of Pennsylvania
Sex: All·Age: 18 - 80
Code: NCT05669833·Phase 3·Recruiting·Listed Jan 2023
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
for Generalized Myasthenia Gravis (gMG)
Sites in Worcester, Boston +15 more locations
Sponsor: Cabaletta Bio
Sex: All·Age: 18 - 70
Code: NCT06359041·Phase 1, Phase 2·Recruiting·Listed Apr 2024
Common conditions studied in Worcester
- Schizophrenia (5 active studies)
- Major Depressive Disorder (4 active studies)
- Stage IV Lung Cancer AJCC v8 (4 active studies)
- Acute Myeloid Leukemia (3 active studies)
- Atrial Fibrillation (3 active studies)
- B Acute Lymphoblastic Leukemia (3 active studies)
Leading research sponsors in Worcester
- University of Massachusetts, Worcester
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Worcester?
There are approximately 208 recruiting clinical trials in Worcester, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Worcester pay participants?
Most recruiting trials in Worcester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Worcester?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Worcester?
The most common conditions under active study in Worcester include Schizophrenia (5), Major Depressive Disorder (4), Stage IV Lung Cancer AJCC v8 (4), Acute Myeloid Leukemia (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Worcester?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Worcester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Worcester?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Worcester?
Recruiting research sites in Worcester include University of Massachusetts Chan Medical School, UMass Memorial Medical Center - University Campus, UMass Memorial Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Worcester right now?
The largest active categories in Worcester are Cancer & tumors (53), Mental health & behavior (14), Neurology & pain (14). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of Massachusetts Chan Medical School?
University of Massachusetts Chan Medical School is located at 55 LAKE AVE N, WORCESTER, MA 01655-0002. Use the Google Maps link in the intro above to get directions.
How do I contact University of Massachusetts Chan Medical School?
You can reach University of Massachusetts Chan Medical School by phone at (508) 334-6587. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
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