Coronary artery disease Clinical Trials

Recruiting coronary artery disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat coronary artery disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting coronary artery disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting coronary artery disease trials

Within

OPTIA-AF Trial: Rhythm-Guided Antithrombotic Strategy After AF Ablation

for Atrial Fibrillation (AF)

Sponsor: Ewha Womans University Mokdong Hospital

Sex: All·Age: 18+

Code: NCT07496281·Phase 4

Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation

for Coronary Artery Disease

1 site in Little Rock

Sponsor: Central Arkansas Veterans Healthcare System

Sex: All·Age: 19+

Code: NCT01952873

Nursing Intervention for Adaptation After Myocardial Revascularization

for Coronary Artery Disease

Sponsor: Universidad de la Sabana

Sex: All·Age: 18+

Code: NCT07576569

Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease

for Coronary Artery Disease

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06253884

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

for Heart Failure

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT05377320

PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF

for Heart Failure With Reduced Ejection Fraction

Sponsor: Nanjing First Hospital, Nanjing Medical University

Sex: All·Age: 18+

Code: NCT07349979

Health Coaching for Patients With Cardiovascular Disease

for Congestive Heart Failure Treated

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06904144

Flecainide Safety in Patients With Coronary Artery Disease and Atrial Fibrillation

for Atrial Fibrillation (AF)

Sponsor: Universitaire Ziekenhuizen KU Leuven

Sex: All·Age: 18+

Code: NCT07405671·Phase 4

Comparative Outcomes of Mammary Artery Harvesting: Infection, Occlusion Rates and Thoracic Pain Assessment

for Coronary Artery Disease

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT07720661

Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.

for Coronary Artery Disease

Sponsor: Federal University of São Paulo

Sex: All·Age: 18 - 75

Code: NCT07699679

Quantitative Myocardial Perfusion Imaging Assessment by SPECT/CT

for Coronary Artery Disease

Sponsor: Centre Hospitalier Régional d'Orléans

Sex: All·Age: 18+

Code: NCT07708805

Needle Free Assessment of Myocardial Oxygenation in Healthy Subjects

for Coronary Artery Disease

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT06000540

Total Arterial vs. Mixed Grafting in Left Coronary CABG

for Coronary Artery Disease

Sponsor: Second Hospital of Jilin University

Sex: All·Age: 18 - 80

Code: NCT07057713

Silicon-based Photon Counting Computed Tomography for Advanced Cardiac Imaging

for Coronary Artery Disease

Sponsor: Ronny R Buechel, MD

Sex: All·Age: 18+

Code: NCT07411196

Intraoperative Portable Ultrasound for Real-Time Graft Perfusion Assessment During CABG: A Randomized Controlled Trial

for Coronary Artery Disease

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: 18+

Code: NCT07700524

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

for Atherosclerosis

12 sites incl. Huntsville

Sponsor: Beijing Inno Medicine Co., Ltd.

Sex: All·Age: 18 - 80

Code: NCT07521007·Phase 2

PREventive Invasive Strategy for Obstructive Coronary Artery Disease With Vulnerable Plaque Evaluated by CoroNary Computed Tomography Angiography-2

for Coronary Artery Disease

Sponsor: Seung-Jung Park

Sex: All·Age: 18+

Code: NCT07569692

The Prospective, Multicenter, Randomized Controlled Trial of the VentriCure Interventional Left Ventricular Assist System

for Coronary Artery Disease

Sponsor: Life Shield Medical Technology Co., LTD

Sex: All·Age: 18+

Code: NCT07675005

CPB and Aortic Cross-Clamp Durations and ICU Length of Stay After CABG Retrospective Observational Cohort Study

for Coronary Artery Disease

Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Sex: All·Age: 18+

Code: NCT07711951

Apply to this trial

The HYCORE1 Trial: Hybrid Revascularization Versus Coronary Artery Bypass Grafting

for Coronary Artery Disease

Sponsor: Rigshospitalet, Denmark

Sex: All·Age: 18 - 80

Code: NCT05504031

Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention

for Coronary Artery Disease

1 site in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 22+

Code: NCT07691502

Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease

for Cardiorenal Metabolic Syndrome

Sponsor: Peking University Third Hospital

Sex: All·Age: 18+

Code: NCT07704190·Phase 4

STRATegy SUccesS in High-Risk PCI With Impella CP: Evaluation of Hemodynamic Protection in Complex PCI

for Coronary Artery Disease

Sponsor: Rayyan Hemetsberger

Sex: All·Age: 18+

Code: NCT07588399

Baduanjin Intervention in Clinical Studies After Coronary Revascularization Surgery

for Percutaneous Coronary Intervention

Sponsor: Liu Qiang

Sex: All·Age: 18 - 80

Code: NCT07607951

Establishment of Disease Characteristics and a Chinese Medicine Prognosis Risk Model Based on a Large-Scale Database After Coronary Revascularization

for Coronary Artery Disease

Sponsor: Liu Qiang

Sex: All·Age: 18+

Code: NCT07613060

Clinical Study of Chinese Herbal Compound Qidan Xiaoke Granules in Patients After Coronary Revascularization

for Percutaneous Coronary Intervention

Sponsor: Liu Qiang

Sex: All·Age: 18 - 80

Code: NCT07616544·Phase 3

Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study

for Myocardial Injury

Sponsor: Second Hospital of Jilin University

Sex: All·Age: 21 - 80

Code: NCT07650487

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

for Coronary Artery Disease

17 sites incl. Phoenix

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07559903

Apply to this trial

Polymer-free Sirolimus Eluting Stent: Real-world Investigation of Safety and Outcomes

for Coronary Artery Disease

Sponsor: Dorian Garin

Sex: All·Age: 18+

Code: NCT07563231

A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery

for Coronary Artery Disease

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 40+

Code: NCT07570940·Phase 4

High-Intensity Interval Training vs Moderate-Intensity Continuous Training in Phase II Cardiac Rehabilitation

for Coronary Artery Disease

Sponsor: Riphah International University

Sex: All·Age: 18 - 60

Code: NCT07619664

Construction of a Prospective Cohort Database for the Perioperative Period of Cardiac Surgery

for Valve Heart Disease

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All·Age: All ages

Code: NCT07662317

Apply to this trial

Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers

for Coronary Artery Disease

Sponsor: Jung-min Ahn

Sex: All·Age: 19+

Code: NCT07566091

Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions

for Coronary Disease

1 site in Washington D.C.

Sponsor: Teleflex

Sex: All·Age: 18 - 80

Code: NCT07258290

Apply to this trial

QFR-Guided Virtual Stenting for Preprocedural Physiological Optimization of Percutaneous Coronary Intervention: A Randomized Controlled Trial

for Coronary Artery Disease

Sponsor: China National Center for Cardiovascular Diseases

Sex: All·Age: 18+

Code: NCT07635407

Apply to this trial

The PICCOLETO XI A-PREP Study

for In-Stent Coronary Artery Restenosis

Sponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETS

Sex: All·Age: 18+

Code: NCT07391033

CABG-AI-Supported Discharge Education

for Coronary Artery Disease

Sponsor: Hasan Kalyoncu University

Sex: All·Age: 18+

Code: NCT07503678

CHIP-CC Registry: A Prospective Multicenter Registry of Complex High-Risk PCI in China

for Coronary Artery Disease

Sponsor: Guofeng Gao

Sex: All·Age: 18 - 90

Code: NCT07557238

Clinical Information System Impact on Hospitalized Patients With Chronic Disease

for Diabete Mellitus

Sponsor: University of Calgary

Sex: All·Age: 18+

Code: NCT07609381

Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)

for Coronary Artery Disease

Sponsor: University Medical Center Groningen

Sex: All·Age: 18+

Code: NCT07269366

Apply to this trial

CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry

for Psoriatic Arthritis

Sponsor: JULIO GRANADOS MONTIEL

Sex: All·Age: 18+

Code: NCT07567378

1 or 6 Months of Dual Antiplatelet Therapy After Drug-coated Balloon Angioplasty for De-novo Small Coronary Artery Disease

for Stable Angina Pectoris

Sponsor: Daejeon St. Mary's hospital

Sex: All·Age: 19+

Code: NCT07592507·Phase 4

Measuring Athlete's Risk of Cardiovascular Events 3 (MARC-3)

for Coronary Artery Disease

Sponsor: Radboud University Medical Center

Sex: Male·Age: 45+

Code: NCT07625488

Effects of Icosapent Ethyl on Coronary Plaque, Inflammation, and Ventricular Remodeling

for Acute Coronary Syndromes (ACS)

Sponsor: Ruijin Hospital

Sex: All·Age: 18+

Code: NCT07641257

CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS

for Coronary

Sponsor: West China Hospital

Sex: All·Age: 40 - 75

Code: NCT07612774·Phase 4

Apply to this trial

Radial Access Data in Vascular Interventions Registry

for Radial Artery Occlusion

Sponsor: Mersin Medicalpark Hastanesi

Sex: All·Age: 18+

Code: NCT07614386

Apply to this trial

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

19 sites incl. Loma Linda

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744

Apply to this trial

Hybrid Group Singing

for Coronary Artery Disease

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 55 - 89

Code: NCT07355192

Apply to this trial

Impact of Hyperemic State on Angio-IMR Performance

for Coronary Artery Disease

Sponsor: Shanghai Zhongshan Hospital

Sex: All·Age: 18+

Code: NCT07613996

Apply to this trial

Correlation of FFR CT With Invasive FFR in Multi-ethnic Cohort- a Retrospective Study

for Coronary Artery Disease

Sponsor: Sandwell & West Birmingham Hospitals NHS Trust

Sex: All·Age: 18+

Code: NCT06790836

Apply to this trial

Ticagrelor-Based Dual Antiplatelet Therapy Duration in CABG

for Coronary Artery Disease

Sponsor: Kexiang Liu, MD

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06981390

Cardiovascular Acoustics for Early Disease Detection

for Valvular Heart Disease

Sponsor: Cambridge University Hospitals NHS Foundation Trust

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07496775

Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Controlled Trial

for Coronary Artery Disease

Sponsor: Montreal Heart Institute

Sex: All·Age: 40+

Code: NCT07524335·Phase 3

Electronic Letters to Improve Patient Activation in IHD: The NUDGE-IHD Trial

for Coronary Artery Disease

Sponsor: Tor Biering-Sørensen

Sex: All·Age: 18 - 85

Code: NCT07382414

Effects of Fecal Microbiota Transplantation in Patients With Type 2 Diabetes and Coronary Artery Disease (CAD-Microbiome) - A Pilot Study

for Coronary Artery Disease

Sponsor: University of Zurich

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07421947

A Coronary Computed Tomography Angiography-guided Intervention for High Risk Cardiovascular Disease Population in Rural China

for Coronary Artery Disease

Sponsor: Harbin Medical University

Sex: All·Age: 40 - 75

Code: NCT07416344

Strategic Comparison Of Ischemia-based Versus Plaque Burden and vulnErability-based Revascularization in High-Risk Coronary Artery Disease Patients

for Coronary Artery Disease

Sponsor: Bon-Kwon Koo

Sex: All·Age: 19+

Code: NCT07324720

Apply to this trial

Stents Versus PAclitaxel Coated Balloons for Revascularization of CompleX and Small Coronary Vessels (SPARX) Trial

for Coronary Artery Disease

Sponsor: Translumina GmbH

Sex: All·Age: 18+

Code: NCT07397845

Apply to this trial

Predictive Role of Photon Counting Computed Tomography in Acute Coronary Syndrom Patients

for Coronary Artery Disease

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18+

Code: NCT07536607

Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.

for Coronary Artery Disease

Sponsor: Cardiocentro Ticino

Sex: All·Age: 18+

Code: NCT07582835·Phase 3

Apply to this trial

Coronary artery disease clinical trials — common questions

Are coronary artery disease clinical trials free to join?

Yes. Participating in a coronary artery disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a coronary artery disease clinical trial?

Each coronary artery disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a coronary artery disease trial near me?

Use the location controls above. We'll show recruiting coronary artery disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many coronary artery disease trials are recruiting right now?

We're currently tracking roughly 78 recruiting coronary artery disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Coronary artery disease trials by city

Birmingham, AL Boston, MA Jacksonville, FL Los Angeles, CA Indianapolis, IN Glendale, CA Huntsville, AL Milwaukee, WI Oklahoma City, OK Sacramento, CA

Related specialties

Cardiology Heart disease