Coronary artery disease Clinical Trials

Recruiting coronary artery disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat coronary artery disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting coronary artery disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting coronary artery disease trials

Within

OPTIA-AF Trial: Rhythm-Guided Antithrombotic Strategy After AF Ablation

for Atrial Fibrillation (AF)

Sponsor: Ewha Womans University Mokdong Hospital

Sex: All·Age: 18+

Code: NCT07496281·Phase 4

Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation

for Coronary Artery Disease

1 site in Little Rock

Sponsor: Central Arkansas Veterans Healthcare System

Sex: All·Age: 19+

Code: NCT01952873

Nursing Intervention for Adaptation After Myocardial Revascularization

for Coronary Artery Disease

Sponsor: Universidad de la Sabana

Sex: All·Age: 18+

Code: NCT07576569

Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease

for Coronary Artery Disease

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06253884

Intraoperative Ultrasound Assessment of Coronary Artery and Bypass Graft Blood Flow During CABG

for Coronary Artery Disease

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: 18+

Code: NCT07700524

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

for Heart Failure

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT05377320

PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF

for Heart Failure With Reduced Ejection Fraction

Sponsor: Nanjing First Hospital, Nanjing Medical University

Sex: All·Age: 18+

Code: NCT07349979

Oral Versus Intravenous Tranexamic Acid in Off-Pump Coronary Artery Bypass Surgery

for Coronary Artery Disease

Sponsor: Clinique Saint-Luc

Sex: All·Age: 18+

Code: NCT07740330·Phase 4

Intraoperative Targeted Versus Liberal Blood Pressure Management in Patients Undergoing Off-pump Coronary Artery Bypass Grafting

for Coronary Artery Disease

Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital

Sex: All·Age: 18+

Code: NCT07787364

Health Coaching for Patients With Cardiovascular Disease

for Congestive Heart Failure Treated

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06904144

Erector Spinae Oxygen Saturation and AKI After OPCAB

for Acute Kidney Injury

Sponsor: Yonsei University

Sex: All·Age: 19+

Code: NCT07760129

Flecainide Safety in Patients With Coronary Artery Disease and Atrial Fibrillation

for Atrial Fibrillation (AF)

Sponsor: Universitaire Ziekenhuizen KU Leuven

Sex: All·Age: 18+

Code: NCT07405671·Phase 4

Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG)

for Coronary Artery Disease

Sponsor: Humacyte, Inc.

Sex: All·Age: 18+

Code: NCT07730528·Phase 2

Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail Patients

for Frailty

Sponsor: University of Sao Paulo General Hospital

Sex: All·Age: 60+

Code: NCT07742475

Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid Prolonged-Release Capsules) Effects in Adult Patients With Iron Deficiency Anemia and Cardiovascular Disease

for Iron Deficiency Anemia

Sponsor: Alcea

Sex: All·Age: 18+

Code: NCT07753031

Sedentary Behavior Intervention for Older Adults With Coronary Heart Disease and Frailty

for Coronary Artery Disease

Sponsor: Gansu University of Chinese Medicine

Sex: All·Age: 60+

Code: NCT07762898

Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and Diaphragm Function

for Coronary Artery Disease

Sponsor: Koşuyolu Kartal Heart Training and Research Hospital

Sex: All·Age: 18+

Code: NCT07800741

Effect of Eye Mask Use on Sleep Quality and Delirium After CABG Surgery

for Coronary Artery Disease

Sponsor: Munzur University

Sex: All·Age: 18+

Code: NCT07768020

A Physical Activity Programme Focussed on Step Volume and Intensity for People With Cardiovascular Disease: Getting Active and Staying Active After Cardiac Rehabilitation

for Coronary Artery Disease

Sponsor: Radboud University Medical Center

Sex: All·Age: 18+

Code: NCT07723274

Rapid or Ultra-rapid Diagnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin on Hospital Presentation

for Coronary Syndrome, Acute

Sponsor: Herlev and Gentofte Hospital

Sex: All·Age: 18+

Code: NCT07727135

Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients

for ST-elevation Myocardial Infarction (STEMI)

Sponsor: Rehman Medical Institute - RMI

Sex: All·Age: 18 - 75

Code: NCT07749014·Phase 2

Impact of Procedural Factors on Drug-Coated Balloon Outcomes in Coronary Artery Disease

for PCI

Sponsor: Nanjing First Hospital, Nanjing Medical University

Sex: All·Age: 18 - 80

Code: NCT07764094

Apply to this trial

Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention

for Coronary Artery Disease

1 site in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 22+

Code: NCT07691502

Apply to this trial

Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.

for Coronary Artery Disease

Sponsor: Federal University of São Paulo

Sex: All·Age: 18 - 75

Code: NCT07699679

A Prospective Multicenter Real-World Registry of Quantitative Flow Ratio-Guided Coronary REvascularization and QuAlity evaLuation

for Coronary Artery Disease

Sponsor: China National Center for Cardiovascular Diseases

Sex: All·Age: 18+

Code: NCT07766434

Quantitative Myocardial Perfusion Imaging Assessment by SPECT/CT

for Coronary Artery Disease

Sponsor: Centre Hospitalier Régional d'Orléans

Sex: All·Age: 18+

Code: NCT07708805

Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management

for Coronary Artery Disease

Sponsor: Jiangsu Taizhou People's Hospital

Sex: All·Age: 18 - 65

Code: NCT07740044

CCTA-Based vs CAG-Based CABG: A Multicenter Pragmatic Non-Inferiority Trial

for Coronary Artery Disease

Sponsor: Ruijin Hospital

Sex: All·Age: 18+

Code: NCT07769008

Apply to this trial

Needle Free Assessment of Myocardial Oxygenation in Healthy Subjects

for Coronary Artery Disease

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT06000540

Total Arterial vs. Mixed Grafting in Left Coronary CABG

for Coronary Artery Disease

Sponsor: Second Hospital of Jilin University

Sex: All·Age: 18 - 80

Code: NCT07057713

Silicon-based Photon Counting Computed Tomography for Advanced Cardiac Imaging

for Coronary Artery Disease

Sponsor: Ronny R Buechel, MD

Sex: All·Age: 18+

Code: NCT07411196

Icosapent Ethyl for High-Risk Coronary Plaques Assessed by 18F-NaF PET/CT

for Coronary Artery Disease

Sponsor: China National Center for Cardiovascular Diseases

Sex: All·Age: 18 - 75

Code: NCT07762755·Phase 4

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

for Atherosclerosis

12 sites incl. Huntsville

Sponsor: Beijing Inno Medicine Co., Ltd.

Sex: All·Age: 18 - 80

Code: NCT07521007·Phase 2

Apply to this trial

Progression, Management, and Clinical Outcomes of Coronary Artery Aneurysms

for Coronary Artery Disease

Sponsor: Nanjing First Hospital, Nanjing Medical University

Sex: All·Age: 18 - 80

Code: NCT07764081

Apply to this trial

PREventive Invasive Strategy for Obstructive Coronary Artery Disease With Vulnerable Plaque Evaluated by CoroNary Computed Tomography Angiography-2

for Coronary Artery Disease

Sponsor: Seung-Jung Park

Sex: All·Age: 18+

Code: NCT07569692

The Prospective, Multicenter, Randomized Controlled Trial of the VentriCure Interventional Left Ventricular Assist System

for Coronary Artery Disease

Sponsor: Life Shield Medical Technology Co., LTD

Sex: All·Age: 18+

Code: NCT07675005

Turkish Chronic Total Occlusion Percutaneous Coronary Intervention Registry

for Chronic Total Occlusion (CTO)

Sponsor: Ahmet Seyfeddin Gürbüz

Sex: All·Age: 18+

Code: NCT07761624

The HYCORE1 Trial: Hybrid Revascularization Versus Coronary Artery Bypass Grafting

for Coronary Artery Disease

Sponsor: Rigshospitalet, Denmark

Sex: All·Age: 18 - 80

Code: NCT05504031

Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease

for Cardiorenal Metabolic Syndrome

Sponsor: Peking University Third Hospital

Sex: All·Age: 18+

Code: NCT07704190·Phase 4

HeartMate App-Based Remote Monitoring for Cardiovascular Risk Factor Management

for Cardiovascular Diseases

Sponsor: Yonsei University

Sex: All·Age: 19+

Code: NCT07721584

STRATegy SUccesS in High-Risk PCI With Impella CP: Evaluation of Hemodynamic Protection in Complex PCI

for Coronary Artery Disease

Sponsor: Rayyan Hemetsberger

Sex: All·Age: 18+

Code: NCT07588399

Baduanjin Intervention in Clinical Studies After Coronary Revascularization Surgery

for Percutaneous Coronary Intervention

Sponsor: Liu Qiang

Sex: All·Age: 18 - 80

Code: NCT07607951

Establishment of Disease Characteristics and a Chinese Medicine Prognosis Risk Model Based on a Large-Scale Database After Coronary Revascularization

for Coronary Artery Disease

Sponsor: Liu Qiang

Sex: All·Age: 18+

Code: NCT07613060

Clinical Study of Chinese Herbal Compound Qidan Xiaoke Granules in Patients After Coronary Revascularization

for Percutaneous Coronary Intervention

Sponsor: Liu Qiang

Sex: All·Age: 18 - 80

Code: NCT07616544·Phase 3

Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study

for Myocardial Injury

Sponsor: Second Hospital of Jilin University

Sex: All·Age: 21 - 80

Code: NCT07650487

Effect of High-Intensity Interval Training Versus Home-Based Rehabilitation Program On Patients Underwent Coronary Artery Bypass Graft Surgery

for Coronary Artery Disease

Sponsor: Kafrelsheikh University

Sex: All·Age: 55 - 58

Code: NCT07775742

Apply to this trial

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

for Coronary Artery Disease

17 sites incl. Phoenix

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07559903

Apply to this trial

Polymer-free Sirolimus Eluting Stent: Real-world Investigation of Safety and Outcomes

for Coronary Artery Disease

Sponsor: Dorian Garin

Sex: All·Age: 18+

Code: NCT07563231

A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery

for Coronary Artery Disease

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 40+

Code: NCT07570940·Phase 4

High-Intensity Interval Training vs Moderate-Intensity Continuous Training in Phase II Cardiac Rehabilitation

for Coronary Artery Disease

Sponsor: Riphah International University

Sex: All·Age: 18 - 60

Code: NCT07619664

Cold-Region Exposure and Cardiac Remodeling After PCI

for Coronary Artery Disease

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18 - 80

Code: NCT07773870

Apply to this trial

Construction of a Prospective Cohort Database for the Perioperative Period of Cardiac Surgery

for Valve Heart Disease

Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine

Sex: All·Age: All ages

Code: NCT07662317

Apply to this trial

Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers

for Coronary Artery Disease

Sponsor: Jung-min Ahn

Sex: All·Age: 19+

Code: NCT07566091

Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions

for Coronary Disease

2 sites incl. Washington D.C.

Sponsor: Teleflex

Sex: All·Age: 18 - 80

Code: NCT07258290

Apply to this trial

HEMOSTATİC PAD AND SANDBAG

for Coronary Artery Disease

Sponsor: Uludag University

Sex: All·Age: 18+

Code: NCT07771127

Apply to this trial

QFR-Guided Virtual Stenting for Preprocedural Physiological Optimization of Percutaneous Coronary Intervention: A Randomized Controlled Trial

for Coronary Artery Disease

Sponsor: China National Center for Cardiovascular Diseases

Sex: All·Age: 18+

Code: NCT07635407

Apply to this trial

The PICCOLETO XI A-PREP Study

for In-Stent Coronary Artery Restenosis

Sponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETS

Sex: All·Age: 18+

Code: NCT07391033

CABG-AI-Supported Discharge Education

for Coronary Artery Disease

Sponsor: Hasan Kalyoncu University

Sex: All·Age: 18+

Code: NCT07503678

CHIP-CC Registry: A Prospective Multicenter Registry of Complex High-Risk PCI in China

for Coronary Artery Disease

Sponsor: Guofeng Gao

Sex: All·Age: 18 - 90

Code: NCT07557238

Clinical Information System Impact on Hospitalized Patients With Chronic Disease

for Diabete Mellitus

Sponsor: University of Calgary

Sex: All·Age: 18+

Code: NCT07609381

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Coronary artery disease clinical trials — common questions

Are coronary artery disease clinical trials free to join?

Yes. Participating in a coronary artery disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a coronary artery disease clinical trial?

Each coronary artery disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a coronary artery disease trial near me?

Use the location controls above. We'll show recruiting coronary artery disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many coronary artery disease trials are recruiting right now?

We're currently tracking roughly 78 recruiting coronary artery disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Coronary artery disease trials by city

Birmingham, AL Boston, MA Jacksonville, FL Los Angeles, CA Indianapolis, IN Glendale, CA Huntsville, AL Little Rock, AR Milwaukee, WI Oklahoma City, OK Sacramento, CA

Related specialties

Cardiology Heart disease