Acute kidney injury Clinical Trials

Recruiting acute kidney injury studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat acute kidney injury. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting acute kidney injury studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting acute kidney injury trials

Within

Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness

for Acute Kidney Injury

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07291778

Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial

for Acute Kidney Injury

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07604662

Amino Acid Infusion in Cardiac Surgery

for Acute Kidney Injury

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT07030933·Phase 4

Treatment Costs of Kidney Injury in Patients Having Heart Surgery in the UK

for Acute Kidney Injury

Sponsor: The Royal Wolverhampton Hospitals NHS Trust

Sex: All·Age: 18+

Code: NCT07719569

Early Biomarker Kidney Injury Assessment After Acumen Directed Fluid Management in Cardiac Surgery

for Renal Injury

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06109714

Early Kidney Injury Biomarkers in Gynecologic Laparoscopic Surgery

for Acute Kidney Injury

Sponsor: Medipol University

Sex: Female·Age: 18+

Code: NCT07704242

Analysis of Continuous Kidney Replacement Therapy (CKRT) Treatments With multiFlux Hemofilters Using Regional Citrate Anticoagulation (RCA) or Systemic Heparin Anticoagulation

for Acute Kidney Injury

Sponsor: Fresenius Medical Care Deutschland GmbH

Sex: All·Age: 1+

Code: NCT07679568

Early Postoperative L-arginine and Acute Kidney Injury After Cardiac Surgery

for Acute Kidney Injury

Sponsor: Xijing Hospital

Sex: All·Age: 18+

Code: NCT07718373

Infliximab for Immune Checkpoint Inhibitor Associated AKI

for Acute Kidney Injury

3 sites in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07683975·Phase 4

Volume Removal Intolerance During Net Ultrafiltration in Acute Kidney Injury Patients

for Acute Kidney Injury

Sponsor: Hospital Las Higueras

Sex: All·Age: 18+

Code: NCT07643597

Apply to this trial

Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy

for Acute Kidney Injury

1 site in Cincinnati

Sponsor: Dana Fuhrman

Sex: All·Age: Up to 18

Code: NCT07212595·Phase 2

Insights Into the Continuous Renal Replacement Therapy to Critical Ill Patients

for Continuous Renal Replacement Therapy (CRRT)

Sponsor: University of Alberta

Sex: All·Age: All ages

Code: NCT07365111

The Effect of Standard vs. Shorter Filter Lifespan During Continuous Renal Replacement Therapy

for Acute Kidney Injury

Sponsor: Universität Münster

Sex: All·Age: 18+

Code: NCT07630220

Remimazolam on the Incidence of Postoperative Acute Kidney Injury

for Remimazolam

Sponsor: Seoul National University Bundang Hospital

Sex: All·Age: 19 - 85

Code: NCT07674719

Nafamostat Mesylate Versus Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy in Sepsis-Associated Acute Kidney Injury

for Sepsis

Sponsor: Jianfeng Xie

Sex: All·Age: 18 - 90

Code: NCT07518303·Phase 4

Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury

for Acute Kidney Injury

Sponsor: Centre Hospitalier Universitaire de Nīmes

Sex: All·Age: 18+

Code: NCT07236463·Phase 1, Phase 2

Apply to this trial

The Vancomycin Piperacillin/Tazobactam (VPT) Patient Safety Trial (VPS)

for Infection

1 site in Cooperstown

Sponsor: Bassett Healthcare

Sex: All·Age: 18+

Code: NCT07556107·Phase 4

COordiNated CommuNication, Education, and Care Transitions After Acute Kidney Injury (CONNECT-AKI)- A Pilot Randomized Controlled Trial

for Acute Kidney Injury

Sponsor: Northwell Health

Sex: All·Age: 18+

Code: NCT07626268

Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury

for Acute Kidney Injury

Sponsor: Universität Münster

Sex: All·Age: 18+

Code: NCT07464431·Phase 4

FST Analysis Supporting Timely Therapy and Risk Assessment Via Clinical Decision Support for Kids

for Acute Kidney Injury

1 site in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT07718464

Apply to this trial

Acute Kidney Injury in Upper GI Bleeding Patients

for Upper Gastrointestinal Bleeding

Sponsor: Sohag University

Sex: All·Age: 18+

Code: NCT07636083

Initial Drainage Method and Flexible Ureteroscopy Outcomes in Calculous Anuria

for Calculous Anuria

Sponsor: Beni-Suef University

Sex: All·Age: 18+

Code: NCT07627880

Apply to this trial

Phosphate-Containing Replacement Fluid for Patients Undergoing CRRT

for Acute Kidney Injury

Sponsor: Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07550894·Phase 3

Acute Kidney Injury in Critically Ill Patients

for Acute Kidney Injury

Sponsor: Beijing Chao Yang Hospital

Sex: All·Age: 18+

Code: NCT07653321

Transcutaneous Auricular Vagus Nerve Stimulation for Preventing Acute Kidney Injury in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass

for Acute Kidney Injury

Sponsor: Sir Run Run Shaw Hospital

Sex: All·Age: 18+

Code: NCT07549243

Early Co-Administration of Crystalloid Fluid and Norepinephrine for Preventing Acute Kidney Injury in Septic Shock

for Septic Shock

Sponsor: Universitas Sumatera Utara

Sex: All·Age: 18+

Code: NCT07418541

Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment

for Acute Ischemic Stroke

Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Sex: All·Age: 18 - 100

Code: NCT07546448

Acute Kidney Injury In Care Transitions (ACT): Pragmatic Clinical Trial

for Acute Kidney Injury

3 sites incl. Mankato

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07670520

Apply to this trial

Correlation Between Preoperative Sleep and Postoperative Brain and Renal Dysfunction

for Postoperative Delirium

Sponsor: Xijing Hospital

Sex: All·Age: 18+

Code: NCT07518992

Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria

for Acute Calculous Anuria

Sponsor: Beni-Suef University

Sex: All·Age: 18+

Code: NCT07617948·Phase 2

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Study of the Relaxin Agonist R2R01 in Patients at High Risk for Cardiac Surgery Associated- Acute Kidney Injury

for Acute Kidney Injury

Sponsor: River 2 Renal Corp.

Sex: All·Age: 18+

Code: NCT07625553·Phase 2

Apply to this trial

MULTIMODAL APPROACH IN THE DIAGNOSIS OF SEPTIC AKI

for Acute Kidney Injury

Sponsor: Ankara Etlik City Hospital

Sex: All·Age: 18+

Code: NCT07472452

Peri-procedural Hydration to Prevent Acute Kidney Injury After Pulsed Field Ablation for Atrial Fibrillation

for Atrial Fibrillation (AF)

Sponsor: Beijing Anzhen Hospital

Sex: All·Age: 18+

Code: NCT07490808

Apply to this trial

Feasibility of Intradialytic Monitoring During CKRT

for Acute Kidney Injury

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07428395

Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat

for Acute Kidney Injury

1 site in Cedar Falls

Sponsor: University of Northern Iowa

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07472426

Apply to this trial

Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

for Acute Kidney Injury

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06840210

Apply to this trial

Is There Any Prognostic Value of Serum Uromodulin in Sepsis Induced AKI.

for Acute Kidney Injury

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07295392

Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome

for Heart Failure

2 sites in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07273838·Phase 2

Apply to this trial

Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America

for Dialysis

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07262320

Apply to this trial

Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery

for Acute Kidney Injury

Sponsor: Uppsala University

Sex: All·Age: 0 - 16

Code: NCT07351149

Apply to this trial

Improving Patient Assessment After Acute Kidney Injury (AKI)

for Acute Kidney Injury

Sponsor: University of Nottingham

Sex: All·Age: 18 - 85

Code: NCT07569588

Apply to this trial

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

for Sepsis

14 sites incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 80

Code: NCT07215702·Phase 2

Apply to this trial

Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury

for Acute Kidney Injury

3 sites incl. Birmingham

Sponsor: Hope Biosciences LLC

Sex: All·Age: 18 - 75

Code: NCT06654193·Phase 1, Phase 2

Apply to this trial

The AminoECMO Pilot Trial

for Acute Kidney Injury

Sponsor: Australian and New Zealand Intensive Care Research Centre

Sex: All·Age: 18 - 65

Code: NCT07438262·Phase 2

Fluid Balance in Acute Kidney Injury in Critically Ill Patients

for Fluid Balance

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07338734

A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment With Vancomycin and Piperacillin-Tazobactam vs. Vancomycin and Cefepime in Hospitalized Patients

for Acute Kidney Injury

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06954129·Phase 4

Apply to this trial

Predictive Value of the Uric Acid/Albumin Ratio and Lactate in Sepsis Patients

for Sepsis-Related Mortality

Sponsor: Istinye University

Sex: All·Age: 65+

Code: NCT07332715

Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery

for Renal Perfusion

Sponsor: Istanbul University - Cerrahpasa

Sex: All·Age: 18 - 80

Code: NCT07635160

Apply to this trial

Risk of Acute Kidney Injury in Pulmonary Endarterectomy

for Acute Kidney Injury

Sponsor: China-Japan Friendship Hospital

Sex: All·Age: 18 - 85

Code: NCT07135206

The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score

for Rhabdomyolysis

Sponsor: University of Salford

Sex: All·Age: 60+

Code: NCT07158554

Apply to this trial

Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial

for Critical Illness

1 site in Framingham

Sponsor: MetroWest Artificial Intelligence Research Workgroup

Sex: All·Age: 18+

Code: NCT07293078·Phase 1, Phase 2

GENECARD - the Use of Genetic, Epigenetic, Metabolomic, Proteomic and Microbiotic Markers, Image and Voice Biomarker Analyses, and Pre- and Intraoperative Clinical Data - to Predict Early Complications After Cardiac Surgery.

for Postoperative Delirium (POD)

Sponsor: Medical University of Gdansk

Sex: All·Age: 18+

Code: NCT07345403

Modified Autologous Leukocyte Cells for the Treatment of Acute Kidney Injury After Cardiac Surgery

for Acute Kidney Injury

Sponsor: M2RLAB SL

Sex: All·Age: 18+

Code: NCT07052513·Phase 2

Apply to this trial

A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+

for Acute Respiratory Distress Syndrome

Sponsor: Vantive Health LLC

Sex: All·Age: 18+

Code: NCT07326215

Apply to this trial

Prevention of Cisplatin-induced Nephrotoxicity

for Acute Kidney Injury

Sponsor: Mahidol University

Sex: All·Age: Up to 18

Code: NCT06196853·Phase 2, Phase 3

Wise Choices in the Intensive Care Unit

for Critical Illness

Sponsor: Karolinska Institutet

Sex: All·Age: 18+

Code: NCT07013175

Apply to this trial

Timing of Renal Replacement Therapy in the Critically Ill Patients

for Acute Kidney Injury

Sponsor: Karolinska University Hospital

Sex: All·Age: 18+

Code: NCT03629977

Apply to this trial

French AKI Registry (FAKIR): A Multicenter Study on the In-Hospital Management and Outcomes of Severe Acute Kidney Injury in Nephrology Units

for Acute Kidney Injury

Sponsor: University Hospital, Strasbourg, France

Sex: All·Age: 18+

Code: NCT07123324

Use of Flozins (Empagliflozin/Dapagliflozin) for Prevention of AKI

for Coronary Artery Disease

Sponsor: Collegium Medicum w Bydgoszczy

Sex: All·Age: 18+

Code: NCT07231939

Apply to this trial

Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression

for Chronic Kidney Diseases

1 site in Pasedena

Sponsor: Ebima Clifford Okundaye

Sex: All·Age: 18 - 90

Code: NCT06866236·Phase 2, Phase 3

Acute kidney injury clinical trials — common questions

Are acute kidney injury clinical trials free to join?

Yes. Participating in a acute kidney injury clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a acute kidney injury clinical trial?

Each acute kidney injury study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a acute kidney injury trial near me?

Use the location controls above. We'll show recruiting acute kidney injury trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many acute kidney injury trials are recruiting right now?

We're currently tracking roughly 46 recruiting acute kidney injury trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Acute kidney injury trials by city

Birmingham, AL Cincinnati, OH San Francisco, CA Aurora, CO Boston, MA Palo Alto, CA Chicago, IL Clearwater, FL Irvine, CA Little Rock, AR Los Angeles, CA

Related specialties

Nephrology Kidney disease