Metabolic health Clinical Trials in Holly Springs, NC

As of July 2026, 2 paid clinical trials are recruiting for Metabolic health in Holly Springs, North Carolina. Metabolic health research tests incretin therapies, dual and triple agonists, and lifestyle interventions for obesity, type 2 diabetes, insulin resistance, metabolic syndrome, and NAFLD/NASH. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

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2 clinical trials for Metabolic health

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About research studies in Holly Springs

Holly Springs has approximately 2 recruiting research studies across a wide range of therapeutic areas. North Carolina hosts Duke University Medical Center, UNC Health, and Wake Forest Baptist Health, with strong programs in oncology, cardiovascular disease, and translational research anchored by Research Triangle Park.

Top Research Study Locations in Holly Springs

Researchers run research studies in Holly Springs, NC at 1 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
Sahana Optometry PLLC dba Family Eye WellnessDiabetes, Type 2, Obesity, Obesity and Overweight2

Active & Upcoming Studies in Holly Springs (2026)

Recruiting trials in Holly Springs grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Common conditions studied in Holly Springs

  • Diabetes, Type 2 (1 active study). Diabetes trials evaluate new insulin formulations, GLP-1 receptor agonists, continuous glucose monitoring technologies, and disease-modifying therapies.
  • Obesity (1 active study). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
  • Obesity and Overweight (1 active study). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
  • Overweight (1 active study). Recruiting Overweight studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Overweight and/or Obesity (1 active study). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
  • Type 2 Diabetes (1 active study). Type 2 diabetes studies test GLP-1 agonists, SGLT-2 inhibitors, and combination regimens aimed at glycemic control and cardiovascular risk reduction.

Leading research sponsors in Holly Springs

  • Pfizer

Local regulations and guidelines

Clinical trials in North Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. North Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Holly Springs. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Holly Springs

Hipa.ai aggregates every recruiting study in Holly Springs from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Holly Springs?

There are approximately 2 recruiting clinical trials in Holly Springs, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Holly Springs pay participants?

Most recruiting trials in Holly Springs compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Holly Springs?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Holly Springs?

The most common conditions under active study in Holly Springs include Diabetes, Type 2 (1), Obesity (1), Obesity and Overweight (1), Overweight (1), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Holly Springs?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Holly Springs on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Holly Springs?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Holly Springs?

Recruiting research sites in Holly Springs include Sahana Optometry PLLC dba Family Eye Wellness, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Holly Springs right now?

The largest active categories in Holly Springs are Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

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Related healthcare resources in North Carolina

Trials by condition in Holly Springs

Conditions in Metabolic health (Holly Springs, NC)