Paid Clinical Trials in Wake Forest, NC
As of August 2026, 18 paid clinical trials are recruiting in Wake Forest, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Wake Forest offers studies at sites including North Carolina Retina Associates for conditions such as Macular Degeneration, Diabetic Macular Edema, Geographic Atrophy, Geographic Atrophy (GA). Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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18 clinical trials
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)
Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration
Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
Top Research Study Locations in Wake Forest
Researchers run research studies in Wake Forest, NC at 11 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| North Carolina Retina Associates | Diabetic Macular Edema, Age-related Macular Degeneration (AMD), DME | 6 |
| NC Retina Associates | Macular Degeneration, Age-Related Macular Degeneration, Choroidal Neovascularization | 2 |
| North Carolina Retina Associates (Wake Forest) | Macular Edema Secondary to Inflammation | 2 |
| Wake Forest, NC | Branch Retinal Vein Occlusion (BRVO), Neovascular (Wet) Age-Related Macular Degeneration, Neovascular Age-Related Macular Degeneration (NVAMD) | 2 |
| Adverum Clinical | Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD | 1 |
| Duke Health | Patellar Dislocation, Patellar Dislocation, Recurrent, Patellar Instability | 1 |
| NC Retina Associates-RCA | Neovascular Age-related Macular Degeneration, nAMD | 1 |
| North Carolina Retina Associates, S.C. | Age - Related Macular Degeneration (AMD), Geographic Atrophy (GA) | 1 |
| Wake Forest University Baptist Health - Dept of Gastroenterology | Erythropoietic Protoporphyria (EPP), X-Linked Porphyria (XLP) | 1 |
| Wake Forest University Health Sciences | Hemorrhagic Shock, Trauma Injury | 1 |
| Wake Forest, North Carolina | Branch Retinal Vein Occlusion (BRVO), Neovascular Age-Related Macular Degeneration (NVAMD) | 1 |
Active & Upcoming Studies in Wake Forest (2026)
Recruiting trials in Wake Forest grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Eye & vision (15 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration · Phase 1, Phase 2 · Eyconis INC.
Common conditions studied in Wake Forest
- Macular Degeneration (3 active studies)
- Diabetic Macular Edema (2 active studies)
- Geographic Atrophy (2 active studies)
- Geographic Atrophy (GA) (2 active studies)
- Macular Edema Secondary to Inflammation (2 active studies)
- Neovascular Age-Related Macular Degeneration (nAMD) (2 active studies)
Leading research sponsors in Wake Forest
- Boehringer Ingelheim
- EyeBiotech Ltd.
- Kodiak Sciences Inc
- 4D Molecular Therapeutics
- Adverum Biotechnologies, Inc.
Frequently asked questions
How many paid clinical trials are currently recruiting in Wake Forest?
There are approximately 18 recruiting clinical trials in Wake Forest, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Wake Forest pay participants?
Most recruiting trials in Wake Forest compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Wake Forest?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Wake Forest?
The most common conditions under active study in Wake Forest include Macular Degeneration (3), Diabetic Macular Edema (2), Geographic Atrophy (2), Geographic Atrophy (GA) (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Wake Forest?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Wake Forest on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Wake Forest?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Wake Forest?
Recruiting research sites in Wake Forest include North Carolina Retina Associates, NC Retina Associates, North Carolina Retina Associates (Wake Forest), among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Wake Forest right now?
The largest active categories in Wake Forest are Eye & vision (15). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.