As of August 2026, 700 paid clinical trials are recruiting in Chapel Hill, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Chapel Hill offers studies at sites including University of North Carolina at Chapel Hill for conditions such as Breast Cancer, Multiple Myeloma, Obesity, Ulcerative Colitis. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Chapel Hill, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of North Carolina at Chapel Hill | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 145 |
| University of North Carolina | Breast Cancer, Metastatic Breast Cancer, Ulcerative Colitis | 98 |
| UNC Lineberger Comprehensive Cancer Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia | 88 |
| The University of North Carolina at Chapel Hill | Hypertension, ACL Tear, AML | 18 |
| UNC Chapel Hill | Lupus Nephritis, Lymphatic Malformations, Barrett's Esophagus | 17 |
| Lineberger Comprehensive Cancer Center | Endometrial Cancer, Adolescent and Young Adult With Brain Cancer, Advanced Solid Tumors | 13 |
| University of North Carolina Chapel Hill | Alport Syndrome, Articular Fractures, Asthma (Diagnosis) | 13 |
| University of North Carolina Medical Center | Breast Neoplasms, Neoplasm Metastasis, Atrial Fibrillation | 10 |
| University of North Carolina - Chapel Hill | Obstetrical Complications, Ann Arbor Stage I Diffuse Large B-Cell Lymphoma, Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | 9 |
| University of North Carolina, Chapel Hill | Hearing Loss, Sensorineural, Acute Myeloid Leukemia (AML), Aging | 9 |
| UNC Hospitals, The University of North Carolina at Chapel Hill | Cachexia, Melanoma, Cutaneous Malignant, Metastatic Melanoma | 9 |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Breast Cancer, Chronic Myeloproliferative Disorders, Leukemia | 8 |
| UNC Hospitals | Comparative Effectiveness, Family Engagement, Health Care | 8 |
| University of North Carolina at Chapel Hill, Department of Radiation Oncology | Head and Neck Cancer, Sarcoma, Cancer | 6 |
| Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill | Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II | 5 |
| University of North Carolina At Chapel Hill | Chronic Lymphocytic Leukemia, Myeloproliferative Neoplasms, Small Lymphocytic Lymphoma | 5 |
| The University of North Carolina | Breast Cancer, Breast Neoplasms, Kidney Neoplasms | 4 |
| UNC Hospitals, University of North Carolina at Chapel Hill | Acute Myeloid Leukemia, Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With KMT2A Rearrangement | 4 |
| Univeristy of North Carolina at Chapel Hill | Cystic Fibrosis, Drug Induced Liver Injury, Endometrial Cancer | 4 |
| University of North Carolina Hospitals | Carotid Artery Calcification, Carotid Artery Diseases, Gastroschisis | 4 |
| University of North Carolina School of Medicine | Barrett Esophagus, Barretts Esophagus With Dysplasia, Brain Injury | 4 |
| Clinical Trial Site | AQP4+ NMOSD, Generalized Myasthenia Gravis, Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy | 3 |
| North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology | Allergy, Alpha-Gal Syndrome, Peanut Allergy | 3 |
| UNC | Acute Kidney Injury, Chronic Kidney Disease(CKD), Epidemiology | 3 |
| UNC Center for Health Promotion and Disease Prevention | Child Obesity, Down Syndrome, Obesity | 3 |
Recruiting trials in Chapel Hill grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 700 recruiting clinical trials in Chapel Hill, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Chapel Hill compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Chapel Hill include Breast Cancer (27), Multiple Myeloma (17), Cancer (15), Obesity (14), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chapel Hill on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Chapel Hill include University of North Carolina at Chapel Hill, University of North Carolina, UNC Lineberger Comprehensive Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Chapel Hill are Cancer & tumors (245), Diabetes & metabolic (44), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.