Paid Clinical Trials in Shelby, NC
As of September 2026, 29 paid clinical trials are recruiting in Shelby, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Shelby offers studies at sites including Atrium Health Cleveland/LCI-Cleveland for conditions such as Breast Cancer, Dry Eye Disease (DED), Gout, Acute Migraine. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Shelby
Trials by drug in Shelby
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Newly added in Shelby
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
29 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
A Study of Dotinurad Versus Allopurinol in Participants With Gout
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants
A Clinical Study Evaluating Licaminlimab for Dry Eye Disease
An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
E-Mindfulness Approaches for Living After Breast Cancer
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED
Top Research Study Locations in Shelby
Researchers run research studies in Shelby, NC at 16 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Atrium Health Cleveland/LCI-Cleveland | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 8 |
| Shelby Clinical Research | Gout, Type 2 Diabetes, Uncontrolled Gout | 3 |
| Carolina Research Center Inc | Obesity, Overweight, Uncontrolled Gout | 2 |
| Carolina Research Center, Inc | Acute Migraine, Migraine | 2 |
| Shelby Clinical Research, LLC - North Carolina | Gout, Tophaceous Gout | 2 |
| CORE, Inc | Dry Eye Disease (DED) | 1 |
| Cardinal Clinical Research, LLC - Shelby | Focal Segmental Glomerulosclerosis | 1 |
| Carolina Research Center | Osteoarthritis | 1 |
| Carolina Research Center, Inc. | Chronic Obstructive Pulmonary Disease (COPD) | 1 |
| Core, Inc. | Dry Eye Disease (DED) | 1 |
| GSK Investigational Site | Pulmonary Disease, Chronic Obstructive | 1 |
| Glaukos Investigative Site | Persistent Corneal Epithelial Defect | 1 |
| Levine Cancer Institute | Metastatic Breast Cancer | 1 |
| Local Institution - 1252 | Psychosis Associated With Alzheimer's Disease | 1 |
| Nephrology Associates of the Carolinas | End Stage Kidney Disease | 1 |
| Vanda Investigational Site | Dry Eye | 1 |
Active & Upcoming Studies in Shelby (2026)
Recruiting trials in Shelby grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (9 active studies)
Eye & vision (3 active studies)
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
- A Clinical Study Evaluating Licaminlimab for Dry Eye Disease · Phase 2, Phase 3 · Oculis
Diabetes & metabolic (2 active studies)
- Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION) · Phase 3 · Amgen
- A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide · Phase 2 · Eli Lilly and Company
Neurology & pain (2 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Common conditions studied in Shelby
- Breast Cancer (2 active studies)
- Dry Eye Disease (DED) (2 active studies)
- Gout (2 active studies)
- Acute Migraine (1 active study)
- Anatomic Stage II Breast Cancer AJCC v8 (1 active study)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (1 active study)
Leading research sponsors in Shelby
- NRG Oncology
- Crystalys Therapeutics
- Amgen
- Eli Lilly and Company
- Kallyope Inc.
Frequently asked questions
How many paid clinical trials are currently recruiting in Shelby?
There are approximately 29 recruiting clinical trials in Shelby, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Shelby pay participants?
Most recruiting trials in Shelby compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Shelby?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Shelby?
The most common conditions under active study in Shelby include Breast Cancer (2), Dry Eye Disease (DED) (2), Gout (2), Acute Migraine (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Shelby?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Shelby on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Shelby?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Shelby?
Recruiting research sites in Shelby include Atrium Health Cleveland/LCI-Cleveland, Shelby Clinical Research, Carolina Research Center Inc, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Shelby right now?
The largest active categories in Shelby are Cancer & tumors (9), Eye & vision (3), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.