As of July 2026, 203 paid clinical trials are recruiting in Raleigh, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Raleigh offers studies at sites including Duke Cancer Center Raleigh for conditions such as Heart Failure, Breast Cancer, Coronary Artery Disease, Obesity. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Raleigh has approximately 203 recruiting research studies across a wide range of therapeutic areas. North Carolina hosts Duke University Medical Center, UNC Health, and Wake Forest Baptist Health, with strong programs in oncology, cardiovascular disease, and translational research anchored by Research Triangle Park.
Researchers run research studies in Raleigh, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Duke Cancer Center Raleigh | Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 | 18 |
| Duke Women's Cancer Care Raleigh | Recurrent Endometrial Carcinoma, Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8 | 17 |
| WakeMed | End Stage Renal Disease, Heart Failure, Hemodialysis Access Failure | 11 |
| NC Heart and Vascular Research, LLC | Coronary Artery Disease, Cardiovascular Diseases, Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities | 7 |
| UNC Health Cancer Care Raleigh | Anatomic Stage II Breast Cancer AJCC v8, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 7 |
| UNC Health Cancer Care Wakefield | Anatomic Stage II Breast Cancer AJCC v8, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 7 |
| NC Heart and Vascular Research | Heart Failure, Acute Myocardial Infarction (AMI), Cardiovascular Risk | 6 |
| Accellacare of Raleigh | Atherosclerotic Cardiovascular Disease, Chronic Idiopathic Constipation (CIC), Diabetes Mellitus, Type 1 | 5 |
| WakeMed Health & Hospitals | Intubation Complication, Child Social-Emotional Development, Epigenetic Aging | 5 |
| Associated Urologists of North Carolina | Benign Prostatic Hyperplasia, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-Muscle Invasive Bladder Neoplasms | 4 |
| Duke Raleigh Hospital | Atherosclerosis of Extremities, Breast Cancer, Breast Reconstruction | 4 |
| North Carolina State University | Alzheimer Disease, Blood Pressure, Diabetes Mellitus Risk | 4 |
| Eximia Research - NC, LLC | Acute Migraine, Diabetes, Type 2, Migraine | 3 |
| Raleigh Neurology Associates | Chronic Inflammatory Demyelinating Polyneuropathy, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| ClinTrial Research, LLC | Crohn's Disease, Ulcerative Colitis | 2 |
| Eximia Research - Raleigh | Diabetic Peripheral Neuropathic Pain | 2 |
| M3 Wake Research, Inc | Metabolic Dysfunction-Associated Steatohepatitis, Obesity Associated With Defects in Leptin-melanocortin Pathway | 2 |
| M3 Wake Research, Inc. | Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| NC Heart and Vascular | Coronary Artery Disease, Hypertension | 2 |
| NC State University | Diet Interventions, Food Security, Fruit and Vegetable Intake | 2 |
| North Carolina Nephrology, PA | Atherosclerotic Cardiovascular Disease in Patients With ESKD, Primary IgA Nephropathy | 2 |
| Rex Healthcare | Chronic Myeloproliferative Disorders, Cognitive/Functional Effects, Leukemia | 2 |
| TG Therapeutics Investigational Trial Site | Relapsing Multiple Sclerosis, Multiple Sclerosis | 2 |
| UNC Health Rex | Delirium, Major Depressive Disorder | 2 |
Recruiting trials in Raleigh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in North Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. North Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Raleigh from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 203 recruiting clinical trials in Raleigh, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Raleigh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Raleigh include Heart Failure (9), Breast Cancer (5), Coronary Artery Disease (5), Obesity (4), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Raleigh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Raleigh include Duke Cancer Center Raleigh, Duke Women's Cancer Care Raleigh, WakeMed, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Raleigh are Cancer & tumors (48), Cardiovascular (22), Neurology & pain (20). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.