As of September 2026, 188 paid clinical trials are recruiting in Raleigh, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Raleigh offers studies at sites including Duke Cancer Center Raleigh for conditions such as Heart Failure, Coronary Artery Disease, Type 2 Diabetes Mellitus, Anatomic Stage II Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Raleigh, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Duke Cancer Center Raleigh | Advanced Hepatocellular Carcinoma, Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate | 17 |
| Duke Women's Cancer Care Raleigh | Anatomic Stage II Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Anatomic Stage IIIA Breast Cancer AJCC v8 | 16 |
| WakeMed | End Stage Renal Disease, Heart Failure, Hemodialysis Access Failure | 11 |
| NC Heart and Vascular Research, LLC | Coronary Artery Disease, Cardiovascular Diseases, Atherosclerosis | 7 |
| Duke Raleigh Hospital | Advanced/Metastatic Urothelial Cancer, Atherosclerosis of Extremities, Breast Cancer | 5 |
| WakeMed Health & Hospitals | Intubation Complication, Child Social-Emotional Development, Epigenetic Aging | 5 |
| Accellacare of Raleigh | Atherosclerotic Cardiovascular Disease, Chronic Idiopathic Constipation (CIC), Obesity | 4 |
| NC Heart and Vascular Research | Heart Failure, Iliofemoral; Thrombosis, Pulmonary Embolism | 4 |
| North Carolina State University | Alzheimer Disease, Blood Pressure, Diabetes Mellitus Risk | 4 |
| UNC Health Cancer Care Raleigh | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 4 |
| UNC Health Cancer Care Wakefield | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 4 |
| Associated Urologists of North Carolina | Benign Prostatic Hyperplasia, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-muscle Invasive Bladder Cancer | 3 |
| NC Heart and Vascular | Carotid Artery Calcification, Carotid Artery Diseases, Coronary Artery Disease | 3 |
| Accellacare - Raleigh | Atherosclerotic Cardiovascular Disease (ASCVD), Clostridoides Difficile Associated Disease, Elevated Lp(a) | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Care Access | Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes | 2 |
| Duke Women's Cancer Care Raleigh (Pharmacy location and location of CT, MRI and Bone scan machines) | Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate, Hormone Sensitive Prostate Cancer | 2 |
| Eximia Research - NC, LLC | Acute Migraine, Migraine | 2 |
| M3 Wake Research, Inc. | Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| NC State University | Diet Interventions, Food Security, Fruit and Vegetable Intake | 2 |
| Rex Healthcare | Chronic Myeloproliferative Disorders, Cognitive/Functional Effects, Leukemia | 2 |
| TG Therapeutics Investigational Trial Site | Relapsing Multiple Sclerosis, Multiple Sclerosis | 2 |
| Velocity Clinical Research | Epilepsy, Focal Epilepsy, Focal Seizure | 2 |
| WakeMed Raleigh Campus | Carcinoma, Non-Small-Cell Lung, Lumbar Spinal Stenosis | 2 |
| ClinTrial Research, LLC | Ulcerative Colitis, Crohn's Disease | 2 |
Recruiting trials in Raleigh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 188 recruiting clinical trials in Raleigh, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Raleigh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Raleigh include Heart Failure (8), Coronary Artery Disease (6), Type 2 Diabetes Mellitus (5), Anatomic Stage II Breast Cancer AJCC v8 (4), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Raleigh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Raleigh include Duke Cancer Center Raleigh, Duke Women's Cancer Care Raleigh, WakeMed, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Raleigh are Cancer & tumors (43), Cardiovascular (21), Neurology & pain (18). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.